Tretinoin and possible deleterious health outcomes?

Tretinoin and possible deleterious health outcomes?

I have been using tretinoin for about 6 months now. While it has helped my acne, I have significant worries about the BHT in the formulation as well as the actually substance itself.
A quote from biologist Ray Peat.  "Yes, vitamin A and estrogen are antagonistic, and while estrogen promotes keratinization (shedding of skin cells), vitamin A opposes it. Since vitamin A is highly unsaturated, in excess it suppresses the thyroid, so it has to be balanced with the thyroid; the combination is effective for increasing progesterone and decreasing estrogen, slowing the turnover of skin cells, and making the skin cells function longer before flaking off. "
https://ahrp.org/excess-deaths-in-va-tretinoin-retin-a-trial_fda-silent/
While tretinoin is praised for the effects on the skin, could there be other possible side effects? I am planning on switching to a tazarotene cream without BHT and going from there. I am strongly against accutane as its effects on the liver are concerning, but I had always thought topicals were fairly safe until now. Thoughts?

u/LactoseTolerant22 — 1 day ago

WHAT DO I DO ABOUT MENINGOCOCKAL VACCINE?

So my highschool in VA will force me to get this dogshit gay ass meningocockal vaccine before I go into senior year. I want to get a form to get exemption but my church is cucked and my parents are the most fluoride stare ass liberals in the world. I have a couple years before this but I might need to emancipate myself before this. Maybe they won't notice lol.

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u/LactoseTolerant22 — 1 day ago

How bad are "natural flavors"

I was at my friends house and we were having a sleepover, I was getting deathly thirsty since I didn't bring good water and I had biked over in the summer heat. I drink a can of Waterloo sparkling water. Its reverse osmosis filtered fluoride and pfas free so good on that end. (though mineral content could be better) but it had 0 sugar, 0 artificial flavors, 0 cal, and it had "natural flavors" its non GMO so that's good but I worry about how bad the extraction method is.

In general too, how bad is it to moderately cheat if you are super hungry or thirsty? I don't mean McDonald's, but drinking pasteurized milk or eating too many oranges/pineapple for hydration.

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u/LactoseTolerant22 — 10 days ago
▲ 3 r/RawMeat+1 crossposts

Tretinoin and hormones

I have been on the diet for about 8 months now, and I started using tretinoin in late January because I got fed up with my acne. It worked well and now my acne is way less apparent. Over the past 2 weeks I started ramping up how much I used, since I only was using 0.025, to try to get the remaining acne I had to disappear. Over the past couple weeks I have been noticing a lack of morning wood and sometimes brain fog.
I was able to find a couple studies about this
https://pmc.ncbi.nlm.nih.gov/articles/PMC8207225/
https://pubmed.ncbi.nlm.nih.gov/36303869/ (this one is about thyroid)
Should I just stop the use completely? I don't use any sunscreen with it, trying to keep at least somewhat primal, but I do like what it's done to my skin.
I don't use accutane. Only topical tretinoin.

u/LactoseTolerant22 — 16 days ago

Low quality raw milk

Raw milk is illegal in my state except through herdshares, (so called freedom in the one of the founding states of America) so I got an offer to get paid in raw milk from some people outside of my neighborhood that have 3 pregnant goats. They gave birth recently and their kids are being weened. They wanted someone to milk them. These goats are given hay as food though, and possibly corn. The owners are old folks and probably give the goats medications and vaccines. Personally I think it is better than nothing, and since I will be milking them I don't have to wash the udder with things such as iodine. More bacteria, better milk.

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u/LactoseTolerant22 — 17 days ago

Need advice about Covid-19 jabs.

Over the past 6 months I have been looking greatly into the effects of the sars-cov-2 bioweapon and its corresponding injection. My mother has been severely injured by both of these, from infections and the jab itself. She has developed extreme dizziness, brain fog, and things such as POTS. I myself took the jab and a booster in 2022. I was young at the first time, so I got a half dose. Either way, I myself have been having brain fog, and am worried about my IQ decreasing from this, as I was quite gifted as a child. Most importantly, I need advice from someone who has a spiritual understanding of this. I have been reading into what King Solomon says on org. Things such as the mark of the beast, destruction of spiritual connections. My family has always been one that experienced odd things. My dad has had numerous OBEs. How should I go about recovering my health and rightful spirituality? Should I consider eating large amounts of unripe pineapple for the bromelain? High meat? Moldy berries? Or even forms of meditation and manifestation?

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u/LactoseTolerant22 — 20 days ago