u/Fabulous-Quiet-3832

All 23 eggs retrieved are dysmorphic!

We (35F and 38M) went to a reputable clinic for ivf with unexplained infertility after 2 failed IUI and trying to conceive for more than a year. Got a good response to stimulation with Menopur (mix 2ml, draw 1ml) and Gonal F (287.5 first 3 days, decreased to 225 rest of the cycle). 23 eggs were retrieved. However, the next day we were told that all eggs were dysmorphic/degenerated. Lab reassured they followed their standard protocol and that lab processes were not at fault during or after retrieval. Normal karyotype and no significant family history of infertility. Repeat mini ivf retrieval with letrozole and minimal stimulation resulted in 2-4 eggs but same results. Clinic says this is genetic and success is only possible with donor eggs. Getting second opinion and looking for ideas if someone faced a similar situation. Please check additional details below.

Duration of stimulation first retrieval = 14 days

Estradiol (on trigger day) = 3246

Trigger shot first retrieval = lupron + hcg

Lead follicle size at first retrieval=21mm

Trigger to retrieval duration = 37 hours

Trigger shot second retrieval = omnitrope and lupron

Trigger to second retrieval duration = 35 hours

reddit.com
u/Fabulous-Quiet-3832 — 9 days ago

All 23 eggs retrieved are dysmorphic!

We (35F and 38M) went to a reputable clinic for ivf with unexplained infertility after 2 failed IUI and trying to conceive for more than a year. Got a good response to stimulation with Menopur (mix 2ml, draw 1ml) and Gonal F (287.5 first 3 days, decreased to 225 rest of the cycle). 23 eggs were retrieved. However, the next day we were told that all eggs were dysmorphic/degenerated (see image). Lab reassured they followed their standard protocol and that lab processes were not at fault during or after retrieval. Normal karyotype and no significant family history of infertility. Repeat mini ivf retrieval with letrozole and minimal stimulation resulted in 2-4 eggs but same results. Clinic says this is genetic and success is only possible with donor eggs. Getting second opinion and looking for ideas if someone faced a similar situation. Please check additional details below.

Duration of stimulation first retrieval = 14 days

Estradiol (on trigger day) = 3246

Trigger shot first retrieval = lupron + hcg

Size of lead follicle at first retrieval = 21mm

Trigger to retrieval duration = 37 hours

Trigger shot second retrieval = omnitrope and lupron

Trigger to second retrieval duration = 35 hours

u/Fabulous-Quiet-3832 — 9 days ago
▲ 2 r/IVF

All 23 eggs retrieved are dysmorphic!

We (35F and 38M) went to a reputable clinic for ivf with unexplained infertility after 2 failed IUI and trying to conceive for more than a year. Got a good response to stimulation with Menopur (mix 2ml, draw 1ml) and Gonal F (287.5 first 3 days, decreased to 225 rest of the cycle). 23 eggs were retrieved. However, the next day we were told that all eggs were dysmorphic/degenerated. Lab reassured they followed their standard protocol and that lab processes were not at fault during or after retrieval. Normal karyotype and no significant family history of infertility. Repeat mini ivf retrieval with letrozole and minimal stimulation resulted in 2-4 eggs but same results. Clinic says this is genetic and success is only possible with donor eggs. Getting second opinion and looking for ideas if someone faced a similar situation. Please check additional details below.

Duration of stimulation first retrieval = 14 days

Estradiol (on trigger day) = 3246

Trigger shot first retrieval = lupron + hcg

Trigger to retrieval duration = 37 hours

Lead follicle size = 21mm

Trigger shot second retrieval = omnitrope and lupron

Trigger to second retrieval duration = 35 hours

reddit.com
u/Fabulous-Quiet-3832 — 9 days ago