u/TwoDiscombobulated16

We only get one government funded IVF cycle (this is it). I’m 32F (husband 31M), AMH 0.5, AFC 10 (on monitoring cycle), FSH 8.5, 2 past pregnancies (unassisted life birth, unassisted ectopic pregnancy), doing IVF for mild MFI and tubal factor.

I was on Rapamycin 5mg weekly x 6 weeks with 2 week washout, Omnitrope 2.5mg daily and androgel 1 pump daily midluteal priming continued with stims.

I’m stimming with Rekovelle 12 mcg and Menopur 150 unit daily.

My CD2 baseline ultrasound showed only 5 follicles. I was hoping for closer to 10. If you had around 5 on your baseline, did more recruit with stims? How many did you retrieve?

I’m 32F with DOR, starting IVF due to secondary infertility (severe C section defect (to be repaired), one blocked tube, mild/moderate male factor).

My AMH is 0.5, FSH 8.5, and AFC 10. Confirmed no endometriosis via laparoscopy, and no hashimotos via labs, no hereditary history. My DOR is just shit luck.

Anyway, I’m starting rapamycin 5mg weekly x 8 weeks today prior to stims and retrieval. Anyone have a positive experience, or a very negative one alternatively? Any advise with dosing or TTC naturally while taking it (my RE said it was okay to continue, just stop meds if positive test)?

Thanks!

I’m 32F with AMH 0.5, FSH 8.6, and AFC 10. We conceived our daughter unassisted ~3.5yrs ago, and an ectopic in March, but due to series of truly shit events, are now being recommended IVF.

My husband’s counts are lowish (13mil, 1% morphology, below desired 24hr survival, otherwise normal), I have one blocked tube (ectopic surgically removed), abdominal scar tissue (emergency c section with post op infection, adhesions removed in March) and a large isthmocele (I think they said 1.5cm), and obviously DOR (no endometriosis confirmed via lap, and no hashimotos, just “shit luck” per RE).

They recommended IVF with ICSI and surgical repair of isthmocele prior to transfer.
I start Rapamune next week for 2 months as part of their DOR protocol (Dr.Victory in Windsor ON).

I guess i’m just a little overwhelmed, but also happy to have a plan (this marks 1 yr TTC #2). And they a very confident I’ll have success, and reasonably confident I’ll only need one retrieval. That said, DOR is not in my favour.

Anyone have similar stats and have success? Any experience with isthmocele repair prior to transfer? Should I push for anything else specifically? Should I get PGT testing? Anyone have issues with government funded IVF in Ontario? I have a lot of questions but idk if the answers will make a difference.

Thank you for reading this saga/rant and any advice or stories you can share!

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I had my saline ultrasound a few weeks ago after a left ectopic (surgically treated, tube retained at surgeon’s discretion intraoperatively) on March 27th, and it showed left tube possibly blocked (have to wait for RE to review imaging to confirm).

I know the working tube can pick up the egg from the other ovary in cases where the tube is removed, however since I still have both tubes does this not apply? I kinda wish the surgeon just took the tube if now every second month is just a write off/ectopic risk. He said both tubes looked good and no incisions had to be made to the ectopic side (it was right at the opening). Holding out some hope it’s actually open or still just has some inflammation from how recent it was.

Has anyone had an RE/doctor review this with them, or had success when they ovulated from the “blocked” side and working tube picked it up despite present blocked tube?