u/Deep_Boysenberry_672

I started midodrine yesterday. Not sure if it's helping, honestly.

I was prescribed 2.5mg twice daily, but yesterday I took a half-dose to start with. I didn't notice any side effects, but I couldn't tell if it was helping, and my blood pressure stayed the same as usual (low).

Today, I took 2.5mg. I'm... weird? I'm nauseous, and I really want to lie down but I know that I can't. My blood pressure is lower than usual (high 80s over high 50s).

Is this, like... normal? I thought it was supposed to work immediately. (I'm talking to a doctor soon for actual medical advice, but they usually leave out side effects and stuff ;-;)

I know a lot of us also have MCAS, so I wanted to ask here.

POTS doctor suspects that I have MCAS, so she's having me trial some meds for it. I've been on Claritin for years, so I'm keeping that as normal, but she asked me to add an H2 blocker.

My

I tried famotidine, but it caused severe fatigue, so I stopped it. She recommended cimetidine next, so I'm taking that now... but it's making me feel stupid. Words aren't coming to mind as easily and I keep getting mixed up on things I'm trying to say, it's like having a POTS flareup but only with mental symptoms. When I looked it up, it seemed like this might be a serious side effect, but my kidneys are fine and this seemed like an issue mostly for people with kidney problems or older people, so I'm not sure why I'd be having this. It's somewhat worrying.

Has this happened to anyone else? I'm just not sure if this is something others have experienced normally or not.

My POTS doctor suspects that I have MCAS, so she's having me trial some meds for it. I've been on Claritin for years, so I'm keeping that as normal, but she asked me to add an H2 blocker.

I tried famotidine, but it caused severe fatigue, so I stopped it. She recommended cimetidine next, so I'm taking that now... but it's making me feel stupid. Words aren't coming to mind as easily and I keep getting mixed up on things I'm trying to say, it's like having a POTS flareup but only with mental symptoms.

Has this happened to anyone else? When I looked it up, it seemed like this might be a serious side effect, but my kidneys are fine AFAIK and "confusion" is mostly listed for people who are old / have kidney problems, so I'm not sure why I'd be having this. It's somewhat worrying.