u/Ornery-Anxiety4452

35M, 6ft/95kg, been on BP meds for a while (ARB + thiazide diuretic + beta-blocker + CCB combo). Recent labs:

\*\*•\*\*	eGFR: 81-88 (standard reported range, normal, stable across two tests months apart)    
\*\*•\*\*	BSA-adjusted eGFR: worked out to \\\~103 mL/min once corrected for my actual body size (I’m bigger than the “average” 1.73m² the formula assumes) — so likely even better than the standard number suggests    
\*\*•\*\*	Urine ACR: 10 (normal, under 30)    
\*\*•\*\*	Urine dipstick: trace protein positive — twice, months apart    
\*\*•\*\*	Uric acid: 7.06 → 8.5 mg/dL (trending up, above range)    
\*\*•\*\*	Triglycerides: 245 → 304 mg/dL (also trending up)    
\*\*•\*\*	HDL: dropped to 28 (low)    
\*\*•\*\*	BMI: \\\~28 (overweight)    
\*\*•\*\*	Kidney ultrasound/Doppler: completely normal

Doctor says kidneys look structurally fine and ACR is reassuring, but wants to keep an eye on the trace protein + uric acid combo since it showed up twice.

Anyone dealt with something similar — persistent trace proteinuria with otherwise normal ACR/eGFR while on BP meds? Did tightening BP control, diet changes, or a med switch (thiazide diuretics are known to raise uric acid) make a difference for you? Also curious if anyone’s doctor treated the uric acid directly even without gout symptoms, or if anyone else has looked into BSA-adjusted eGFR for a more individualized read.

Not looking for diagnosis, just curious about others’ experience before my next follow-u

35M, 6ft/95kg, been on BP meds for a while (ARB + thiazide diuretic + beta-blocker + CCB combo). Recent labs:

**•**	eGFR: 81-88 (standard reported range, normal, stable across two tests months apart)  
**•**	BSA-adjusted eGFR: worked out to \~103 mL/min once corrected for my actual body size (I’m bigger than the “average” 1.73m² the formula assumes) — so likely even better than the standard number suggests  
**•**	Urine ACR: 10 (normal, under 30)  
**•**	Urine dipstick: trace protein positive — twice, months apart  
**•**	Uric acid: 7.06 → 8.5 mg/dL (trending up, above range)  
**•**	Triglycerides: 245 → 304 mg/dL (also trending up)  
**•**	HDL: dropped to 28 (low)  
**•**	BMI: \~28 (overweight)  
**•**	Kidney ultrasound/Doppler: completely normal

Doctor says kidneys look structurally fine and ACR is reassuring, but wants to keep an eye on the trace protein + uric acid combo since it showed up twice.

Anyone dealt with something similar — persistent trace proteinuria with otherwise normal ACR/eGFR while on BP meds? Did tightening BP control, diet changes, or a med switch (thiazide diuretics are known to raise uric acid) make a difference for you? Also curious if anyone’s doctor treated the uric acid directly even without gout symptoms, or if anyone else has looked into BSA-adjusted eGFR for a more individualized read

35M, 6ft/95kg, been on BP meds for a while (ARB + thiazide diuretic + beta-blocker + CCB combo). Recent labs:

**•**	eGFR: 81-88 (standard reported range, normal, stable across two tests months apart)  
**•**	BSA-adjusted eGFR: worked out to \~103 mL/min once corrected for my actual body size (I’m bigger than the “average” 1.73m² the formula assumes) — so likely even better than the standard number suggests  
**•**	Urine ACR: 10 (normal, under 30)  
**•**	Urine dipstick: trace protein positive — twice, months apart  
**•**	Uric acid: 7.06 → 8.5 mg/dL (trending up, above range)  
**•**	Triglycerides: 245 → 304 mg/dL (also trending up)  
**•**	HDL: dropped to 28 (low)  
**•**	BMI: \~28 (overweight)  
**•**	Kidney ultrasound/Doppler: completely normal

Doctor says kidneys look structurally fine and ACR is reassuring, but wants to keep an eye on the trace protein + uric acid combo since it showed up twice.

Anyone dealt with something similar — persistent trace proteinuria with otherwise normal ACR/eGFR while on BP meds? Did tightening BP control, diet changes, or a med switch (thiazide diuretics are known to raise uric acid) make a difference for you? Also curious if anyone’s doctor treated the uric acid directly even without gout symptoms, or if anyone else has looked into BSA-adjusted eGFR for a more individualized read.

Not looking for diagnosis, just curious about others’ experience before my next follow-u

Hey everyone, looking to see if others have cracked the code on this.
I’m 35 and have strong genetic hypertension. No structural blockages or hardened arteries, but my nervous system just loves to keep my blood vessels squeezed tight. Because of it, my doctor has me on a heavy 4-medication regimen: Telmisartan, Amlodipine, Chlorthalidone (diuretic), and Bisoprolol (beta-blocker).
Recently, I started practicing strict abdominal (diaphragmatic) breathing to try and stimulate my vagus nerve to override that "fight-or-flight" vascular tightness.
I just clocked a lifetime low of 115/74 mmHg right after a session.
The fact that it drops this low proves the blood vessels are perfectly elastic and clean—they are just functionally clamped down by stress/genetics. I’m currently pairing this breathing with heavy hydration (2.5–3L of water to counteract the Chlorthalidone drying out my kidneys) and working to lower my triglycerides (245 mg/dL) to clear out any arterial stiffness.
My goal is to train myself to belly-breathe on autopilot so this 115/74 baseline becomes permanent, allowing my cardiologist to taper me down from these 4 drugs.
Has anyone else with genetic hypertension successfully used deep breathing to permanently lower their baseline or reduce their medication load? What was your timeline like?

I am planning to apply for internal job posting for London position in data science. How much salary should I expect currently a VP with 10 + yoe.

I am lead data science with 13 year of experience in a leading bank have prior experience in building risk models and trading models. Does doing FRM gives benefit for in terms of future job and international movements