r/ureaplasmasupport

Hello, 34y male.

I was positive pcr test FVU one year ago on ureaplasma urealyticum. I took abx. I done 12 pcr test fvu (first morning void) after abx therapy at least pne test per month and every single is negative. I am curious is it possible that this bacteria survived therapy in my prostate and 12 months later to not colonize urethra again?

I read all the posts yeah yeah yeah. Okay but all my microbiome tests are normal my PFPT I’ve been in for 9 months says I’m improving but still tight.

I’ll feel normal for weeks and weeks and then I’ll have a day where I flare and have all of the same symptoms again. Redness burning itching urinary discomfort.

Still test negative. My last evvy looked perfect. Sex alcohol etc seem to trigger my symptoms.

I’m starting to get curious about MCAS? Has anyone had this infection trigger that response? I seem to feel worse the week before my period.

I treated in fall 2025 with 3 weeks doxy 3g azi and my husband did the same. We abstained for 8 weeks both test negative and then had sex. My symptoms didn’t get better with the abx. They only got better once I got rid of my iners but now I still have cyclic symptoms.

My husband and I just both test negative for everything again last week with me getting first morning PCR urine and swab and he got urethra swab and first morning urine. I just don’t see how it could still be Ureaplasma.

Do most of you have constant symptoms or symptoms that aren’t always there but come at times ?

has anyones spotting kept going after finishing treatment and testing negative? my pap is negative and no other confections. did it just really mess up my hormones or I just have a very sensitive cervix now? anyone used the estrogen cream down there

Please share how you got rid of PREVOTELLA Bivia

Luego de intentar con el esquema mino 14 días más azitromicina sigo igual.
Al 5 día más o menos de tomar azitromicina volvió el síntoma que más me ha perturbado que es el de ardor vaginal. Creí que podía deberse a la misma medicación termine todo me fui de vacaciones y continué teniendo mucho ardor escazes de flujo y sequedad en general.
Volví fui a un urólogo para ver si me recetaba kinesiología del suelo pélvico y me hiciera algún estudio me dijo que me recetaba lo del suelo pero que no podía hacer más que eso que tenía que volver a un ginecólogo.
Conseguí para hacerme un cultivo, me dió positivo otra vez U.U garnarella en baja cantidad, lactobacillus en baja cantidad y ph en 5
Tenía esperanza de que el ardor provenga de problemas hormonales porque he estado notando que en la fase de ovulación no suelto tener tanto ardor mientras que antes de la mentruqcion y post tengo mucho pero no fue así.
Estoy muy cansada hace desde marzo de 2024 que estoy así, no tengo fuerzas, no sé a dónde ir, la gente cree que es psicológico y me invalidan todo esto, acá en argentina hay mucha ignorancia sobre estos temas, no hablan de probióticos no se consiguen tengo que importarlos del exterior.
Tengo una depresión muy grande nunca pensé que se me iba a arruinar la vida así ya no se que más intentar no se a dónde ir. No necesito un milagros solo necesito saber qué tengo que hacer para poder salir de este pozo.
Mi madre fue al ginecólogo mismo que había ido yo y le comentó que seguía con el tema del ardor etc y le dijo que tenía una enfermedad venerea pueden creer??? Y le dijo que tenía que ir a un psiquiatra porque estaba muy afectada y mis padres lo defienden, me siento avergonzada, desesperanzada, cuando va a ser el día que consiga mis historia de éxito, como puede ser que no funcionen en mi los tratamientos? Malditos médicos hijos de p me dieron mal los esquemas, me dieron 7 días de doxi luego al tiempo 3 de azi luego doxi solo y así, millones de óvulos. Esta vez compré encimas digestivas de eeuu “serrapeptasa” tome NAC, use óvulos de ácido láctico y tome 14 días de minociclina los cuales me marearon muchísimo no podía caminar bien y después 4 días de azitromicina más probióticos y dmanose todos los días y no funcionó.
Realmente no tengo fuerzas, no sé si algún día voy a dejar esto atrás. Por qué no puedo salir de esto? 😭

My OB/GYN clinic literally sent my test results to someone else's phone number. This is highly sensitive personal information, and they didn't even bother to apologize. Like, do they know how to do anything right?
Anyway, the results came back negative again. I really thought a cervical swab would finally show something different this time, so I'm deeply disappointed and discouraged.
Because the results are negative, they just told me not to worry. But I am absolutely miserable. How am I supposed to stop worrying when they aren't even giving me any treatment?

Quel test est le plus fiable pour les hommes pour détecter ureaplasma parvum ? Le médecin lui propose un test urinaire mais j'ai peur que cela ne soit pas fiable .

Nous sommes dans une clinique de fertilité est-ce qu'il est possible de le détecter dans le spermogramme ?

Never enough success stories so wanted to come on here and share mine (& give some of you hope in doing so).

November 2025 I started having UTI symptoms, pretty shortly after having had sex for the first time with my bf. I should note that I never had any UTIs or yeast infections or anything of the sort prior to this, so some nerves were wracked, to say the least.

Main symptom was the standard burning while peeing, specifically toward the end. The first time around symptoms were pretty mild, initially I thought it was just dehydration, but when symptoms went on for a week or so, bf and I finally went to urgent care. Got some testing done, was told it was a standard UTI and prescribed Nitrofurantoin macrobid. Took that for 5 days or so, seemingly felt better.

Then the next month, around the same time (circa ovulation), symptoms came back, except significantly more aggressive. Woke up early, sweating, couldn’t lay down or sit still it was so uncomfortable, burning while peeing, pelvic discomfort. The evening prior, sex was painful as well. This time, bf and I decided instead of going to urgent care again we’d just order the Nitrofurantoin home to avoid the hassle. Took the meds, and again, seemingly felt fine for a bit. Azo urinary pain relief was also a serious life saver for peak symptoms.

Now again, because we were told it was just a standard UTI, we were taking wayy extra precaution w/ hygiene. Although again, I’ve never had any issues like this before, so I began to suspect it must be something else.

So when the aggressive symptoms came back a third time around in March (this time with hip pain??), I knew I had to take this into my own hands and do some proper research. Thanks to Reddit shadow medicine (God bless), I came across ureaplasma and ask my primary care dr to get tested. Result came back positive for ureaplasma urealyticum. Both my bf and I had it, but he was asymptomatic.

And before taking any antibiotics, I do a TON of research and ultimately decide to follow the European standard protocol, which seemed to be most effective from everything I’ve read. That’s 2 weeks doxycycline, 5 days azithromycin, for both partners.

My primary dr initially tried to prescribe me cipro (which I said no to as that’s a last resort antibiotic that can result in some serious side effects) and then tried to prescribe me 7 days of doxycycline, which I knew wouldn’t be enough on its own.

I then went to go see a urologist, who prescribed both my bf and I the exact course I requested (14 day doxy 5 day azithro) and that’s what we ended up taking, at the same time. The course did feel like forever, but thankfully neither of us had any crazy bad side effects, except for my bf having diarrhea the last few days on doxy. I did have some ongoing symptoms while I was taking the course, though. Oh, also we were not having sex during the course, and I was taking women’s health probiotics as a yeast infection preventative (long courses can do that).

We finished the course mid April, and since then, I’ve been doing great besides some occasional super mild lingering symptoms like discharge and it taking a second to pee sometimes. Besides the psychological damage, the extensive antibiotics having made my fungal bacne rebound (a month and a half or so of using nizoral dandruff shampoo w/ ketoconazole as a bodywash has made it mostly go away), and having broke up with said bf (for unrelated reasons lol), all is good now.

If there’s any advice I can give you, it’s to PLEASE ADVOCATE FOR YOURSELF. A lot of these doctors, especially primary care doctors / urgent care doctors, are not specialized enough to properly treat ureaplasma. Trust your instinct, and do what you have to do for your health.

From everything I’ve read, a single course of 7 day doxy is unlikely to eradicate the infection, and you’d rather avoid taking extra rounds of antibiotics if you don’t have to. I personally have 0 regrets having followed the european standard protocol, although I live in the US. And PLEASE treat your partner with the same course, even if they are asymptomatic.

Lastly, girls please just be safe with these guys. Before you, *these mfs* are God knows where doing God knows what with God knows who. And because a lot of guys are asymptomatic, they don’t even know they’re spreading ureaplasma everywhere. And it’s not well-known about enough! Makes me sickkkk to think about.

But yes anyways that’s my success story, hopefully at least one person feels better after reading this.

Hello,

I'm 21F who has been struggling with what seems to be ureaplasma or mycoplasma hominis for more than 3 months (end of March). I have been to the ER, 2 gynos, my GP, and now being sent to a dermatologist for my symptoms. I had countless tests done except these two because doctors refuse to test me saying it's not something that causes symptoms or make you sick (French guidelines).

I am struggling with bloating (my 1st symptom), urgency to pee (that turned into just bladder pain and bloat), itching on the vulva sometimes around the urethra more (after peeing), yellow discharge, lower back pain, abdominal pain (it's not only the reproductive area anymore but also up), my skin is really damaged down there, always red and burns sometimes.

The smell isn't bad but it's off.

All in all I have had periods when it felt better and worse but it's never been this bad.

Has anyone gotten treatment in France and where ?

After a string of tests, my primary care doctor/urologist finally traced my UTI symptoms to Ureaplasma. I’m currently on antibiotics to resolve it. Since I’m immunosuppressed (I’m on treatment for MS), this isn’t something I want to deal with on repeat, obviously.

My urologist recommended my girlfriend also get tested and treated, even though she isn’t showing any symptoms herself. His reasoning was that Ureaplasma can “ping pong” between partners, so treating just one of us without addressing potential reinfection risk doesn’t really solve the problem long-term.

She went to her gynecologist to get tested and start treatment, and they flat out refused. Their stance was that Ureaplasma is considered part of the normal vaginal microbiome, and that testing/treating someone without symptoms isn’t standard practice. She pushed back and explained the context (my diagnosis, immunosuppression, ping-pong risk) and they still declined.

From what I’ve read, this seems to be a genuinely contested area in the literature. Some sources do treat Ureaplasma as commensal/normal flora in asymptomatic people, especially certain species/subtypes, while others support partner treatment in cases like ours specifically because of reinfection risk. So I get that her gynecologist isn’t pulling this out of nowhere, but it feels like a disconnect between what my urologist is telling me and what her provider is telling her, and I’m the one who has to actually deal with the consequences if this comes back.

Has anyone dealt with something similar, either as the immunosuppressed partner or as someone whose doctor gave them the “it’s normal, we don’t treat it” answer? Curious whether her gynecologist’s position is common practice or if we should be pushing for a second opinion.

Hi everyone!

I was diagnosed with Ureaplasma Parvum at the beginning of May and was treated for it with 10 days of Doxy. Since then, I’ve had 4 negative pcr tests, waiting on the test results from one more pcr test. I’m still having pretty bad lingering symptoms (UTI like symptoms: burning, frequent urination, bladder pressure). I’ve seen a urologist and they did two urine PCR tests that tested for a ton of different bacteria’s, yeast, etc. All came back negative. I’ve done at least 5 urine cultures that come back negative. I was finally able to find a urogynocologist in my area that had a cancellation next week, so I was able to take that appointment and I’ll be meeting with her next Tuesday. This is my first time dealing with anything vaginal or urinary related. What are some things I should be bringing up to the urogynocologist? Any tests I should ask for? Medications? I would love advice on this. This has been exhausting both mentally and physically.

My husband and I recently completed a 14 day cycle of doxycycline and both tested negative for ureaplasma, however, about two weeks after testing negative (symptoms disappeared fully upon completing doxycycline), my symptoms returned, primarily extreme pelvic inflammation/discomfort. I never had any urinary symptoms with it, just pelvic inflammation. I believe undiagnosed ureaplasma contributed to multiple pregnancy losses in my past and were about to try to conceive again now that we both got negative tests, however, the lingering symptoms have me terrified that it’s not truly gone. Has anyone been reinfected despite both partners testing negative?

As I’m writing this, I’ve just got done crying for the umpteenth time today. I’m so frustrated and this infection is making me feel so depressed. I’m constantly on this app, reading research papers or asking ChatGPT about my symptoms. I have been dealing with this since March, (though I believe I was infected initially in January). I have been misdiagnosed with a yeast infection and BV several times until my doctor finally tested me for Ureaplasma in June which came back positive for ureaplasma parvum. She prescribed me doxycycline for 7 days. I had already started researching and knew I had it prior to the test results coming back. My doctor gas lit me telling me “discharge is normal” etc. I made sure to advocate for myself in order to get tested. On day 2 of taking doxycycline I just knew it wasn’t going to work. I called my PCP office again and requested another antibiotic (azithromycin) do take after doxycycline. (I’ve taken a microbio class and was familiar with how it can be resistant due to its biofilm). They told me to stick with my prescription and monitor symptoms and keep in touch if symptoms persist.

As expected doxy failed. They had me come in for another test 1 week later and tested me for the wrong culture. I then called back and they said they would use the same sample to test for myco/ureaplasma. ( 7 days later i have yet to get my results back). I was prescribed 7 days of moxifloxacin after crying on the phone to one of the nurses.

This has been my current routine for the past week and a half:

7 days: Kirkmans biofilm defense on an empty stomach
Uqora Defend urinary tract support (I plan on finishing the bottle which is a 1 month supply)

Day 8: moxifloxacin 10am (for the next 7 days)
Uqora defend urinary tract support 12:30pm
Kirkmans biofilm defense 5pm

I’m currently on day 3 of taking moxifloxacin and my symptoms have not improved, if not they’ve gotten a bit worse or that could be my anxiety. I’m considering calling my PCP tomorrow and requesting another 7 days of moxifloxacin. I can’t get an appointment with gynecology no earlier than mid August which is about 1.5 months from now.
I feel defeated at this point. Please if there is anyone who has any advice and what may have worked for them please let me know.

My current symptoms are urethral pressure/pain, warmth/slight biting while peeing, white/milky vaginal discharge (i feel discomfort/ itch when the discharge is passing), urethral inflammation.

Next week will be 4 weeks since I finished my second dose of antibiotics but I still have green discharge. I’m scared and annoyed that the antibiotics might of not worked. Does anyone still have green discharge after they finished antibiotics? I took a heavy dose of Fluconazole followed by azithromycin. at this point it’s like I’m waiting and counting the days until I can retest but if that didn’t work what will? Could it be ecoli?

So i have been diagnosed with ureaplasma parvum 3 years ago. I had back pain, vaginal itchiness as well as rectal, vaginal bruning, discharge smelling like vinegar and UTI symptoms such as frequent peeing, increased urgency, burning when peeing and even lingering stomach pain after peeing. I did two rounds of antibiotics and some if the symptoms got better. I still had the urinary symptoms and occassionally some itchiness. I got tested again a year ago (1.5 years after treatment and it was negative (urinary tract). I got tested again vaginally 6 months ago since the urinary symptoms were still there and I was entering a new relationship. Negative again. In january the urinary symptoms got worde again. I experienced some difficulty holding in pee and the burning got more intense. I went back to my gyno and she saw some paler areas near my urethra. So she suspected lichen. I have been using the creams as perscribed but it hasnt helped. Today I went to my gyno again and she said that it might not be LS afterall and she mentioned that maybe we retest for ureaplasma. This makes me very frustrated I thought this part was over. These tests are so expensive for it not to be accurate. I dont even know what I would tell my boyfriend, if there is still ureaplasma present. I got tested twice and it was negative otherwise I would not have started having sex without a condom. So yes I am very mad, I would not want to tell my boyfriend. I told him that I got tested before and I really dont want to tell him that I had ureaplasma previously.

I have had chronic BV for just shy of 2 years now. I’ve done countless courses of clindamycin and metro gel, oral metro, xaciato one time treatment, partner treatment, boric acid, probiotics, vaginal probiotics, etc. etc. etc. I then ended up testing positive for yeast and BV so treated both. I then saw my doctor again because I was still having symptoms and she did a wet mount and I was positive for yeast but no BV. We just treated the yeast with diflucan and I still have thick white discharge after sex and sometimes am itchy. No bad smell. In this whole span of time struggling with this I have done 3 separate tests for ureaplasma and mycoplasma that have all been negative. What are the chances I am still positive? I don’t even know where to go from here… I want to know if I can safely stop thinking I have ureaplasma/mycoplasma or if this still could very much be the case?

What did you do to stop the vaginal and uterine burning? The burning is everywhere.

I am at my wits end. I have had multiple rounds of antibiotics to no relief. I now have sharp pain mainly in right ovary. I had a transvag scan and it is clear except for a cyst on left. I am really depressed and dont know what to do. I have stabbing pain in my right ovary mostly. I feel my life is ruined. Doctors dont know what to do with me & now saying endometriosis perhaps. This started after my ex boyfriend travelled came back & we had sex. The MF obviouly cheated