Join me https://discord.gg/x9FzVjrud we are growing everyday

In this discord we help for free:

1. dig through genomic data
2. Gather lab data
3. Fill out FDA reports

ANYONE WHO IS CHARGING ANYTHING IN THERE IS NOT ENDORSED BY ME TO DO SO

In light of recent current events in the USA.Here are all the powerful drugs found in Lindsay Clancy’s system after she strangled her three kids SSRIs are becoming more heavily politicized. We need to use this to our advantage. Why do we not send out a mass email to every single U.S Congressman and Senator explaining to them that people are literally chemically castrating themselves and eating shit (fecal matter transplant) in an attempt to cure themselves of a disease caused by SSRIS of which there is absolutely no help for at all and of which no physician will take us seriously for. Of which we have a subreddit that has 18k weekly members 21k subscribers of sufferers.

Are you telling me that if I email 435 congress people and 100 senators that people are fucking castrating themselves to cure themselves of a disease induced by SSRIS of which a lady has already gone public on the White house floor about that not one of them will take action or reply back of which is RIGHT now in the public eye because of the Lindsey Clancey case. it's the perfect time to strike the nation

u/mobius1014 u/moderator u/pssdnetwork can the pssd network accomplish this. If the answer is no project genome will do it in a probably way less sophisticated way than you guys would. Im not taking no for an answer on this.

Yes I am well aware that this information is freely available scattered throughout the void. But when a lot of people say reinstatement they do not specify whether or not they went back on the drug that crashed them or a different drug entirely.

The difference matters because each of these drugs inhibit and induce different clearance enzymes. at different rates.

I’m currently on a 300mg per week testosterone cycle, and I’ve noticed ALOT of benefits from it in the first couple weeks with libido cognition and anheondia. But not it’s like all of the effects have dissipated, I may even feel worse than I did before while on it. But the weird thing is my body is still responding to androgens very well, I’m putting on size I’m getting stronger etc, so it’s not like PFS where my androgen receptors are working correctly in my muscles. But mentally I feel more brain fog, and I feel more blank minded. Does anyone know why this may be happening?

If Doctor Powers Theory is correct we should have a decent chunk of both of the above. I know we have a decent amount with Osteoperosis. But I am unsure how many are infertile. I looked up on the sub not much info.

On second thought Women too but I cant update the title

None of them give a fuck. For some reason. https://www.reddit.com/r/AskADoctor/s/2CZ9yT49KS

“Hey can you help treat post drug patients?”

FUCK YOU NEEDS AN RCT NEEDS A DOUBLE BLINDED PLACEBO.

Facing jesus level persecution every day. Its fucked

Edit: Medicine Jesus AKA Dr. Powers is not who i am talking about.

I’m 31 years old now, but I started about 10 years ago in summer of 2016 at 21 when I noticed my crown was thinning, Dr gave me a laser cap, minoxidil and 1mg finasteride, at first, I didn’t really notice anything bad, I knew all the horror stories online, but I still was able to function normally for years in fact,

No sides, lots of nights out with friends, girls, travel and a full head of hair, I figured I was one of the lucky ones, then some of my friends got the idea of doing sarms and I did a cycle in march of 2021 felt like King Kong for about a few weeks and built some nice muscles then … CRASH for about a month and a half. I felt like I was 80 years old, clomid did not seem to help, I recovered after this, but I never felt quite the same, I was more unstable now

Then i believe around early 2022 I stopped finasteride to see if I’d feel better, and man, felt like I was 18 again, I probably did have side effects all along diminishing my libido for all those years however instead of losing half or most of it I probably only lost 10 or 15% so it wasn’t very noticeable at first, who knows tho, but even after being off of it for a long time, I didn’t notice much hair loss

But then I did notice some, and in order to keep my hair I tried topical fin in the summer of 2023, same thing crash, I was down in colombia then and I bought probiotics which seemed to pick me up after I’d take some, along with eating red meat, figured I found the cure to bouncing back quick after stopping it

From that summer onwards, I really couldn’t handle sugar or carbohydrates without some sort of a crash, I continued to take very low dose topical mostly cause of YouTube hair channel’s promoting its safety, early 2025 I stopped, and then tried dutasteride last July. July 2025, crashed hard again but this time it took months to recover, tried topical dut late December 2025 from a doctors advice, and said enough is enough so did a 3 day water fast and ate clean as can be for a month or so and bounced back

Started pyrilutimide 1% this January and I can say it works better than fin like WAY better but I still have sides on and off, it seems as if the crashes are getting longer and harder for me, I often have zero libido, some brain fog, bad sleep, and physically, the testicles are smaller and the volume of semen is watery and “hot” feeling almost, like borderline painful

Wondering if pyrilutimide could also mess up my androgen receptors or if this is just ongoing damage from the dut/fin, I feel I can still recover decently if I go a week eating just meat and avoiding any sugar but this lifestyle is very hard for me to live, as I model, and my hair helps my livelihood in addition so do my muscles so the diet is a big problem

I know there are some here that are probably in way worse shape and I feel for you but just curious if anyone has something to add or experience with pyrilutimide or if anyone tried a libido enhancer like apomorphine

(I’d say I’m 4/10 right now side effects wise and I still get strong morning erections, I never rlly got ED symptoms but low libido absolutely

TL;DR

Developed PSSD after being prescribed Effexor/Venlafaxine for exam stress in college. Spent 7 years trying every supplement, protocol and specialist imaginable trying to fix it. Eventually decided to try TRT properly through a clinic in Thailand after reading success stories online.

Did around 8 months on TRT followed by a full PCT.

TRT improved gym performance, confidence and energy at times, but never truly restored libido or natural sexuality. The entire process ended up being way more psychologically intense than I expected. Hair shedding, agitation, feeling chemically “on”, then a brutal post-PCT crash where I basically slept for 6 weeks straight.

Now months off everything and still trying to get back to baseline.

Posting because there aren’t many detailed TRT → PCT → PSSD experiences online that talk honestly about the mental side of it.

___________________________________________________________________________________

Background

I’m 30 now.

Around 23 I got prescribed Venlafaxine/Effexor for anxiety/exam stress during college. Honestly at the time it helped a lot mentally, but almost immediately I noticed something felt wrong sexually.

Things became:

• muted
• disconnected
• less instinctive
• more “manual”

I kept bringing it up to my doctor and was constantly told:

• it would pass
• my body would adjust
• things would return after stopping the medication

I stayed on it around 9 months, came off expecting everything to bounce back, and it never really did.

Over the next 7 years I tried pretty much everything:

• Every natural supplement you can think of
• diets
• microbiome Transplant
• neurologists
• PRP, Shockwave Therapy
• endless Reddit rabbit holes

Nothing truly fixed it.

Eventually I became convinced the issue had to be hormonal after reading enough TRT/PSSD recovery stories online.

Australian doctors wouldn’t prescribe TRT for PSSD, so I went to Thailand and did it properly through a clinic instead of sourcing random gear online.

___________________________________________________________________________________

TRT Timeline

Month 1 — Starting TRT

Protocol:

• 75mg testosterone twice weekly

Honestly the first week was rough.

I barely slept for several nights and felt massively overstimulated. Trying to work while sleep deprived and injecting hormones into yourself after years of PSSD anxiety is mentally intense. I was overanalysing every sensation in my body wondering if I’d made a huge mistake.

By week 2 things settled:

• sleep improved
• motivation improved
• gym felt better
• mood felt more stable

Sexually though, nothing major had changed yet.

Month 2 — Honeymoon Phase

Dose increased to:

• 100mg twice weekly

This is where I thought:

>

I started getting:

• libido surges
• more energy
• more confidence
• stronger drive

For the first time in years I felt closer to actual sexuality again.

But the deeper PSSD symptoms still remained underneath it all. Desire improved more than genuine natural arousal/function.

Month 2–3 — Hair Shedding / Anxiety

This phase messed with me mentally.

Hair was suddenly everywhere:

• shower
• apartment floor
• keyboard
• gym mirrors

I could literally see my temples thinning.

When you already have PSSD and body anxiety, adding possible hair loss into the mix becomes incredibly stressful. I seriously questioned whether any of this was worth it.

The shedding eventually slowed down, but I do think TRT accelerated recession around my hairline thts still kind of noticable even when I have stopped everything.

Months 3–5 — Bigger, Stronger… But Different

Physically TRT definitely worked:

• gym performance improved massively
• gained ~10kg
• looked healthier
• stronger presence/confidence

But mentally I also changed in ways I didn’t expect.

I felt:

• more reactive
• more agitated
• more aggressive
• constantly slightly “wired”

It’s hard to describe but I never fully felt relaxed in my own body on TRT. Almost like there was this constant chemical intensity sitting underneath everything.

Friends/family definitely noticed changes too.

One weird thing:
alcohol started affecting me very differently around this time. I had several blackout drunk nights with almost no memory of what happened which honestly scared me alot .

Months 5–7 — Realising TRT Wasn’t Fixing PSSD

This was the hardest realisation.

By this point I had to admit:

• libido still wasn’t natural
• attraction still felt disconnected
• sexuality still felt “manual”
• PSSD wasn’t actually gone

TRT improved:

• physique
• gym performance
• confidence
• energy

But it never restored instinctive sexuality the way I hoped it would.

I also became exhausted by the TRT lifestyle itself:

• injections
• travelling with needles
• bloodwork
• planning everything around medication
• never feeling fully natural

Eventually I just wanted off.

___________________________________________________________________________________

Coming Off TRT

I went to an endocrinologist hoping for proper help with PCT.

Honestly it was useless.

The advice was basically:

• stop testosterone completely
• crash into hypogonadism
• retest in 4–6 weeks
• then maybe qualify for treatment

That started a panic trying to source proper PCT medication.

Eventually I found an online clinic and started:

• daily HCG (~6 weeks)
• Enclomiphene 12.5mg
• Pregnenolone 5mg

Later:

• increased to 25mg enclomiphene
• then tapered back down

PCT Experience

The early phase was terrifying.

I lost almost all sexual interest completely. Not just low libido, total disconnection from sexuality. It genuinely made me think I had permanently destroyed myself.

But weirdly emotionally I also started feeling calmer:

• less agitated
• less chemically “on”
• less overstimulated
• more like myself mentally

Then came coming off everything completely.

This was honestly the hardest phase of the entire journey.

For about 6 weeks my body basically shut down:

• sleeping constantly
• no motivation
• no drive
• no interest in socialising
• couldn’t gym properly
• brain felt blank

It didn’t even feel like emotional depression exactly. More like my nervous system had entered some kind of recovery/reboot mode.

Gradually things improved after that, but it took time.

Where I’m At Now

Months off everything:

• sexual function still not restored
• libido still disconnected/blunted
• still trying to get back to baseline

The biggest thing TRT taught me is that for me personally, this probably isn’t simply a testosterone problem.

It feels much more:

• neurological
• dopamine/reward-system related
• nervous-system based

I don’t fully regret trying TRT because at least now I know.

But I also think people massively underestimate how psychologically intense TRT + PCT can become, especially if you already have PSSD or nervous-system issues.

This was honestly one of the hardest years of my life mentally.

I want to thank the PSSD mods for accepting the criticism that we gave them. A couple months ago there was major concern about over moderation. In which someone made a post criticizing this. Since that time the over-moderation has gotten much much better. Its hard to be accountable and accept criticism but the PSSD mods did and for that I am grateful. I am also grateful they allow open theoretical discussion on this sub