u/Comfortable_End7154

I’ve been on spironolactone since March 2025, first 3 months at 50mg then I was moved up to 100mg. Spironolactone has been the only thing to clear my skin, I’ve never felt happier. But there’s a catch. In August last year i started with vulva/labia burning and initially thought it was maybe contact dermatitis from a wash or detergent. I ruled everything out and couldn’t find a cause, it then got worse and i developed uti symptoms, my vulva is red,sore, burns and sometimes swells, I was told by my gynaecologist I have vulvovaginitis but nothing works… antibiotics topical/oral, antifungals topical/oral, topical steroids. It’s now affecting my urethra which I’ve been told after an examination is red and irritated causing discomfort similar to a uti. I believe spironolactone has affected my hormones and caused my vaginal problems. I dread coming off the medication as it was my last resort but i definitely can’t handle the vaginal side effects anymore. Has anyone else had these problems and once stopping spironolactone they went away?
* I have also reduced my dose to 75mg with no improvement to side effects.

reddit.com
u/Comfortable_End7154 — 17 days ago