r/ureaplasmasupport

Female if it matters.
Diagnosed with U. Parvum, I’m on day 11 out of 14 for doxy. I have 1g of azithro to take 12 hrs after my last doxy dose.

My bladder pain/discomfort has subsided a bit, but still very much there, however my urethra is SO inflamed. I am in constant pain. My PCP looked at it today and said it was swollen and red. Slight vaginal symptoms but they came on a week after doxy use, so probably a yeast infection. 🙄

I know no one here can have answers. I’m just kind of venting I guess. I’ve been reading that symptoms can linger but it also could mean I need further treatment. I don’t really want to have to take an extra week of antibiotics. My stomach is already so messed up.

My urogyno said that if the doxycycline doesn’t work then she’s going to investigate non-infectious causes. But surely it’s the U. Parvum that’s causing these issues…

I’ve tested negative for UTI, STDs etc multiple times.

It’s severely affecting my dating and sex life. I am so fucking depressed.
This sucks.

I've now treated this bacterial infection twice in my lifetime.

And it was relatively simple to treat the first time. Just a 7-day course of doxycycline.

I was recently diagnosed with a different strain. I'm sexually active and it was with a different partner.

However, the doctor I saw this time advised not to treat it. He said if it's asymptomatic, I shouldn't bother.

I did not follow his advice, and have decided to treat it again. Because the nonchalant way he delivered that advice didn't sit right with me.

Why would I continue going out into the world passing ureaplasma around, even if I'm not seeing any symptoms? I should tackle it while I have it so future partners aren't exposed.

Just a weird little story. Some docs really don't consider it an STI or really care about treating it that much in males.

6 weeks ago I posted about some unexplained irritation I was experiencing on and off since October 2025. There were so many potential causes as so much happened in such a short period of time... I had no long treated Ureaplasma, then developed and treated what I believe was CV and also stopped my contraceptive pill. Using Kirkland toilet paper 6 months later is what made the irritation more severe, frequent and noticeable.

7 weeks ago I had my last appointment where i was given a specialist referral for my irritation as their avenues of treating me had failed. From April to June they first suspected it to be a yeast infection and took a swab test before giving me fluconazole, but tests came back negative so treatment obviously did not help. They also suspected my issue could be lichen sclerosus or lichen planus. I was sent home with a steroid cream which made everything for me so much worse. On this last appointment I had at the end of June, after being told that i will be on a long waiting list for the specialist I decided to make a suggestion to my doctor to try estrogen cream. I had nothing else to lose at that point and luckily she agreed. I was prescribed Ovestin cream to use nightly for 2 weeks, then every other night for 2 weeks. Its been 3 weeks since I last used the cream and I haven't felt even a twinge of irritation since! Honestly I am so happy that the ovestin worked as my specialist appointment has been booked in a year's time! 😮‍💨

My one year anniversary of when I finished taking treatment for Ureaplasma is in two weeks. What a journey it has been, I am still coming up as negative on tests and have not felt any symptoms I felt during Ureaplasma since this time last year.

Despite everything, I am thankful. Ureaplasma helped me see my ex's true nature which saved me from being in a disappointing, sided relationship.

Im also thankful for the support this sub has given to me over the past year, it truly means a lot. This is definitely my last update post for this sub as I feel there's nothing else I can contribute now... I will still linger and comment on other's posts from time to time. Just to share knowledge and experience.

hi, im 20 and ive been struggling with what i thought was just chronic yeast infections for a handful of years now.

Back in January, i had gotten diagnosed with chronic yeast infections and was given 6+ months of doses for fluconazole.

earlier this summer, i was having pretty severe abdominal cramps and got my period (getting my period was very unusual since with my IUD and being on spironolactone, i had not previously had one since early 2025). I was very concerned and went to the OBGYN assuming my IUD may have been knocked out of place. Nope. Tested me positive for ureaplasma urealyticum.

I finished the 10 days of doxycycline a little over a month ago and have still had lingering symptoms. I really don’t know what to do to treat this more.

I was also seeing people talk about how this is connected to IBS or something potentially? I’ve had IBS for 5+ years so now I’m starting to feel like ureaplasma might have been the underlying issue in every gyno/gastro issue I’ve experienced.

I’m very sorry for the long post, I’m hoping others may have advice or suggestions pertaining to more testing or treatment plans to bring up to my provider.

So for the year of 2025 I dealt with chronic yeast infections my OB/GYN can never figure out the problem so I always just got treated for yeast infections and sometimes BV I was starting to have them no less than seven times a year so I’m like something has to be wrong. I went to another OB/GYN in like 2026 January because my original one closed down. They diagnosed me with mycoplasma genitilium and ureaplasma parvum I was actually happy because I’m like I can treat this and finally stop my chronic cycle of yeast infections . I did treat it and I felt better 100% with Doxi and moxi I didnt know it was a 2week treatment so i took at the same time both in 1 week span all was well about literally a month later march i got reexposed with a old partner my symptoms is always just super uncomfortable no urinary problems no bladder problems just itching unlike maybe I got re-exposed from this partner because when I thought about it, we did something in the year of 2025 but way in the beginning I still honestly don’t know how I could’ve missed that but anyway treated it again and never been the same since I tried all types of supplements probiotics, probiotics, breaking biofilm changing my diet, drinking clove, tea, ginger, garlic, all that still nothing and it’s months later now about to go into September kind of just praying that it just goes away, but a part of me wants to know if anyone has dealt with persistent symptoms after treating and how you got rid of them I keep testing negative for everything but a part of me feels like it’s still inside of me. Maybe it came resistant or something it won’t show up. I’m not sure but I cannot live like this forever. I really need help but all the OB/GYN’s basically dismissed me. I don’t know anymore

i need this to end so bad idek know how long i had it b4 getting first tested in may. it makes me upset and scares me that’ll b infertile when my time comes to have children

Bonjour,

Est ce que chez certains hommes, vous avez en symptômes un precum visqueux à l’extrême au point de pouvoir faire des filaments d’une trentaine de centimètres sans problème ni cassure si vous le touchez entre le méat et le doigt ?

Je me demande si c’est l’ureaplasma qui créé ce problème….

D’autres ont ils ce soucis svp ?

Ive been dealing w pelvic pain and urethritis for 7 years. Took random abx such as cipro doxy+azi twice. Probably the first time I teinfected myself or I wouldn't know anyway as I had sex w wife soon after. I went to urologist and wqs tested negative for everything via microgendx in the beginning however my wife just tested positive for UP. I did 10 days doxy+azi. 24hrs after the doxy my symptoms came back. I cant take moxy due the qt interval as I have an arrythmia. What should I do now? I feel like im screwed for life at this point

Quiero volver a mi vida normal

Disfrutar como antes

Fui con un urólogo y me diagnóstico epidimitis crónica con uretritis

Me recetó 20 pastillas de ciprofloxacino con doxiciclina,

Me da miedo los efectos secundarios pero no veo más opción

La primera pastilla me dió efectos secundarios tipo hormigueo y dolor en extremidades

Pero si no tomo el cipro, entonces que me podrá curar?

Hey guys, so I need some advice or at least maybe someone who’s been in the same boat as me.

So for the past 9 months I’ve been experiencing vaginal and rectum itching and burning. It’s been almost everyday. At the beginning it felt like it was constantly happening all day. Now I can feel it’s happening everyday but not constantly throughout the day if that makes sense. Some days my vagina itches more than it
Burns or other days my butt burns more than my vagina itches or burns. And when I say my butt I’m mostly talking in between my cracks. My other symptoms include itching that feels like it’s mostly on my hands and feet that happen from time to time and sometimes my lips itches. My left thigh/butt will occasionally ache but it’s more like a deep ache.

I’ve been to my pcp and gynecologist multiple times. I’ve had a Pap smear and has been tested for the most common stds and the others that’s included on the big panel such as mycoplasma, Ureaplasma, strep B, and more it’s just a lot to name. I’ve been prescribed estrogen cream, topical steroid ointment and nothing seemed to change.

So if anyone has some advice please let me know I’m desperate and would like to get to the root of my cause.

Hi guys,

I have been diagnosed with ureaplasma about 2 years ago after sleeping with some chick (only after that I found out that she smelled funny when she was sleeping). I was prescribed doxy and felt great for a couple of weeks. Of course infection would come back but somehow I tested negative although symptoms were persistent.

Last night I had pelvic pain, urgency and irritation but after taking 250 mg of azithromycin I felt MUCH better and immediately fell asleep and slept like a baby. I don't know if it's linked but now I have problems with my right knee and foot, I think I have inflammation.

I cannot take doxy since the last time I took it I had intracranial hypertension (thinking I might have developed it after taking 2-3 courses of doxy).

Are there any alternatives to doxy? Cause, if I understand correctly the treatment course is 2 weeks doxy + azythromicin.. I will take azythromicin for sure but is there any alternative to doxy? I still can't understand which one of these kills the bacteria and which one just stops it from reproducing.

My life has been hell for the past year so I hope I will beat it.

Thank you all!

Hi all,

I am currently being treated for pid(they found ureaplasma) and on antibiotics. Had my periods on 30th July and my pap was done on 13th Aug(around ovulation).
I bled heavily on first day and decreased after that but today I see some more blood.
Anyone had a similar experience? My pap results haven’t come back yet but I am panicking. This was my first pap.

I’m honestly at my wits’ end and wondering if anyone has dealt with something similar.

I keep having urinary/urethral symptoms and Enterococcus faecalis has shown up on my urine cultures more than once. My most recent clean-catch culture grew 10,000–49,999 CFU/mL of Enterococcus faecalis. I had already had a positive strep b test in July which lead to me getting tested for ureaplasma and treated with doxycycline.

What makes me even more confused is that a few weeks ago a week AFTER being treated for the strep b, I had a catheterized urine sample that showed no growth at all. So if my bladder was clear then, where is the Enterococcus coming from now? Is this linked to ureaplasma? I was treated with a 7 day doxycycline treatment and symptoms went away and then came back. They have FINALLY agreed to give me another week of doxycycline while I wait for my results , but I haven’t even done anything sexual in the past few days so I have no idea where the uti came from. This is so frustrating. I’m just trying to figure out if it could be related to ureaplasma and if it’s even worth treating ureaplasma anymore ? I just feel like I’m gonna be stuck like this. I just to get all these infections from sexual activity but I stopped in March and only stuck to masturbation maybe once a week. I started getting infections (uti,bv,yeast)out of nowhere in July and they haven’t stopped even with ureaplasma treatment with doxycycline . It’s just not making sense. Any advice would really help . I’ve been trying vaginal probiotics and boric acid but I’m not sure they are doing my ch.

Hi everyone! I thought I would come on here and share a bit of positivity. This is a bit of a long story but hopefully it brings some hope.

About three years ago I started getting persistent BV/yeast infection-like symptoms and ovarian pain/tingles. Everything kept coming out negative so I would just use some boric acid and pray. It would come and go and doctors wrote it off as “hormones”. I was put on multiple rounds of different birth controls but nothing helped and I got used to the irritation.

Last year I began to experience the worst vaginal itching and irritation of my life. Then I began to have UTI after UTI. No antibiotics worked and they would cause me to have back and forth rounds of BV and yeast infections. Finally after 9 months of that, a new doctor (this was my fourth one) swabbed me for ureaplasma/mycoplasma and took a vaginal biopsy. A week later I found out I had lichenoid dermatitis and ureaplasma parvum! I was put on one week of doxycycline 100 mg BID and I was given Clobetasol ointment for the Dermatitis. 6 weeks go by and I knew I still had ureaplasma. I had a vaginal ultrasound and it came back normal but I did a UA and a swab again and I still had it. This time my partner was treated and I was treated for two weeks doxycycline 100mg BID. I was not given the option of azithromycin but I am allergic so I let it go.

After that round of antibiotics, I still felt off so I ordered my own Evvy test and turns out I had BV. Took metronidazole, took a preemptive fluconazole for any yeast infections and finally…. Relief. I still had residual irritation from the dermatitis but I have gotten it down to hydrocortisone cream once a week at night and I don’t think I’m gonna be needing it anymore!

I will say that throughout this, many doctors dismissed me. I was given multiple antihistamines saying it was an allergy. I had one doctor say I had interstitial cystitis. No one could given me an answer until 3 years of torture. I still am not 100 percent but my ureaplasma symptoms are entirely gone. I am also happy to say I have tested negative :). I did take probiotics throughout but now only take them three times a week as a maintenance dose.

Please feel free to ask me any questions. My presentation was a little “weird” for ureaplasma but I am just happy to be on the other side.

Hi all,

So 3 months ago i was exposed to ureaplasma, i had a post here under my old throwaway acc "soggy application" if anyone remembers them.

I tested negative after the partner tested positive, at first we assumed i was just healing but its been two weeks and i am now having minor/clear disharge leak in the morning again in penis tip + it is still enflamed and sensitive to friction, overall looks infected. I had azithromicin 1g back when all of this started and a 2 week course of doxy around 5 weeks later which helped the most and got rid of my urine urgency/frequency and pain but still have these redisual stubborn symptoms.

Today after having a menty b to my doctor about it all, I was prescribed 2 weeks of doxy followed by 4 days of azith with two tablets taken on the first day of azith, and yes, i referred my doctor to this sub and the linked studies which made her want to give it a go. She also prescribed a mild hydrocortisone for the glans/meatus so hopes are high.

Now ive read about biofilms and just wanted to know what else i can do help get rid of this? Should i take biofilm disruptors during or delay treatment for a couple days first?

Did the dual treatment sort you out? If so, let me know.

If this doesnt work, ill be truly up shit creek as the one thing she will not prescribe is moxi or a flox med and to be honest they kinda scare me anyway.

So i had yeast infection two months back ,treated myself using otc drugs ..got better then got my periods and the symptoms came back again just that this time there was no classic yeast discharge just…
While still battling that i got uti
Doc gave antibiotics for that got better but after some days the vaginal issues came back

I went to the gynae and was prescribed clotrimazole clindamycin and tinidazole suppositories
Symptoms were getting relieved during use but by the end of treatment started getting vaginal discomfort again

And followed by uti symptoms
And right now battling vulvar burning with no itching or discharge

Feels like i have hot sauce on my vulva and the symptoms appear later into the day like i mean during the evening and night time and mostly while im seated
No pain on touch and no discharge and im about to get my periods soon

Guys i do want to get tested for ureaplasma but where im from there’s no tests for that
And im all alone in this
No financial help what so ever

Is this how im gonna suffer forever??????

I’ve been dealing with symptoms from the infection for awhile!
I tested positive on December 31st 2025 and went through 2 different rounds of antibiotics. Apparently it cleared with the 2nd which was 21 days of doxy and 5 days of an 5 days of azithromycin. I did 2 tests after 6 weeks of treatment, 1 with Evvy, 1 a month later with wisp. Both negative for all forms of urea. My Evvy test said:
(From my chat gpt when I uploaded screenshots)
Protective score: 96% — very high.
Disruptive microbes: very low.
Diversity score: 0.2 (low) — but in this context, that’s not a bad finding. With such a high protective score, low diversity generally means a small number of protective Lactobacillus species are dominating rather than lots of competing organisms.
Community State Type: Type 1-A, which Evvy describes as predominantly protective bacteria and the type most strongly associated with protection against vaginal infections.

All of this but I still had ongoing discharge 3-4x a day. I have this white, lotion like discharge that dries up hard and sometimes a little clumpy. It doesn’t have a fish smell but it’s a sour smell and I hate it so much!

I am going to a new gyno this Friday for an annual but the previous gynecologists have absolutely failed me and I’m exhausted. Sex is still good but it doesn’t feel the same maybe because I’m self conscious?

This is the only symptom that hasn’t cleared and it’s taking a toll on me.
I look through all of the subs and no one specifically talks about discharge being their lingering symptom and what they did to get rid of it.

Has anyone tested at 3 weeks post treatment and got positive but at 8 weeks negative?

First treatment was doxy and azithromycin- 4 tests were positive 3 weeks after finishing meds.

Restarted meds.

10 days on doxy first then 4 days into minocycline and tested on the 4th day of mino and I was negative.
My doctor said the meds shouldn’t have an affect and that if I’m negative then it’s accurate cause the tests are so sensitive.

Is it possible it’s a false negative?