6 days on Bupropion and feeling very depressed—is this normal?
It’s been six days since I started taking bupropion, and this week has been really hard; I feel more depressed... Everything feels meaningless, and I just want to stay in bed, hiding from the world. My doctor prescribed 150 mg of bupropion, and I was already taking 50 mg of sertraline. I’d like to know if this is normal—is it just the adjustment period? I’ve never felt such sadness as I have this week, along with a terrible mood and fits of rage.