r/DNA

My dad got his DNA results in today! We discovered he has a sister nobody knows about. After talking to my aunts, SURPRISE, it’s actually the woman my aunt donated bone marrow to when she was a child! My grandparents honor has been vindicated and my dad is relieved he doesn’t have to buy a birthday present for another sibling. Anybody hear of any interesting results like this?

Does anyone know where R-PH4769 and R-YP1456

They're mine and my cousins haplogroups someone had said both are tarim basin origin but I feel like only R-PH4769 is possible since it is R1b but I'm just unsure if either of them are tarim basin or where exactly they could be from or which group like the tianshan saka tasmola some other group

Hey everyone, I’ve been battling severe abdominal bloating and reflux for over 20 years, along with 10 years of varicose veins and a left varicocele. Lately, it crossed over into intense morning brain fog, fatigue, a cracked tongue, and zero morning wood. My labs show a steady downward slide in Ferritin at 54 and B12 at 308 since last year, even though I eat meat. My MD won't prescribe Rifaximin without proof, so I’m seeing a functional naturopath next week to finally run a clinical 3-gas breath test and map out my exact numbers.

To troubleshoot, I ran my 23andMe data through a StrateGene report and the dots connected perfectly. I have a slow PEMT gene causing sluggish bile, which allowed a massive Hydrogen and Methane overgrowth to take root and steal my nutrients. The constant abdominal gas pressure physically clamped down on my pelvic veins, explaining the 10 years of vascular pooling and stalled morning circulation. My brain and skin are equally hyper-reactive due to a fast BHMT methylation cycle but slow MAOA and COMT clearing pathways. Whole eggs or high-dose standard B12 trigger explosive whiteheads within 48 hours, and a recent trial of Thorne Phosphatidylcholine was a disaster, overloading my brain chemistry and causing a horrible mood crash within 5 days.

Right now, my FoodMarble AIRE 2 device shows a crazy shift. A 30-day trial of TUDCA completely flattened my methane line to zero and formed my stools, proving the methanogens are highly sensitive to bile flow. However, my hydrogen line stayed elevated and my bloating bounced right back when I ran out of TUDCA, meaning the underlying hydrogen-producing bacteria are still actively fermenting my food. To clear a clean baseline for my test next week, I've paused almost all supplements except daily morning Vitamin B2 for my MAOA gene, and California Gold ProDigest at bedtime to keep my gut motility moving safely without any skin or mood flare-ups.

If the breath test is positive next week, I’m proposing a phased clearing protocol to my naturopath. If my insurance covers it, Plan A is a 14-day course of Rifaximin paired with 4 weeks of Allimax Pro stabilized allicin and TUDCA at dinner, since Rifaximin requires active bile to dissolve and kill the bugs. If insurance denies it, Plan B is a 100% natural 4-week run swapping the Rifaximin for NOW brand Berberine capsules that I already have on my shelf. During this clear phase, I’ll maintain my morning B2 and switch my 3-year daily magnesium glycinate habit to Magnesium Malate 95mg caps to power my brain energy without over-fueling my skin breakouts. I’m holding off on any iron or B12 supplements for now because I want to trust my body to sort itself out. Once the gas is gone and I hand the long-term job over to bedtime ProDigest, my gut should naturally start absorbing nutrients from my food again. Anyone else approaching their overgrowth this way? Would love to hear your thoughts!

Just found out my baby is homozygous

Gene: WNT10A
Variant: c.682T>A (p.Phe228lle)
rsID: rs121908120

She’s only 6 months old. What should I expect? Is this a sign she will have some manifestation? Is Ancestry reliable?

Hello everyone;

I'd like to ask which service is better for DNA analysis:

DNA Complete by Nebula Genomics

SelfDecode

Sequencing

I've made a plan to first do DNA Complete with Nebula Genomics, then I'll get the raw data and upload it to SelfDecode so I get a better report, since Nebula Genomics uses 100x.

Im blue eyed, brunette (polish) but i might be dark blond in certain lighting and by hairdressers but most people would assume im brunette, my mom is light blond and theoretically my partner is blond, blue eyed. So it's usually 50/50 blond hair and 100% blue eyes right but is me having dark blond hair (or lighter brunette) increasing the chance of the kids having lighter blond or dark blond at least? Or still 50/50