u/Appeltaart22

My 5th IVF cycle had a rocky start. I started 2 days of decapeptyl (gnra agonist), but because my progesterone was elevated on day 3 (6.2 nmol/L), my cycle was cancelled. However, when we checked 4 days later, my progesterone was low again, so we resumed stimulation with decapeptyl and gonal F.

After the first dose of decapeptyl, my LH rose to 26.1 u/L. I used it for 2 days last week. Yesterday I started decapeptyl again after few days of no medication, so I'm worried I had the LH peak again and exposed my eggs to too much LH. I read that this can impact maturity and euploidy. Can someone reassure me that this is okay, or should I ask for an antagonist instead of continuing with an agonist protocol?

I hate all the unexpected turns and disappointments that go with IVF..

My IVF cycle was just cancelled because of elevated progesterone after starting decapeptyl. I am utterly confused and I hope someone can reassure me that this cycle was not cancelled for nothing.

Timeline:
April 13th start of my period
April 29th positive ovulation test
May 12th start of light period, contacted my clinic to start a new IVF cycle
May 13th: US showed AFC of 5, which is high for me (I normally have an AFC of 2-3), so I got my hopes up. Lab showed low estrogen (126 pmol/L) and slightly elevated progesterone (2.4 nmol/).
May 14th: start with decapeptyl
May 15th: another US showed a greyish follicle, possibly a small corpus luteum. Lab showed my progesterone had risen to 6.2 nmol/L.

The cycle was cancelled because they suspected I had just ovulated. But how is that even possible during a period and 2 weeks after an LH peak?! And with low estrogen? Could it be that the decapeptyl (GnRH agonist) stimulated the old corpus luteum to start secreting progesterone again?

Even if I just ovulated, we could to do a lutheal phase start right? Or do you agree with my clinic that this cycle should be cancelled? I waited so long for this one and really hoped I could get more that 2 eggs this time because of the higher AFC :(.