r/genetics

My daughter’s eyes are completely brown, both parents don’t have brown eyes.
▲ 389 r/genetics

My daughter’s eyes are completely brown, both parents don’t have brown eyes.

My husband has blue eyes (left) my 1 year old has completely brown eyes (middle) and I have green and hazel eyes but they are very light for a hazel.

Both of us have no brown eyes in the family, my husband has really struggled with this, he is from an Irish family who are all fair in appearance. They keep commenting on her eyes and I don’t really have the explanation for it. I’ve never seen someone with completely flat brown eyes either which is what she has.

PS- my daughter is the most beautiful and special little angel and I personally love her beautiful eyes. She is perfect to me and she really is gorgeous and healthy ❤️

u/Careful-Size3756 — 15 hours ago

Early puberty.

Can early puberty affect height? Can it prevent a child from reaching their height potential?

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u/VGAddict — 8 hours ago

Genetic engineering

Im really interested in this field but what I have realized with every career path I looked into their is always a plot twist. So please share with me what makes this career path bad 😭. I really don’t want to hear anything bad anymore. I’ve posted so many careers and a lot of people tell me everything that’s bad. But I’m still glad they told me because I don’t want to waste time following a career that isn’t worth it. So please share the good and bad of Genetic engineering. The field sound so interesting though.

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u/QuietFine8724 — 7 hours ago

Baylor Genetics information breach notice...I've never had genetic testing.

I had a letter come in saying that my information was accessed in a data breach at Baylor Genetics, but I've never had genetic testing. I don't think it's a scam either as I see a notice on their website and some news stuff.

How can I know why they have my information and what information they even have? Or rather like can I legally know how and why I'm attached to them?

(My credit and stuff was already frozen and all that because I simply froze it a long while ago out of caution)

I put this in r/Legal but figured here may be better? If I'm breaking rules feel free to delete this, sorry.

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u/North_Awareness_6006 — 10 hours ago

How did I end up this short?

My mom is 5'5 and my dad is 5'8, my maternal grandfather was 5'11, and so were his brother and dad, and my paternal uncle and grandfather are 5'8. According to the mid-parental target height, I should be 5'9, but I ended up 5'2, and my sister is 5'1.

How did I end up shorter than almost everyone in my family?

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u/VGAddict — 1 day ago

Invitae results missing?

Hi, I recently got my Invitae results. The panel for genes analyzed said that they were testing a total of 265 genes but my results only show 245 genes tested. Does anyone have an explanation for why this would be or a simular experience?

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u/Dazzling-Spite-2980 — 1 day ago

Wich epigenetics topic should i choose for a one year research?

Just got in this program and now i need tô choose a epigenetics area for research. I Just studied the basics, theres so much about it that it looks almost impossible to choose just one.

Can my fellows Reddit members tell me some nice topics so i can choose more easily?

A Nice week for everyone

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u/Nice_Muscle_5 — 1 day ago
▲ 376 r/genetics

XXY female.. my full Y matches sons

Discovered I’m an XXY female whose Y chromosome matches my sons Y 99.9%. I assumed microchimerism but from what I understand, it is impossible for 30X sequencing to detect a full Y chromosome (from son) and that you need 500X+ read depth to detect it. I’m physically female (inside and out) and perfectly fertile and have found autosomal variants that resulted in me being a healthy female. There are a lot of other interesting/novel findings as well. I’d appreciate any expertise and would be happy to answer any questions you may have and can provide more details.

(Update: I won’t be commenting further.. my plan is to do further testing).

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u/Some-Comedian-264 — 3 days ago

On rare occasions, children can be born with vestigial tails or pseudotails, resulting from the activation of dormant but still present DNA coding for faulty characteristics.

u/llartoonblazor — 2 days ago

Free Genetic Screening Healthpartners Administered by Helix - Good or bad idea? Normally I'm against having my data out there but does this seem like it's worth the benefits?

Now when I say I don't want my data out there for my genetics, I realize my genes are not that different from the already available pool of genetic information. I just feel like no one should have easy access to my exact make up.

But this study seems like there could be some pros. Any major cons?

Sorry, you must have a lot of these posts on this sub

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u/TehDonkey117 — 2 days ago

Do any of you have a rare biological gene modification or medical condition?

Or does anybody close to you?

If so, which ones and what is your personal experience with it (or them.)

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u/0ki_x — 3 days ago

Mid-Parental Target Height.

How accurate is the Mid-Parental Target Height for predicting a child's height? My mom is 5'5 and my dad is 5'8, so my target height should be 5'9, with a range of 5'5-6'0. I ended up 5'2.

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u/VGAddict — 4 days ago

Career (and life) Advice

Hi everyone! I come to you guys for your advice and help! Also apologies in advance if this is too long. So a little bit about me : I’m 26, with a background (bachelors) in biomedical science, majoring in medical genomics. I finished my studies just over 2 years ago (later than anticipated – thanks to covid). I have never wanted to do medicine, but research in genetics has always fascinated me. Now perhaps I made a mistake with my undergrad (maybe there was something else I should’ve done in genetics, I’m not sure). A lot (mostly) of my lab component during my undergrad was affected because of covid and classes (along with practicals) being moved online, so I unfortunately missed out on a large part of the hands on component. I did a placement (not related to genetics) in ecology – not out of choice, but the stuff up on my student advisor part (I was wrongly informed about my course map- and had to take up my placement unit at the very last minute because of it, and did not have enough time to find a more aligned/appropriate placement. The rules around the completion and other aspects of my studies were a bit more complex due to me being an international student on a visa. Now post graduation, I have spent so long trying to find a role that’s relevant to my background and where I want to be eventually. And I have truly tried (and still am). From my experience and the advice I have received over the past 2  years have been to get more qualifications (even the most entry level roles in my background prefer graduate with at least an honours degree – and understandably so!), and to make connections!!
Anywho, girl still needs to pay her bills while searching for the right path/role, so I’ve worked in roles that unfortunately wont really help/add to the skills/experience I need to get back into my field. But that’s okay, that’s life (I guess? At least what I tell myself when I get overwhelmed and scared that I’ve messed up? Even though I know I’ve been trying my hardest the whole time).
Now to the point (finally!! I know), I feel very lost (20s are so scary) about everything, but especially my career. Below are some of the pointers regarding where I currently land:
• I used to be so sure that I want to pursue research but I’m not so sure anymore. I thought a job within a research facility would help clear my doubts but I’ve not been able to find work (for even the most entry level junior roles) in a place like that.
• I have been looking into genetic engineering recently (and I understand its not a job like say a civil or software engineer, but a field of genetics manipulation via different tools) and I’ve found this so interesting.
• I am a temporary visa holder in Australia, so if I went to uni here (for my masters etc) it would be unbelievably expensive, even with most scholarships (girl is still paying off her student loans for her undergrad). Moreover, if I did a masters, I would likely not finish it in time of my current visa expiry. And at the moment I unfortunately do not qualify to apply/consider a PR. (Main reason also for not just doing honours – because as much as I like school, its very very expensive. So I have to be much more strategic).
• I am very open to moving somewhere else (can’t do my home country, as there is hardly any scope of human genetics going on there – hence the move for my undergrad).
• I love science, and god I love genetics, and I want to go back to school. I just am very confused as to what courses I should be looking for and where abouts (I know where NOT to look – and that would be USA, Canada, UK, NZ) (no hate to any of these places, but migration to these places is not an option for me personally.)
• I have lived in Australia for about 4.5 years now, and I love it! If I have to leave it for my studies, I hope I have the opportunity in the future to come back hopefully!
 
If anyone has felt similar in the lives, or have been in a similar situation, how did you navigate through it? And if anyone has any advice on what courses/universities/countries I should look into, I would love nothing more than some advice please!
Thank you for reading through my Monday morning life crisis, and for your time!
Bigggg love!!

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u/GargiBakshi — 3 days ago

Made a grid of every blood type pairing and what a child can and cannot be

I went down a rabbit hole on ABO inheritance this week and ended up making this, mostly because I kept having to redraw the same Punnett square over and over to answer one question.

Laying all sixteen pairings out at once made a few things click that never did when I worked them one at a time. AB and O parents can never have an AB or an O child, which feels backwards until you write out the gametes. And A with B is the only pairing in the whole grid that can produce all four types, which I did not expect.

My favourite one is A with A though. Two type A parents really can have a type O child, because type A is either AA or AO and a blood test genuinely cannot tell you which. I imagine that has caused some awkward conversations over the years!

I wrote the impossible types into every cell too, since that is usually the part a question is actually testing.

Would love to hear if I have oversimplified anything, especially on the Rh side. It is free and there is no signup if anyone wants it: biochemtools.com/blood-type-punnett-square-calculator.html

u/KaleidoscopeOk4028 — 5 days ago

Im thinking getting a genetics phd

For reference I am a high school currently

I know this is a dumb queshtion but I cant really figure out what degree id need if I wanted to get a PhD in genetics (or virology thats my other option)

Sense ive read a few places you can get a PhD in like microbiology or a similar feild then branch into genetics BUT idk if thats true and the information around this stuff is kinda vague

Also last note, would it be a problem id I emailed a professor with a degree in this stuff the same queshtion

Thank you for your time.

EDIT im from the USA and Washington state if that helps :D

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u/Amber-The-Third — 6 days ago

What does genetics say about inheritance of behavioural characters

Are behavioural characteristics such as selfishness, kindness inherited through genes or contributed more from enviorment, society, culture? If it's genetic which side(mother/father) contributes more?

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u/heritage1022 — 6 days ago

New Cat. What Color?

I got this cat. She was labelled as a dilute calico at the shelter. Her patchiness makes me question that, since usually calicos I see have separate large sorta spots, instead of marbled or patchy like her. My next thought was maybe tortoiseshell, but she has white on her legs and tummy.
What do you think?

PS: Sorry if this isnt the right place for this, I wasn't able to post in the cats reddit and I saw previous cat posts in here. Also ignore her red ears and skinniness, I just adopted her today and shes been kept outside in a coop, I think her ears are sunburned.

u/Zealousideal-List241 — 5 days ago

how do you resolve this exercice ?

  1. The pedigree below shows the family tree of a family affected by a recessive monogenic disorder that is not sex-linked. If the frequency of heterozygotes in the population in question is negligible, what is the probability that the child in the last generation will have the disorder?

1: 1/16

2: 1/8

3: 1/4

4: 1/2

thanks a lot

u/Sure-Roof-7681 — 5 days ago

Why is ‘lab leak theory’ still considered as possible?

So right off the bat I understand that this is just how science is written, confidence is always hedged out of need for caution and precision. It just appears to me that we have sufficient research to rule it out to a degree in which entertaining it at all feels a bit absurd.

For context, I thought up until very recently that there was enough room for some reasonable doubt in zoonotic origin even though it was more likely the explanation than a lab leak. Then, while debating someone who favored lab leak, I started catching up on some studies from just the past 2-3 years and realized how far behind I was.

This study in particular really put it all together for me in a way where I could no longer conceive of a way in which the alleged cover ups or a lab made source could ever explain all these studies when placed together:

https://www.cell.com/cell/fulltext/S0092-8674(24)00901-2?utm_campaign=Press%20Package&utm_medium=email&_hsmi=324423428&utm_content=324423428&utm_source=hs_email#

>

>Multiple lines of evidence are consistent with the infection of wildlife animals with SARS-CoV-2 in the Huanan market. Animal carts, a cage, a garbage cart, and a hair/feather removal machine from a wildlife stall tested positive for SARS-CoV-2, and there was more DNA from mammalian wildlife species in these samples than human DNA. The surrounding stalls also had relatively higher rates of SARS-CoV-2 positivity, and drains adjacent to and downstream of this wildlife stall tested positive for SARS-CoV-2. Finally, there were several other viruses known to infect wildlife in these samples. These data indicate either that the animals present at this stall shed the SARS-CoV-2 detected on the animal equipment or that early unreported human case(s) of COVID-19 shed virus in the exact same location as the detected animals. Under a zoonotic scenario, viral shedding by infected animal handlers is expected to occur after shedding by the animals they were infected by. Therefore, human viral shedding post-zoonosis could plausibly also explain these data; in such a case, the animals brought into the stall are therefore still the most likely candidates for the zoonotic source. Although either animal or human viral shedding is consistent with these data, only a zoonotic origin of SARS-CoV-2 directly predicts co-detection of SARS-CoV-2 and wildlife genetic material.

>It has been proposed that humans could have introduced the virus into the Huanan market.^(25)^(,)^(57) It is most likely that there were human infections of SARS-CoV-2 earlier than the first documented and hospitalized market cases, including unascertained market cases or contacts thereof. However, the detection of lineage B and lineage A both within and indirectly (geographically) linked to the Huanan market implies that SARS-CoV-2 most likely emerged there or its supply chain before the tMRCA, by which time there would have been an estimated median of just three people infected (95% HPD, 1–18).^(11) Any hypothesis of COVID-19’s emergence has to explain how the virus arrived at one of only four documented live wildlife markets in a city of Wuhan’s size at a time when so few humans were infected.^(3) Human introductions linked to the animal trade offer one explanation for this, and the introduction of the virus by an animal trader or farmer cannot be excluded, but these hypotheses are challenged by phylodynamic evidence for multiple spillovers.^(11) The introduction by an animal trader infected by animals upstream of the market is further challenged by the probability that transmission chains dependent upon a single human would likely go extinct,^(17) while a sustained interface between infected animals and humans in a market is more likely to result in the establishment of an epidemic.

I am not a geneticist, I took a few course as part of my major but that was years ago. Am I missing something though? Is there a flaw in the methodology of any of these studies I’m not seeing? Have I just fundamentally misunderstood what I have read? Or are communicators being far too charitable in messaging about how confident we can be about the origin?

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u/Daniel_Spidey — 7 days ago

Could one man and one woman repopulate the earth?

This came up in r/askanything and I really don’t know the answer. What would be the results?

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u/0bfuscatory — 7 days ago