▲ 3 r/endocrinology+2 crossposts

21M – 250mg Test C once weekly, trough only 604 ng/dL. Looking for feedback on bloods

Hey everyone,
21 years old, currently running 250mg Testosterone Cypionate once per week.
Bloods were drawn at trough (2 hours before pinning, always mondays at 10 o'clock).

Main results:
• Total Testosterone: 604 ng/dL (6.04 ng/mL)
• SHBG: 10.6 nmol/L (low)
• Estradiol: 52 pg/mL (high)
• Free Testosterone (calculated; still awaiting results): ~210–220 pg/mL
• Lipids, liver, kidney: all good

Only side effect I’m noticing is pretty strong upper body acne (chest/shoulders/back). No water retention, mood issues, or libido problems.
I was surprised that my trough is only 604 ng/dL on 250mg/week. My natural friend is sitting at 719 ng/dL.
Thinking about splitting to 125mg twice weekly to stabilize levels and hopefully reduce the acne and E2 a bit.
Any thoughts on the trough level, the low SHBG, or the elevated E2/RBC? Would you adjust the dose/frequency or add anything?
Thanks.

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u/WhatADrip_ — 14 hours ago