Persistent microscopic blood in urine and pathological casts on two urine tests, normal creatinine. What should my next step be?
Hi everyone,
I’m a 27-year-old male.
I had a routine health check. At the time of my first urine test, I had a cold with a mild fever.
My first urine test showed:
Protein +
Blood present
RBCs 4–6/HPF
Pathological casts present
I repeated the urine test, and it showed:
Protein improved to trace
Blood still present
RBCs still 4–6/HPF
Pathological casts still present
Other relevant information:
Serum creatinine: 1.2 mg/dL (normal)
Blood urea: 64.4 mg/dL (mildly elevated)
HbA1c: 5.3%
Blood pressure is normal.
I have no burning while urinating, no visible blood in urine, no flank pain, and no swelling.
I do notice persistent foamy/bubbly urine.
For the last 3–4 days, I’ve also had a continuous burning sensation in my upper stomach. A doctor thought it was acidity but didn’t really review my urine reports.
My questions are:
Could a cold with a mild fever explain these urine findings, even though they persisted on a repeat test?
How significant is “pathological casts” when the lab doesn’t specify the type?
What would be the appropriate next investigations? (
Does this sound urgent, or is it reasonablen to wait