Welbutrin + Rexulti
Hi everyone,
I’m looking for personal experiences and thoughts about this combination.
Im F(36) was on SSRIs/SNRIs and CBT for around 10 years, and they didn’t help at all in fact it made the depressive episodes worse, gained a tremendous amount of weight on, and it caused hypothyroidism among other things.
I stopped antidepressants for about 5 years, then started Wellbutrin/bupropion about a year ago after a severe depressive episode that lasted 8 months.
I’m now on 300 mg SR, EMDR therapy, and it has helped with depression and CPTSD immensely.
And also, i take a small quarter dose of Seroquel/quetiapine for sleep
However, I still struggle with emotional flatness, anhedonia, freeze/shutdown mode, tiredness, and executive dysfunction. I can manage necessities, but I still feel stuck and not fully functional, especially with socializing, trying new things, going to the gym, and maintaining my health… etc.
I also was diagnosed with autism as an adult, which may be part of the freeze/executive dysfunction issue.
My psychiatrist prescribed Rexulti/brexpiprazole as an add-on to Wellbutrin, but I’m apprehensive. I’m scared it could undo the progress I’ve made or cause side effects like akathisia, emotional blunting, fatigue, or weight gain.
Has anyone added Rexulti to Wellbutrin for residual depression, anhedonia, freeze/shutdown, or executive dysfunction? Did it help or make things worse? What dose did you start on, and how long did it take to notice effects?