u/Confident_Craft459

If so, do you notice any improvement in brain fog? Or anything else? Heard about it on a podcast and thinking of trying it.

Tirzepatide has basically eliminated my IBS symptoms and I've loved being able to eat all foods again!

However I recently started peptides, wolverine blend (BPC157/TB500) and DISP and noticed my stomach issues returning after eating certain foods. Anyone else experience this?

The only other change is that I increased my progesterone from 100 to 200.

Other than that I've been on estradiol, progesterone, testosterone, vaginal estradiol, tirzepatide for almost three years.

I know progesterone cream doesn't absorb well systemically but I'm wondering if anyone uses it in addition to their oral progesterone and if so, if it gives them a little more help with sleep.

Thinking of trying this. I already take 100mg oral progesterone and 100mg vaginal progesterone. I sleep ok but still could use some help in that area.

I thought I would share my most recent dose change and how it impacted my mood and marriage in hopes it will help someone else who is currently in the middle of adjusting to their HRT.

For background, I'm 52, married 25 years, two years post meno, and two years on HRT. I started on .0375 patch, then went to .05, then .075, then .1, then back down to .075 most recently due to the .1 causing severe insomnia and other meno symptoms returning.

I changed from .1 to .075 2.5 months ago. And I remember telling my husband that I was changing my patch dose and fyi it may have some impacts while I adjust. Well, I had no idea just how much it would impact my moods. over the past 2.5 months I've had terrible anxiety, sadness, anhedonia. Also had rage towards my husband. I blamed it on life changes, including my daughter graduating college and moving out. It was an extremely stressful and emotional time for me as I coordinated all family events surrounding the graduation and dealing with the fact that my life was changing due to my kids moving out. My brain was so messed up I couldn't even think that it was due to my patch dose change, and of course my husband didn't even remember I said that to him. And honestly if he had remembered and he said something to me, it would not have gone well for him.

I was sooo mean to him over the past 2.5 months. The very sight of him pissed me off and I actually thought I wanted a divorce and I didn't love him anymore. It was basically the same feeling I used to get when I was pms-ing except that only lasted a few days, not 2.5 months! We didn't have sex for that time either because, well I hated him.

Then one morning, about two weeks ago, I woke up feeling like a cloud had completely lifted. I felt amazingly clear headed. I felt lovingly towards my husband again. He didn't annoy me anymore (well not more than usual lol) and I wanted to have sex again. I'm not sad anymore and my anxiety level has gone down tremendously. I also feel like going out and doing things again.

It was so weird how it switched just like that from one day to the next.

When I used to have cycles, I would always know when I was ovulating because I would get ovulation pains on one or the other side (I guess whatever ovary was releasing the egg??).

Anyway, I am now almost three years post meno, and been on HRT since I was post meno. And since starting I get these same types of pains once in a while. Are my ovaries waking up from the HRT? The pain isn't super painful and doesn't bother me. I just find it a little strange. Anyone else have or had this sensation when they were still having cycles? And did it come back on HRT post meno?

I took my first dose and had a weird reaction. Wondering if this is normal and if I should try again or stop. I also have a message into the doctor but haven't heard back. I got dizzy, which subsided after some time but then that night I had really bad insomnia. Anyone else?

Did it cause the initial dread shed? If so, how long did it last?

Did it cause you to get an increase in body/facial hair?

Any other side effects?

How long did it take to see results?

Do you recommend it?

Tried the topical but it made my head super itchy and then found out it's toxic to pets so didn't want to risk it with my dog.

Has anyone increased their use of vaginal estradiol (maybe more than twice a week) and notice a difference in libido?

I'm already on testosterone cream but I've noticed on days I do vaginal estradiol cream, I have an increase in lubrication and therefore feel more like having sex. Should I increase to daily? I have an appt with my doctor tomorrow to discuss but wanted to get anecdotal evidence if possible.

I've been taking sermorelin for a month now. I had to switch to the morning because I was having a hard time taking it at night on an empty stomach. I was fine waiting until three hours after I ate, but the problem is that I can't sleep on a completely empty stomach.

Anyone else in this situation that has figured out a solution? I was hoping this would help with sleep but it hasn't and I think the reason is because I'm not taking it at night. I have lost an inch on my waist so that's a definite plus!

I can't fall asleep or stay asleep because my heart pounds in my ears. Does this happen to anyone else and if so, how do you stop it?

I'm on .075 estradiol and 100 progesterone. I already tried increasing estradiol to .1 for six months but sleep got worse. I've tried going to 200 progesterone and although it helped with sleep, it made me way too irritable all the time and it killed any hope of an orgasm.

I also take l-theanine, magnesium. Tried cortisol support supplement, Lavela, gummies with other supplements, and although these help with sleep I still have that pounding that wakes me up and then have a hard time falling back asleep.

I've seen a cardiologist and have had a full work up and my heart is fine.

What else can I try? It's sooo annoying and I really need to sleep!

What does everyone use? Anyone swear by any particular brand or type? Getting desperate and would like to add a good magnesium glycinate supplement to my nightly routine. I need to sleep consistently!!!