u/Frequent-Arachnid547

Junko Enoshima (Dangaronpa)

Ragyo Kiryuin (Kill la kill)

Bernkastel (Umineko)

Eggchan: Dude are you broke or am I just worth nothing.

I burst out laughing when Theo said (with no ill intent) "who is Arachnid?" in minute 1:05:29. It shows how much of a joke he is to the point that the only reason they are a threat is because of them possessing Wemmbu.

The Invisible Mafia or The Law?

Both came very close to conquering the server, both had very elite players working for them, both forced the protagonists and several others to work together to take them down, both had immensly intelligent leaders, both heavily impacted the server after their fall.

Kamijou Touma: Was severly mistreated by other people due to his Imagine Braker atracting misfortune with only with his parents as support to the point that people actively tried to kill him. The mistreatment got so bad his parents were forced to send him to Academy City in an attempt to give him a better live though he would still be forced to endure Misfortune and would lose his memories several times.

Index Librorum Prohibitorum: Was abused by Necesarius magicians due to her magical knowledge which lead her being treated as more of a weapon than a person and constantly lost her memories once every year causing her to lose any relations she may have had until the present day.

Aleister Crowley: Was mistreated by everyone from strangers to his own parents for not being religious and when he finally found a group he belonged to, they betrayed him by indirectly causing his future daughters death and ended up being cursed himself with repeated failure and Misfortune.

Accelerator: Never new love as he was heavily experimented on from a young age and due to his immense power, never had any friends either as they all either feared him or hated him due to him being the strongest esper which lead to him living a life of solitude.

Fraulein Kreutune: An immortal being who lived for hundreds of years and could never make friends due to not being really "human" and was constantly hunted by the magic side due to her nature until she was captured by the science side and locked inside the windowless building where she would stay trapped for many years.

Shokuhou Misaki: Lost her best friend at a young age and lived a constant life of Mistrust due to everyone targeting her for her power and ended losing the only person she had a real relationship with after an attempted assasination on her, and while he lived, he could no longer form memories of her.

Mitsuari Ayu: Was repeatedly called inferior in comparison to Misaki which caused her to lose all her friends after being kicked from the lab which lead to her attempting suicide after the only friend she had left failed to save her which lead to her going insane.

Senior: Was constantly abused and bullied as a child for her abilities until she was taken to Academy City where her powers would slowly begin to cripple her and in the end, left her as nothing more than a metallic cube that was manipulated by Unabara into desiring revenge (though she could still use her abilities and posses others).