u/iLoveSnooze

Hi everyone,

I’ve just done my first medicated cycle with Letrozole. I had two follicles and triggered Thursday night. I likely ovulated today around noon. Shortly after noon, I got the worst sciatic pain I’ve ever had. Has anyone ever experienced this when using Letrozole? Google says it can happen but it’s not common. Just looking for any similar experiences to make sure I’m not nuts! lol I know it’s sciatic pain because I have had a previous back injury but this time I don’t hurt my back or even do anything that would have. It’s so bizarre. I have also read this happens with endometriosis. I’ve not been diagnosed with endo and don’t have any symptoms of it. My cycles are pretty regular and I never have any ovulatory pain in a typical cycle.

Hi everyone,

I’ve just done my first medicated cycle with Letrozole. I had two follicles and triggered Thursday night. I likely ovulated today around noon. Shortly after noon, I got the worst sciatic pain I’ve ever had. Has anyone ever experienced this when using Letrozole? Google says it can happen but it’s not common. Just looking for any similar experiences to make sure I’m not nuts! lol

Ok don’t come for me. Haha! But- How annoying is it for a candidate to reach out to the HR person listed on the job announcement and ask if there is a tentative timeline for TJO’s?

A couple people in my office interviewed and are waiting to hear about a posting that had multiple spots open. We’re all wondering if it’s totally inappropriate for one of us to just reach out and inquire if TJOs have gone out or if they’re still in process. We do know this particular place was trying to hire before end of FY.

Any DROs in the group willing to give a short description of your day to day and what your production and quality standards are like? Extra interested to hear if you’ve gone from RQRS to DRO (or vice versa) and can offer a comparison of the two roles.

Thanks in advanced :)

After two early losses this year, my RE did

-karyotyping: normal for me and my husband

-APS :one value was one point high so we’re going to re test in 12 weeks and I’ll take baby aspirin as a precaution but she said she thinks the value is clinically insignificant.

-hysteroscopy: removed a small polyp

-endometrial biopsy: waiting for results

My TSH and other labs have all been normal. She also told me we can do progesterone if I want to (but my progesterone in my last pregnancy was good). She also said I can try Letrozole if the biopsy comes back normal.

I just am so anxious to try again and lose another one. I don’t know how to get past that. My last d&c was exactly a month ago and my body reset so fast. I’m already in cd7 of my first period/cycle since the d&c.

The polyp was small so I don’t think it was the main cause of the miscarriages but, who knows. The Anora test was inconclusive so we truly will never know.

This is such an emotional rollercoaster.

Hey everyone,

I had my follow up from my d&c today and my RE suggested some things because I’m not officially diagnosed with “recurrent pregnancy loss”. . (That diagnosis just hits me in a way that I can’t describe)

She is doing karyotyping, APS labs, and suggested a hysteroscopy to evaluate tubes and uterus better. She said she also will do a biopsy to test for endometritis.

I’ve had a normal SIS and an HSG that showed an open left tube and a sluggish but eventually open right tube. (I got pregnant after 6 months of negatives immediately after this hsg and confirmed right side ovulation).

I’m curious if anyone has had all of this testing done and had anything come back positive, what your journey has looked like?

We’re both healthy with essentially normal everything. My husband’s SA was amazing.

I’m really just looking for community to talk about this with. None of my friends have been anywhere near this situation.

Love to you all 🩷

I’m 4 days post d&c for my second miscarriage in 6 months. The two times I’ve gotten pregnant, I’ve miscarried. This time, we opted for a d&c with Anora testing.

I’ve been working with an RE since we started trying. (I’m 36 and the fertility clinic will see you after age 35 at any time here) All of my tests are good - labs, SIS, HSG, etc.. husband’s semen analysis was exceptional. My RE told me she was surprised this pregnancy ended in loss because everything looked very reassuring in the beginning.

Once we get the Anora back, she said she also wants to consider RPL labs and I’m hoping that will include karotyping and such.

No one but our close friends and parents know I’m going through this. I just want to scream. Post it on Facebook. Tell everyone, “hey, I’m drowning in sadness right now and no one can tell me why!”. I also wish that people were more open about miscarriage because it does help to see and hear stories similar to your own.

I just feel so lonely. I feel like my body is failing me. I know if the baby wasn’t healthy, my body did what nature intended it to do. But that doesn’t make me feel any better right now, honestly. I’m mad at my body. I’m mad at God. I’m just mad. Sad. Disappointed. This is awful. :(

I posted about an elective ultrasound showing I was only 5w5d when I should have been closer to 6w3d and caught some crap about getting an elective.
Well, turns out she was right.
I went to my clinic this past Tuesday (I should have been 6w6d) and the fetal pole only measured 5w3d without a heartbeat. While I know that’s early for a heartbeat, the pregnancy hadn’t grown at all.
So my clinic scheduled me a follow up scan for next Tuesday. I started spotting brown and now it’s progressed to cramping with light, dark red period-like flow.
I’m certain on my dates of Lmp and ovulation bc I’ve been working with a fertility clinic.
And of course it’s on a Friday so I’ll probably miscarry at home over the weekend. This is my second miscarriage in 6 months. All of my testing comes back normal. I’m so upset. We got pregnant the first try and it was a chemical. Then, 6 months later, we finally get pregnant again and now this.
I don’t understand how some people, that don’t even want kids, have multiple healthy pregnancies by mistake but, someone that genuinely wants to give a child a good life gets dealt this shitty hand.
I’m sorry, I’m just sad and angry.

Against my better judgement, I went for an elective ultrasound at what I thought would be 6w3d based on known LMP, known ovulation, and first positive 10dpo. So it leaves little room for dating error.
The tech measured my gestational sac in one measurement at 12.9mm and told me I was 5w1d. Yolk sac present but no fetal pole.
A 12.9mm gestational sac correlates with a 5w5d-6w1d gestation, which would make more sense.
I have a scan at my fertility clinic Wednesday but now I’m spiraling thinking I’m going to miscarry. Anyone have a similar story measurement/dating wise that came out okay? My betas were fine in the beginning. They didn’t test anymore after 19dpo.

Hey everyone,

I just wanted to share my positive HSG experience. When I was preparing for the test, I saw so many posts about how painful and awful it was for them. My experience wasn’t bad at all. However, I absolutely can see how and why it would be painful for others.

My RE did my test and she used lidocaine to numb my cervix. I haven’t seen that mentioned in many (if any) other posts about the test. I feel like that helped so much! Also, I did have some resistance and slow filling on my right side that required a little extra dye but, it ultimately cleared.

During the test, I didn’t feel any pain. I did take 800mg of advil about an hour before and I think that also helped.

The only discomfort I’m having the day after is some cramping and lower back pain on the right side. Which, since my tube likely had some debris in it (hence the slow fill and eventual spill compared to my left that was WIDE open), it makes sense.

I hope this does not come off as downplaying anyone else’s experience because I am certain this can be quite painful. I just wanted to give a positive experience for those that are super anxious beforehand like I was.
Love to all 🩷

I’m kind of stuck choosing the next step in our TTC journey.

Long story short, we got pregnant first try back in December but that ended in a chemical and we haven’t had success since.

All of my labs are normal. AMH is 1.98 (I’m 36). My husband’s SA was phenomenal. My saline ultrasound was clear. My 7dpo progesterone was 13.31 earlier this week.

So, I am ovulating on my own.

My RE suggests Letrozole.

She also said I could have an HSG if I wanted to.

At first, I wanted to just keep trying natural and put off the HSG bc I was able to get pregnant so I know at least one tube is working. But now, I’m reconsidering.

I’m wondering if I should do the HSG next cycle and have all the testing I could have possibly done over with, before turning to Letrozole in June maybe?

I’m so exhausted mentally and emotionally. I feel like I’m “normal” on paper but nothing is happening and I don’t know why. So maybe my only hope is Letrozole?

Idk. I’m just scared of the side effects of Letrozole if I’m being honest. I’m also a little scared of the HSG. The internet makes it sound awful.

Anyone have any friendly advice on what my next steps should be? Help me think this through rationally?