u/Some-Comedian-264

Average read depth on chromosomes 1-22 was 42X for me (mother) and average read depth on chromosomes 1-22 for him (son) was 75X.

MT read depth for me was around 11,300X and for him it was around 16,400X.

We have a very high amount of NUMT’s and differ at 2 locations. Novel variants in certain genes must be beneficial and everything is balanced somehow because we are healthy, athletic and look younger than our ages.

For those that have expertise in this particular subject, I’d appreciate your feedback and/or opinions.

Discovered I’m an XXY female whose Y chromosome matches my sons Y 99.9%. I assumed microchimerism but from what I understand, it is impossible for 30X sequencing to detect a full Y chromosome (from son) and that you need 500X+ read depth to detect it. I’m physically female (inside and out) and perfectly fertile and have found autosomal variants that resulted in me being a healthy female. There are a lot of other interesting/novel findings as well. I’d appreciate any expertise and would be happy to answer any questions you may have and can provide more details.

(Update: I won’t be commenting further.. my plan is to do further testing).