u/beutguru

I just got my Ancestry test results back and some things really stood out to me:
• Slow COMT (AA)
• Slow MAOA (TT)
• MTHFR A1298C (one copy)
I've struggled with anxiety, depression, and OCD for as long as I can remember. About 5 years ago I started Zoloft, and it's been helpful and keeps me stable for the most part, but I still deal with so many symptoms daily.
Seeing these DNA results makes so much sense and honestly feels validating. I'm still waiting on my MyHeritage results so I can combine both Ancestry + MyHeritage for more complete data.
There's SO much information out there about these genes, methylation, supplements, etc. and I feel so lost trying to figure out what actually matters for me.
Has anyone else had similar results? Any advice on where to even start?

I had the worst panic attack the other day. It was triggered by one of my old OCD fears, and I went straight into full-blown panic mode. Since then, I’ve been on high alert and feeling anxious throughout the day.

I’m planning to talk to my doctor, but I’m really hoping this is just a temporary setback and not a sign that I need to switch medications. Zoloft was the first medication I ever tried, and it’s worked incredibly well for me for years. The thought of starting over with something new honestly scares me.

Has anyone else experienced a sudden spike in anxiety or a return of old OCD triggers after being stable on Zoloft long term?