▲ 2 r/Testosterone+1 crossposts

Anyone come off TRT after several years despite having high natural T before starting?

I’m 56 and have been on TRT for almost 4 years. Before starting at 52, my natural total T was 900–1,000 ng/dL, SHBG was very high (high 80s/90s), and free T was ~10.7 ng/dL. Despite those numbers, I had low libido/erections, low energy and had lost my drive for the gym.

I spent the first few years trying different TRT protocols. For the last year I’ve been on daily subQ (~85–90 mg/week), and it’s the first protocol that has consistently maintained my libido and erections. Current labs are generally total T ~1,100, SHBG in the 50s and E2 ~25.

But I’m questioning whether I want or need to stay on TRT indefinitely given that my natural T was so high before starting.

I’m especially interested in anyone who had normal/high T before TRT and came off after several years. Did your natural production eventually recover close to baseline? How rough was the transition? Cold turkey vs. a medically supervised restart/PCT? And did you ultimately stay off or go back on?

Separate question: I’ve also developed mild-to-moderate sleep apnea over the last year. If anyone actually saw their AHI/OSA improve after stopping TRT, I’d be interested in hearing about that too.

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u/Objective-Pen7633 — 7 days ago

Why is AI constantly wrong lately?

Claude and Gemini are maddening. Last several weeks im always yelling at them for not recalling something we just talked about, forgetting a document I uploaded 3 times, constantly telling me its sorry for misleading me with wrong information when i was right on every point, giving completely wrong information then telling me I had it backwards. I dont see the point anymore in using Al!

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u/Objective-Pen7633 — 1 month ago

Oral and injectable same time?

So in doing my research on BPC I’m having significant gut issues as well as multiple pain issues from occipital nerve in my neck to knee pain that came back three years after knee surgery to lower back pain and radiating over to the hip and sciatic nerve.

Doing some deep dive with Claude AI, the recommendation was to go with both oral and injectable BPC at the same time to knock out the significant gut issues as well as dealing with the multiple pain points throughout my body.

Has anyone take them both together and any concern about side effects doing both together and any thoughts or comments in general?

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u/Objective-Pen7633 — 3 months ago