r/ladiesover40onGLP1s

I haven’t posted much on Reddit, I usually just scroll and read every one else’s posts, but I wanted to share a little accomplishment that I didn’t see coming..

I am a 57 year old female, about 5’-4”, starting weight 6 months ago was 255 lbs and I’m about 193 lbs this morning - so about 60 pounds down.

My small victory was - crossing my legs for the first time in maybe ten years or so!!

I was so shocked when during a presentation at work that we did via Teams (wearing a suit that I dug out from my closet the night before from years ago) realized that my legs had muscle memory or something because all of the sudden they were crossed! And when I looked down at my lap and legs - I think I looked pretty good!!

***split dose update. Continuing on split dose- seems to be working for me. I am much more balanced throughout the week and scale is moving again. Best part- no symptoms. Cannot tell you what a relief that has been. If any of you suffer from nausea, vomiting, fatigue etc. look into it.

For context, I usually donate to a local church or goodwill. However, I have a lot of nice clothes that I’ve only worn a few times or for a season. They are nice brands and in good condition from places like Anthropologie and Nordstrom. I’ve posted on Vinted and Poshmark, but I really thought many of these communities could benefit from buying gently used items during weight loss journeys.

I’m parting with a lot of size 32 pants. Anyone have any ideas…or interest?

Does anyone have access to the whole article?

Regina Castaneda, Dima Bechenati, Elif Tama, Rene Rivera Gutierrez, Maria A Espinosa, Jose Villamarin, Tamim I Rajjo, Andres Acosta, Stephanie Faubion, Chrisandra Shufelt, Maria D Hurtado Andrade. The role of menopause hormone therapy in modulating tirzepatide-associated weight loss in postmenopausal women with overweight or obesity: a retrospective cohort study. The Lancet Obstetrics, Gynaecology,, 2026; 2 (2): e118 DOI: 10.1016/S3050-5038(25)00145-1

What has your lived experience been?

Im 64, on 2.5 mg Zep, just took my 9th shot. I started MHT patch 3 weeks ago and I have a waist again! I didn’t realize how much I missed having one! I had to do some arm-twisting to get the MHT from my OB (She told me that although the medication was likely to help me, she didn’t recommend it because it was ((gasp)) ‘off-label’)

There is a very tiny increased Cardiovascular risk because I didn’t start the MRT right away.
I feel angry because I have asking for this medication and suffering the brain fog and bone loss and stubborn weight for 8 years but I was refused or allowed myself to be talked out of it.
I feel sad because I suffered needlessly for so long and lost so much bone density needlessly.
I feel grateful that I can start now.
I feel hopeful that because I started now I will be able to continue for a long time,as the thinking continues to evolve.
I want every eligible person to know about the rapidly changing landscape so that no one else has to suffer needlessly.