Hi!
I'm on Duloxetine since 6 weeks ago, first 40 then 60. I'm still feeling down and want to cry: this is the 4th med and I'm tired.
In your experience, there is still hope that can work?
Thanks and sorry for my english!
Anyone have success with Cymbalta after failing SSRI’s? I have now tried both Zoloft and Lexapro and have not received relief. I have not tried SNRI’s yet and I think it’s time. I gave Zoloft a year , and I have been on Lexapro since January. I’m desperate for relief. *TW* I am suffering from horrific intrusive thoughts of death and suicide. They just don’t stop all day long and are truly ruining my quality of life. These thoughts are unwanted but are haunting me 24/7. Trying to narrow it down to Cymbalta or Effexor next.
I’m a bisexual woman and historically have had a preference for men. I tend to be strongly oriented to whatever gender my partner identifies as when I’m in a relationship, to the point where I will question my sexuality in either direction.
last time i dated a woman, I was on prozac. I took a few years off meds and now I’m on duloxetine and I’m starting to notice complete apathy towards men (romantically and sexually). i can’t help but notice a pattern here, but im not mad about it. has anyone else noticed a shift in their sexual orientation on meds vs off meds? I only had other sexual side effects when I first started meds, and 8 weeks in now i have a higher libido than before.
I’ve been taking this medication for a little more than 2 years now. My psychiatrist prescribed it to me to mainly help treat my agoraphobia and panic attacks.
It certainly has helped although I wouldn’t say I’m 100% cured of them but it has helped tremendously in dealing with them.
Well I decided to stop taking it a week ago after missing my dose for 2 days. It had already started to cross my mind to stop taking it for a while now.
I started to grow tired of the emotionally numb feeling towards everything and have been thinking about trying to live life again and deal with the anxiety and panic head on.
I feel like I’d be more capable now of dealing with it now given all the tools and things I’ve learned from my therapist and psychiatrist as. And seeing as my agoraphobia and anxiety are seemingly still present why not try to deal with them myself?
The emotional numbness isn’t the only reason for wanting to stop the medication though, I also suffer from hyperhidrosis which is excessive sweating.
Unfortunately for me it’s my whole body that sweats excessively and it seems like cymbalta makes it sooo much worse! Just being off of it for 1 week I feel like my sweating has been reduced by half. With summer coming up it is fucking hell dealing with the sweating.
But ever since like day 3 of quitting cold turkey I have been going through it…
Constant brain zaps, feeling very emotional, irritated and guilty suddenly, feeling derealization and detached, insane vivid dreams and nightmares, loss of motivation, nausea and other gi issues, body aches and headaches, fatigue and just an overall feeling of being back to where I was right before I started taking cymbalta.
I didn’t consult with my psychiatrist before doing this but I know ofc he’d most likely advise me not to do this.
Has anyone who quit cold turkey powered through this barrage of symptoms? Is it worth it fight through them and for how long do they go on?
I kinda feel like I fucked up big time and am worried that I’ll still feel like this even if I do return to taking it.
Any insight is greatly appreciated from anyone who’s dealt with this, thank you 🙂
So I've been off cymbalta for 1 month. I went from 40mg down to 20mg for 2 weeks then stopped. I had a lot of mild physical withdrawal symptoms. I felt off. Almost like I was walking on a boat. Nightmares, sleep disturbances, irritability ect. Most of that has went completely away but I have super horrible depression/anxiety. I cry daily. I'm overwhelmed. I do have a ton of things going on personally so idk if that is making it worse. I was on the cymbalta for pain, not any kind of depression. I know my vitamin D is very low as well as iron. Probably most of my vitamin levels are low honestly. I bought some good D3+k2, vitamin c plus zinc and B vitamins and iron. Is there anything more I can do? I hate my new dr and don't want to go see her and I couldn't afford a new prescription anyway.
I’ve started taking Duloxetine and I’m through the first week. From day one I experienced a bit of nausea and no appetite, but nothing I couldn’t handle. After 5 days, I’ve become really sick with nausea, sweating and a weird feeling in My head. I feel absolutely awful. I can read that many people experience this, but is there anyone who can tell me how long it lasted if they experienced something similar? I can’t work because of the nausea.
I’m taking it for anxiety, nerve pain, and to help me get off my use of Aspirin.
I finally after 5 months of being on 60mg of duloxetine I had 3ish really good days finally felt like I was getting better and now I’m back to side effects and feeling like garbage I don’t know what to do anymore
I don’t want to fear monger about cymbalta because it has helped me so much with my OCD and depression but I wanted to post this because it was unexpected and has been really inconvenient. And in case it might help anyone.
I’ve got some degree of hypermobile joints and it’s pretty mild but I’m quite prone to injury. Especially repetitive strain injury. I used to have a bad case of an RSI called plantar fasciitis, which affects a big piece of connective tissue that forms the arch of your foot. This was a long time before I went on cymbalta but it became chronic and was awful. But eventually with rest, rehab, better shoes, calf stretches and gradually increasing my activity it did go away
Anyway, fast forward about 8 years and I’m on cymbalta and working in a fairly active job. My foot starts feeling kinda funny but not sore. I decide to get it checked out just in case, my doctor sends me for a scan and they tell me I have plantar fasciitis again (it’s clearly visible on an ultrasound which is handy). Anyway, I don’t have any pain just slightly altered sensation so I don’t think much about it and my podiatrist says not to worry about it.
Fast forward another year and I’ve been walking a lot for exercise and mental health and suddenly my foot starts hurting pretty bad. Go for another scan and the plantar fasciitis has got worse.
I come off cymbalta and onto another antidepressant that isn’t a painkiller and the pain gets even worse. This is despite staying almost totally off my foot for several days, which last time would reduce the symptoms quite a lot. I think Cymbalta has definitely been masking the pain and has allowed me to walk a lot on an injured foot that needed rest and rehab.
Moral of the story I guess is that your allied health professionals should always be aware of your meds. And that we are on a medication that is a pretty powerful painkiller (for those on cymbalta for mental health reasons and not pain).
If I had caught this quickly it would not have got nearly so bad and be facing much quicker and simpler rehab
I just want to say I love this med. And I’ve lost weight on it!! I was terrified to try it.
( for anxiety & back pain )
Hi. My (27f) pyschiatrist just put me on 30mg duloxetine/Cymbalta. She wants me to start the medication immediately even though I’m currently on Effexor. She said that because I’m on Effexor 37.5mg that I can switch directly to Cymbalta 30 with no withdrawal effects but I forget the exact reason why she explained it to me.
She also said that I should take the medication when I wake up with my 10 mg IR Dextroamphetamine/adderall for adhd but I am scared to take it when I wake up because on the bottle it says it causes fatigue — also the bottle doesn’t specify to take it in the morning, it just says to take it once a day. So I would personally feel more comfortable taking it at night. But at the same time I’m worried about insomnia. So I’m not sure what is best? On top of this I have also been experiencing insomnia the last few weeks and I am not sure if it because of my adhd medication (she has been trying different medication on me besides adderall including Focalin, Vyvanse and Concerta) or the Venlafexine.
Thank you for any advice!
I just kinda want to share how I feel right now no point in this post really but anyways I been on 60 mg on duloxetine for 4 or 5 months now and it was horrible for a while side effects all the time extreme fatigue but 3 days ago I suddenly just felt so good and it’s continued for 3 days I been trying not to jinx it haha but my brain is like too active and doesn’t know how to feel about it if that makes sense I had crippling anxiety and panic attacks for 9 months now like can’t leave the house debilitating and it’s like my brain can’t realize that my body finally feels normal for once I don’t really know how to explain it if anyone sees this sorry for wasting your time haha I just feel so good and my brain don’t know how to handle it and wanted it to put it out there somewhere because I have no one to talk to that understand how bad anxiety and panic attacks are
hi reddit, i've been prescribed duloxetine to help with chronic pain and fibromyalgia symptoms. i'm on my first day of 50mg but have been signed off work for the last week cos i just feel so fatigued, i have lost all my motivation to do anything and also have ADHD so that doesn't help. i'm crashing out at 4pm but can't sleep at night. i haven't really had any bad symptoms otherwise, i can't say it's helped my pain that much but it's definitely made me overall happier so i'm noticing it a bit less. i live in the UK and was wondering if it's worth asking my private prescriber if he can prescribe wellbutrin alongside duloxetine? how do other people combat the fatigue? i already have chronic fatigue so it's really not welcome!
Hi!
I’ve come across several comments from people saying that this medication definitely causes excessive weight gain.
Without wanting to invalidate anyone’s personal experience, could we try to be a bit more careful and speak only from our own experience?
There are people with eating disorders who need to take this medication, and reading such absolute statements can be really harmful, both mentally and physically.
Thank you and sorry!
just here to say i accidentally missed my dose yesterday and this shit royally fucked me up lol.
the most insane migraine all night, almost threw up. took half a dose at midnight with 4 advil and finally slept-ish. i feel hungover today.
anyway, don’t skip doses, friends.
I have been on Duloxetine 60mg for 12 days, prior I was on 40mg for one week, 30mg the week before and 20mg the week before that so almost 5 weeks in total. I was also weaning off Escitalopram in the first 3 weeks. I am incredibly low/depressed and really struggling and would really appreciate any success stories of people who have gone through similar and come out the other side 🙏 it is starting to impact my relationship too which is causing increased anxiety, I would love for it to start working soon.
I've been cymbalta for a little over a year, 30 mg twice a day. I'm having brain zaps all throughout the day even though I'm being very careful to take it every 12 hours. I take one dose with sugar-free cola (hoping that the fizz will make it dissolve faster) and one with water. I get shocked in my brain and fingers when I move my eyes to the side. It wakes me up sometimes, 2/10 experience.
Last year I got switched from Effexor because I was having constant withdrawals even when taking it twice a day. They did a genetic test and I do have slightly less CYPD26 function (one functional and one non-functional allele). I got moved to Cymbalta because it has a longer half-life and is processed by two enzymes.
For the past two months or so I've been having withdrawals again though. Am I doing something wrong? I don't want to quit, I vibe really well on SNRIs :(
I feel so sensitive I almost get panic attack and a small heat flush even thinking about quitting after reading the horror stories. I am only on 30mg for 9months, but I want to taper because it didn’t help resolve the main issue it was prescribed to me for. Now I am afraid to withdraw, any suggestions? Btw. first three weeks were terrible, I thought I am getting insane because of it.
Hi all - I’ve been on cymbalta a little over 3yrs after my first kid. I’ve never had issues like some describe. It’s really been a life saver. However, now I’m on zepbound and my anxiety has def shot up.
So I started poking around here… and it honestly just scares me.
I’m going to be on cymbalta or something for life. I need the help and my life is so much better on it.
Anyone else get scared about some posts that are like “worst mistake of my life”… this terrifies me to increase, but I know I need help.
Anyone on zepbound or other glp-1s and you anxiety go up? … did increasing dose help?
Kind words only please!
i've been on cymbalta for about a month now, and i really like it! i've tried a couple different medications & i had really bad reactions to all of them, and finally i'm feeling better. literally my only issue is that i've been running insanely hot. my roommate & i keep out apartment pretty cool usually, but lately i've been sweating all night & cannot sleep unless the AC is set on 60 or lower. also with it getting warmer outside, i'm noticing that i start sweating almost instantly when i'm outside & it tends to make me really annoyed & overstimulated. has anyone else dealt with this, or am i going crazy???