u/Carriage2York

>Following an application from Alzchem Trostberg GmbH, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Austria, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to creatine and improvement in cognitive function. The Panel considers that the food constituent, creatine, is sufficiently characterised. An improvement in cognitive function in one or more of its domains is a beneficial physiological effect. The applicant identified 21 human intervention studies on creatine supplementation and measures of cognitive function through a literature search. Two additional studies published after the search was conducted were identified through the reference list of a meta-analysis. In weighing the evidence, the Panel took into account that the acute effect of creatine on working memory, observed in two studies at 20 g/day for 5–7 days, was not seen at lower doses (2.2–14 g/day), or with continuous consumption (5 g/day for 6 weeks following a 5-day loading phase). Furthermore, the effect on response inhibition at 20 g/day for 7 days was an isolated finding among 10 intervention studies in healthy individuals, with no effects observed on other cognitive domains. The Panel also considered that the three intervention studies conducted in diseased individuals do not support an effect of creatine supplementation on cognition, and that the available evidence for a mechanism by which creatine could exert the claimed effect is weak. The Panel concludes that a cause-and-effect relationship has not been established between creatine supplementation and an improvement in cognitive function in one or more of its domains.

https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2024.9100

In stressful situations, especially when dealing with people, my heart rate rises above 100/minute. My normal resting heart rate is around 60/minute. I tried taking the beta-blocker Bisoprolol at a low dose of 2.5 mg, but it caused my resting heart rate to drop too low, below 50/minute, and I felt weak.

Do you have any suggestions or personal experiences?

In stressful situations, especially when dealing with people, my heart rate rises above 100/minute. My normal resting heart rate is around 60/minute. I tried taking the beta-blocker Bisoprolol at a low dose of 2.5 mg, but it caused my resting heart rate to drop too low, below 50/minute, and I felt weak.

Do you have any suggestions or personal experiences?

In stressful situations, especially when dealing with people, my heart rate rises above 100/minute. My normal resting heart rate is around 60/minute. I tried taking the beta-blocker Bisoprolol at a low dose of 2.5 mg, but it caused my resting heart rate to drop too low, below 50/minute, and I felt weak.

Do you have any suggestions or personal experiences?

My mouth is open while sleeping and my saliva is dripping out of my mouth. I often wake up with a wet mouth and a wet pillow. It's very uncomfortable. Plus, my mouth feels awful when I wake up.

Do you have any hacks to keep your mouth closed while sleeping? I've been thinking about taping my mouth shut to keep it closed, but I'm worried about suffocation or lack of oxygen.

Edit: It happens to me when I sleep on my side too. Not just on my back.

Which ones? And have your own experiences confirmed the findings of that study?

Do you actually decide what to take based on the findings of scientific studies, or on something else?

Is it 3.5 Flash? But it's extremely fast compared to AI studio. What is the thinking level?

Neočkovaný předškolák z Ostravska zemřel po onemocnění záškrtem