
Mechanoreceptors like Meissner’s Corpuscles are incapable of undergoing mitosis
I’m not knocking foreskin restoration, and it can clearly help profoundly. I’m doing it myself, and I won’t be stopping until full coverage. But it’s important to distinguish between skin cells and mechanoreceptors. Mechanoreceptors are specialized sensory nerve endings that detect touch, pressure, stretch, and vibration. In sexually sensitive tissue, they are a major part of how physical stimulation gets converted into pleasurable sensation and sent through sensory nerves to the brain.
Ordinary skin cells can multiply through mitosis during tissue expansion, but mature mechanoreceptors are not known to undergo mitosis. As a result, restoration expands the tissue around the existing mechanoreceptors rather than generating new ones.
The tissue you generate through mitosis is really just “extra skin” to me rather than the highly specialized, mechanoreceptor rich native foreskin. The majority of sexual mechanoreceptors are in the inner foreskin/fenuluar area, and they are just lost forever to amputation unfortunately.