![Image 1 — [UPDATE] 6 weeks in: Retatrutide + CJC-1295 (no DAC)/Ipamorelin — body recomp progress + the appetite thing nobody prepared me for](https://preview.redd.it/jepyif4h9obh1.jpg?width=2000&format=pjpg&auto=webp&s=784928cfe86a91ea8045b84f9a89c25d2c2d5348)
![Image 2 — [UPDATE] 6 weeks in: Retatrutide + CJC-1295 (no DAC)/Ipamorelin — body recomp progress + the appetite thing nobody prepared me for](https://preview.redd.it/mumgqe4h9obh1.jpg?width=1179&format=pjpg&auto=webp&s=5bbba6a3cf38b99e1f3bff0133a60159b0f5496d)
[UPDATE] 6 weeks in: Retatrutide + CJC-1295 (no DAC)/Ipamorelin — body recomp progress + the appetite thing nobody prepared me for
Physician here, self-administering and tracking labs along the way. Sharing numbers + honest experience.
Protocol:
• Retatrutide: started 1.5mg/week (5/25), currently at 4mg/week
• CJC-1295 (no DAC) + Ipamorelin: 300mcg, Mon–Fri, before bed
• Resistance training 5x/week + 30min low-intensity fasted cardio post-workout
• Eating window: 12pm–6pm (~6h), protein-forward first meal at noon, whey shake at 6pm
• Daily intake: 800–1200 kcal, ~1–1.6g/kg protein
Numbers:
Day 1 (5/25) ————Now (6 wks)
Weight 97.7 kg ———————89.3 kg
Fat mass 30.6 kg (31.3%)——23.6 kg (26.4%)
Muscle mass 39.8 kg ———- 38.4 kg
−8.4 kg total, −7.0 kg fat, −1.4 kg muscle. Roughly a 5:1 fat-to-muscle loss ratio, which I’m
happy with given how aggressive the deficit has been.
What surprised me most: The food noise is just… gone. Not “under control” — gone. The
anxiety/craving loop around eating that used to sabotage every diet I tried isn’t there
anymore. I eat because I need to protect muscle mass, not because I’m hungry or anxious.
No fighting cravings for sugar or carbs, no “cheating,” none of the emotional labor dieting
usually costs me. Ironically I eat healthier now and enjoy it more, because the decision-
making is rational instead of driven by appetite.
CJC/Ipa’s contribution seems to be mostly sleep — noticeably deeper and longer, which I
think is helping the recomp side more than I expected.
Progress pics (day 1 vs now) attached.
Labs at week 4-5 (fasted panel):
• Fasting glucose 4.2 mmol/L, HbA1c 4.9% — excellent, no signs of insulin resistance
• Fasting insulin 2.3 mIU/L (ref 2.6-24.9) — actually below range, reflecting how insulin-sensitive this combo makes you
• Lipids clean across the board: total cholesterol 3.93 mmol/L, LDL 2.36, HDL 1.11, triglycerides 0.81 mmol/L
• Thyroid panel euthyroid (TSH 4.05, FT3/FT4 normal), thyroid antibodies negative — no autoimmune flags
• Liver enzymes normal, kidney function within range
• Vitamin D sufficient, B12 elevated (expected — I supplement methylcobalamin injections)
• Total testosterone mid-range normal
• Mild low-normal WBC/neutrophil count, rechecking next panel just to trend it
Nothing alarming, and honestly reassuring given how aggressive the deficit has been.
Happy to answer questions on dosing, timing, or labs.