Federal funds can't be used to give test strips to drug users, raising overdose fears

The Trump administration's Substance Abuse and Mental Health Administration (SAMHA) has prohibited use of Federal funds for harm reduction programs used to reduce death from illegal drug abuse. The city of Baltimore's Harm Reduction Coalition previously had a program to distribute test strips that would indicate the presence of dangerous adulterants in drugs that a user intended to use.

SAMHA's justification for this action was their current focus on distribution of overdose reversal agents such as naloxone (which is an antidote for opioids). However this does not take two facts into account: (1) Naloxone administered in the field is not a "miracle drug" because its duration of action is shorter than that of some long-acting opioids; and (2) not all drug abuse is opioid abuse. In this case the test strips were for a benzodiazepine adulterant that would not be affected if a victim subsequently took naloxone.

Advocates worry as government limits drug test strip funding : NPR

u/Nerd-19958 — 9 days ago
▲ 546 r/medicine

AAP Statement in Response to Executive Order on Vaccines

The American Academy of Pediatrics has issued a press release (linked below) warning of the dangers of President Trump's "executive order" stating Trump's opinion on recommended pediatric vaccine coverage and timing. Trump has no authority to set vaccine policy.

AAP stated in part:

>“Today's executive order is not based on "gold-standard science." There is no new evidence to justify significant changes to childhood immunization guidance. Dozens of studies involving millions of people show there is no link between vaccines and autism, and yet federal leaders continue to promote this outdated, disproven idea to scare families. Today's executive order will do nothing to support families of children with autism or advance understanding of the condition. The only purpose of this announcement is to sow confusion so that more people doubt the importance of vaccines. Delaying or skipping shots is risky, especially as measles continues to spread and children go back to school. 

https://www.aap.org/en/news-room/news-releases/aap/2026/aap-statement-in-response-to-executive-order-on-vaccines/

reddit.com
u/Nerd-19958 — 9 days ago
▲ 159 r/medicine

AMA statement on executive order changing childhood vaccine schedule

AMA issued a brief press release pointing out the dangers of President Trump's recent "executive order" transmitting his vaccine recommendations (for which he has zero authority).

>AMA stated in part: "Altering a proven vaccination schedule without credible evidence risks weakening public confidence and putting children’s health at risk."

https://www.ama-assn.org/press-center/ama-press-releases/ama-statement-executive-order-changing-childhood-vaccine-schedule

u/Nerd-19958 — 9 days ago
▲ 184 r/medicine

Moderna Receives U.S. FDA Approval for Influenza Vaccine mFLUSIVA

Moderna's mRNA-based influenza vaccine was recently approved by FDA for adults 50 through 64 years of age. Its indication for persons 65 years of age and older is under accelerated approval (pending confirmatory trial).

Per the prescribing information, this new vaccine encodes for the full-length HA glycoproteins of the 3 influenza virus strains represented in the vaccine. After delivery into cells, the mRNA serves as a template for the synthesis of the intended proteins.

This is noteworthy due to the Trump administration's previous defunding of mRNA vaccine research, and Secretary of HHS Robert F. Kennedy Jr's adversarial approach to vaccines, particularly those which are mRNA-based.

https://feeds.issuerdirect.com/news-release.html?newsid=4801915282452025&symbol=MRNA

reddit.com
u/Nerd-19958 — 14 days ago

Why There's a Shortage of Chemotherapy Drugs

One major general reason for generic drug shortages is oligopsony; a relatively small number of purchasers (wholesalers) and pharmacy benefit managers exert price-depressing market power over manufacturers. I know of instances in which a wholesaler required a retroactive price cut on product already in their inventory due to a lower price offered by a competing manufacturer, otherwise the wholesaler would have returned their entire inventory to the original manufacturer. [Which would have been a write-off because returned goods cannot be resold unless the manufacturer can assure they were stored and handled under proper conditions.]

The article is substantially correct except in the statement that the oncology drug manufacturer can simply switch to manufacturing other drugs (rather than the unprofitable ones) in the same plant. Cytotoxic drugs require specialized plants to minimize cross-contamination and exposure to employees.

https://time.com/article/2026/08/04/chemotherapy-drug-shortage/

u/Nerd-19958 — 16 days ago

FDA Approves First Nonprescription Fixed-Dose Combination of Acetaminophen and Naproxen Sodium

See link to announcement from FDA Center for Drug Evaluation and Research Small Business and Industry Assistance.

I am posting to request opinions from physicians and other readers of this sub, regarding whether combining acetaminophen with an NSAID is a rational combination, especially for OTC use? To the best of my knowledge acetaminophen is typically recommended for patients who are allergic to or intolerant of NSAIDS.

THANK YOU FOR YOUR ATTENTION TO THIS MATTER.

https://content.govdelivery.com/accounts/USFDA/bulletins/421f901?reqfrom=share

reddit.com
u/Nerd-19958 — 25 days ago
▲ 25 r/Tariffs+2 crossposts

How Donald Trump's tariff announcement impacts Indian Pharma companies

See link to CNBC-TV18 article reporting that US President Donald Trump claimed in a social media post, that import tariffs on Indian generic drugs would begin on 1 August 2028 starting at 100% and be raised to 200% on 1 August 2029. Trump will not be US President after 20 Jan. 2029. Based on his history of reversing positions, Trump might change this plan tomorrow if not sooner.

https://www.cnbctv18.com/market/sun-pharma-lupin-cipla-biocon-share-price-donald-trump-generic-drugs-tariffs-timeline-impact-19950953.htm

u/Nerd-19958 — 28 days ago

Arthroscopic Partial Meniscectomy for Degenerative Tear — 10-Year Outcomes

See link to April 2026 NEJM Correspondence reporting 10-year follow-up of a multicenter, randomized, sham-surgery-controlled trial of arthroscopic partial meniscectomy for degenerative medial meniscal tear in adults without radiographic evidence of established osteoarthritis.

The authors reported no evidence of benefit from the procedure, with a suggestion of worse outcomes after arthroscopic partial meniscectomy than after sham surgery. 

As a lay person, I am posting this link because in my personal experience everyone I know of who had knee surgery (I don't know the specific diagnoses, only the outcomes) ended up at best, no better than prior to surgery. I was diagnosed with torn meniscus about 8 years ago, and the specialist recommended surgery, which I refused. Instead I wore compression bands around both knees for several months, and eventually the pain ceased, never to return.

https://www.nejm.org/doi/full/10.1056/NEJMc2516079

reddit.com
u/Nerd-19958 — 29 days ago