Since Blood Meridian is unfilmable...
How about Bloody Medium?
It's a dreary tale of cosmic hunger, universal vore in which the skinny-fat kid joins a gang of fat women on a quest to win every eating competition in the world.
It starts harmless enough with the gang celebrating each win by ravaging nearby buffets and roadside diners, but after Judge Hollandaise (7 ft albino Male To Fester beast) makes his infamous speech about cosmic vore, the gang starts to eat men.
In the end, Judge Hollandaise eats everyone in the gang except the not-so-skinny-fat kid. Judge gives the kid an ultimatum - to transition or to be eaten. Kid refuses to wear a wig and a dress and is eaten by the Judge.
Final scene. Judge is driving around Disney land giggling to himself.
Someone call Fincher, tell him I'm ready when he is.