how do you resolve this exercice ?

how do you resolve this exercice ?

  1. The pedigree below shows the family tree of a family affected by a recessive monogenic disorder that is not sex-linked. If the frequency of heterozygotes in the population in question is negligible, what is the probability that the child in the last generation will have the disorder?

1: 1/16

2: 1/8

3: 1/4

4: 1/2

thanks a lot

u/Sure-Roof-7681 — 6 days ago

Is it well placed ?

The Shimano cleats seem to be installed correctly (all the screws are centered), but there's a small piece sticking out on the inside of the shoe.

Is this normal? Thank you very much.

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u/Sure-Roof-7681 — 2 months ago

11-32 with dura ace 9100 doesn’t seems to work with me ? Why ?

Hello,

I have a Dura-Ace 9100 derailleur and I’d like to install an 11-32 cassette with a 52-36 chainring up front on my 2017 Canyon Ultimate SLX with rim brakes.

I know the maximum is 30T, but I’ve seen a lot of people say it works fine. So I tried it, but I couldn’t get onto the large chainring with the 52 in the front . I’ve tried every possible adjustment…

Do you have any tips? Does this not work on all bikes?

Thank you very much

reddit.com
u/Sure-Roof-7681 — 2 months ago

11-32 with dura ace 9100 doesn’t seems to work with me.

Hello,

I have a Dura-Ace 9100 derailleur and I’d like to install an 11-32 cassette with a 52-36 chainring up front on my 2017 Canyon Ultimate SLX with rim brakes.

I know the maximum is 30T, but I’ve seen a lot of people say it works fine. So I tried it, but I couldn’t get onto the large chainring with the 52 t in the front I’ve tried every possible adjustment…

Do you have any tips? Does this not work on all bikes?

Thank you very much

reddit.com
u/Sure-Roof-7681 — 2 months ago

Raid 0 + Mac OS sonoma on raid disc on imac 2011 possible ?

Hello, I would like to give my 2011 iMac a new life. I want to upgrade to macOS Sonoma using OCLP, but I would like to install the macOS system on a RAID 0 array. Is this possible?

I have already looked online and the answer I found was that it is unfortunately not possible because, when switching to the APFS format, Apple blocks this—even with Carbon Copy Cloner, which used to allow it on operating systems prior to Big Sur.

I would love to get your expertise on this!

Thank you very much for your feedback.

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u/Sure-Roof-7681 — 2 months ago

Carbon frame damages how bad is it ?🫪

Like many people here, the chain dropped and damaged my Carbon bike frame.
It’s a 2018 Canyon Ultimate SLX.

As you can see in my photo, there are several marks.
From what I can see:

The paint has cracked (there is a slightly longer crack on top is it something to worry about…), in other places the more superficial layer of carbon has been slightly damaged, and at the largest impact point, it looks like the second layer of carbon is visible over an area of about 3mm x 1mm.

The damage isn't exactly on the bottom bracket shell but slightly behind it, which is what worries me because a lot of force is exerted on that specific area.

I know carbon frames are fragile, but to what extent?

Thank you for your answers.

u/Sure-Roof-7681 — 2 months ago

Carbon frame damages how bad is it ?🫪

Like many people here, the chain dropped and damaged my Carbon bike frame.
It’s a 2018 Canyon Ultimate SLX.

As you can see in my photo, there are several marks.
From what I can see:

The paint has cracked (there is a slightly longer crack on top is it something to worry about…), in other places the more superficial layer of carbon has been slightly damaged, and at the largest impact point, it looks like the second layer of carbon is visible over an area of about 3mm x 1mm.

The damage isn't exactly on the bottom bracket shell but slightly behind it, which is what worries me because a lot of force is exerted on that specific area.

I know carbon frames are fragile, but to what extent?

Thank you for your answers.

u/Sure-Roof-7681 — 2 months ago

Best mavic wheels ?

Hello, which are the better wheels between the

Mavic Cosmic Pro Carbon
Mavic Cosmic SL45

Both are rim brakes

Please feel free to share your thoughts—I’m having a hard time really understanding the differences

Thank you so much!!

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u/Sure-Roof-7681 — 2 months ago
▲ 2 r/mac

Raid 0 imac 2011 how does this works

I don't really understand what RAID 0 is for, because you can't combine the drive that holds our macOS system with another drive. So how does that make the computer faster? Isn't it possible to do that after all?

Thank you so much for your explanation!!

reddit.com
u/Sure-Roof-7681 — 3 months ago

Canyon ultimate cf slx 8.0 2018 rims breaks for 800-1000€ good deal ?

Clean bike with sl cosmic Carbon wheels 40mm.
Équiped with di2 ultegra
I may be able to negociate to 800€
Is it a good deal ?

Many thanks !!

reddit.com
u/Sure-Roof-7681 — 3 months ago

What size canyon ultimate cf slx 8.0 for 6.5´high

What bike size would you recommend? I was initially interested in a Specialized Tarmac SL4, and their largest size (61) corresponds to size XL at Canyon! (If I'm not mistaken). People taller than me have told me they had no problems with the Specialized 61.

Which size should I choose from Canyon—XL or 2XL?

Thanks so much!!

reddit.com
u/Sure-Roof-7681 — 3 months ago

What about riding with standard 28 mm-wide tires on gravel roads with a sl4 tarmac ? I’ve seen that it’s possible to switch to 30 mm tires, even though that significantly reduces the clearance between the frame and the tire. Have you ever tried this yourself? Is it comfortable—or even just possible—to ride on gravel roads with 28 mm tires?

Many thanks !!

reddit.com
u/Sure-Roof-7681 — 4 months ago