u/ZealousidealSlip987

i feel like i need to ask for help maybe me n my partner been doing ketamine together and have been getting in k holes for almost 5 days straight this was after a big fight as well my mental health has already been unstable when we met i was having a hard time as you know and that thing happened at hanalei and he had a history of being in jail due to psychosis on mushrooms and bashing a cops head in and breaking their scull im having a hard time wrapping my head around this and im scared for my life and situation sometimes because of my history being around mentally unwell and my partner had been taking a lot more k than me throughout these days like during the day and stuff and is acting increasinly more manic its been so scary cuz i havent been in contact w friends or a therapist or really anyone and had some amazing the most amazing psychedlic and healing experiences w him but also he is barely sleeping and cleaning the whole house super ocd and earlier when i tried to make coffee he was holding me hand and wouldnt let go till he cleaned the whole sink and then was like no dont worry its ok and like wouldnt let me out of his grasp for a second till i got scared and thats what would happen a few times on the k hed say something or an attitude would shift which would trigger a huge panic attack for me he talks about getting nano tech off the body and like its just been a lot i dont know what to do in this situation

Sorry i used ai to help me write some more of my questions as I’m honestly just a little scared trying to wrap my head around this all right now

**Has anyone experienced ketamine + severe sleep deprivation causing mania or psychosis? I’m scared and trying to understand what’s happening.**

I’m posting because I feel isolated right now and could really use insight from people who have experience with ketamine, K-holes, mania, or drug-induced psychosis. I am also looking into professional help I know Reddit can’t diagnose this situation.

My partner and I have been doing ketamine together for almost five days, including repeatedly going into K-holes. This started after we had a really intense fight. My mental health was already not in the best place before this, and I realize continuing to use ketamine in that state was probably not a good idea.
My partner has been taking significantly more ketamine than me, including throughout the daytime, and has barely been sleeping. Over the last few days his behavior has become increasingly intense and what looks to me like manic or obsessive behavior. He has been cleaning the house almost nonstop and getting extremely fixated on things being a certain way.

He has also been talking about things like getting “nanotechnology” off of the body, which has made me wonder whether he could be becoming paranoid or psychotic.

There have also been moments that genuinely scared me. Earlier I was trying to make coffee and he was holding my hand. He wouldn’t let go while he cleaned the entire sink, even though I wanted to move away. He kept reassuring me that everything was okay, but I eventually became scared because I couldn’t get out of his grasp.
Similar things happened a few times while we were on ketamine where his demeanor, attitude, or the things he was saying suddenly seemed to shift, and I would have an enormous panic attack.

One thing making this especially concerning is that he has a history of a very serious psychotic episode while using psychedelics that resulted in violence and incarceration. I don’t want to give identifying details, but knowing that history makes the current sleep deprivation, heavy ketamine use, unusual beliefs, and increasingly manic behavior frightening to witness.

At the same time, we’ve also had some incredibly beautiful experiences together with psychedelics that felt deeply healing, which has made this emotionally confusing for me. I care about him and don’t want to unfairly label everything he’s experiencing as psychosis just because I’m scared.
I’ve also been pretty isolated lately and haven’t been talking much with friends, a therapist, or other outside people, so I realize I’ve lost some perspective.
I’m stopping the ketamine and reaching out for real-world/professional support. I’m also taking my physical safety seriously.

I’m mainly wondering if anyone here has personally witnessed something similar:

Can several days of heavy ketamine use combined with almost no sleep trigger mania, paranoia, delusions, or psychosis?

If you’ve seen ketamine-induced mania/psychosis, what did the beginning of it look like?

Did the person recognize that something was wrong, or did everything they were thinking feel completely rational to them?

What happened once they stopped using and finally slept?

I’m not looking for a diagnosis. I would just really appreciate hearing from people who have actually experienced or witnessed something similar while I seek professional help.

i feel like i need to ask for help maybe me n my partner been doing ketamine together and have been getting in k holes for almost 5 days straight this was after a big fight as well my mental health has already been unstable when we met i was having a hard time as you know and that thing happened at hanalei and he had a history of being in jail due to psychosis on mushrooms and bashing a cops head in and breaking their scull im having a hard time wrapping my head around this and im scared for my life and situation sometimes because of my history being around mentally unwell and my partner had been taking a lot more k than me throughout these days like during the day and stuff and is acting increasinly more manic its been so scary cuz i havent been in contact w friends or a therapist or really anyone and had some amazing the most amazing psychedlic and healing experiences w him but also he is barely sleeping and cleaning the whole house super ocd and earlier when i tried to make coffee he was holding me hand and wouldnt let go till he cleaned the whole sink and then was like no dont worry its ok and like wouldnt let me out of his grasp for a second till i got scared and thats what would happen a few times on the k hed say something or an attitude would shift which would trigger a huge panic attack for me he talks about getting nano tech off the body and like its just been a lot i dont know what to do in this situation

Sorry i used ai to help me write some more of my questions as I’m honestly just a little scared trying to wrap my head around this all right now

**Has anyone experienced ketamine + severe sleep deprivation causing mania or psychosis? I’m scared and trying to understand what’s happening.**

I’m posting because I feel isolated right now and could really use insight from people who have experience with ketamine, K-holes, mania, or drug-induced psychosis. I am also looking into professional help I know Reddit can’t diagnose this situation.

My partner and I have been doing ketamine together for almost five days, including repeatedly going into K-holes. This started after we had a really intense fight. My mental health was already not in the best place before this, and I realize continuing to use ketamine in that state was probably not a good idea.
My partner has been taking significantly more ketamine than me, including throughout the daytime, and has barely been sleeping. Over the last few days his behavior has become increasingly intense and what looks to me like manic or obsessive behavior. He has been cleaning the house almost nonstop and getting extremely fixated on things being a certain way.

He has also been talking about things like getting “nanotechnology” off of the body, which has made me wonder whether he could be becoming paranoid or psychotic.

There have also been moments that genuinely scared me. Earlier I was trying to make coffee and he was holding my hand. He wouldn’t let go while he cleaned the entire sink, even though I wanted to move away. He kept reassuring me that everything was okay, but I eventually became scared because I couldn’t get out of his grasp.
Similar things happened a few times while we were on ketamine where his demeanor, attitude, or the things he was saying suddenly seemed to shift, and I would have an enormous panic attack.

One thing making this especially concerning is that he has a history of a very serious psychotic episode while using psychedelics that resulted in violence and incarceration. I don’t want to give identifying details, but knowing that history makes the current sleep deprivation, heavy ketamine use, unusual beliefs, and increasingly manic behavior frightening to witness.

At the same time, we’ve also had some incredibly beautiful experiences together with psychedelics that felt deeply healing, which has made this emotionally confusing for me. I care about him and don’t want to unfairly label everything he’s experiencing as psychosis just because I’m scared.
I’ve also been pretty isolated lately and haven’t been talking much with friends, a therapist, or other outside people, so I realize I’ve lost some perspective.
I’m stopping the ketamine and reaching out for real-world/professional support. I’m also taking my physical safety seriously.

I’m mainly wondering if anyone here has personally witnessed something similar:

Can several days of heavy ketamine use combined with almost no sleep trigger mania, paranoia, delusions, or psychosis?

If you’ve seen ketamine-induced mania/psychosis, what did the beginning of it look like?

Did the person recognize that something was wrong, or did everything they were thinking feel completely rational to them?

What happened once they stopped using and finally slept?

I’m not looking for a diagnosis. I would just really appreciate hearing from people who have actually experienced or witnessed something similar while I seek professional help.

we are all on the spectrum yes like were all either more on the depressed or manic side and its finding that balance never do k or psychedelics unless under medical or intuitive team. my ex partner & i were doing K together recreationally, tested, i had been suffering from severe depression and gnarly adhd symptoms couldn’t even focus on reading. i believe my partner was in the uprising of a manic bipolar episode. we both did the K five days in a row however he started abusing it morning noon night while i only used it at night, it was the most beautiful psychedelic healing experiences of my entire life. i slept a lot after each time. unfortunately as the days progressed he slipped, absolutely lost his mind completely started vacuuming his whole body hours on end, the entire house, crazy OCD like washing every single appliance, making little shrines out of every little thing. totally flipped on me became violent, i ran out of the house he started to even break my appliances. it was completely demonic i’ve never seen anything like it in my life. i got a restraining order and never looked back. the crazy part was i felt completely healed (i also went and got several deliverance prayers and a lot of healing in Jesus , had to renounce the pretty much satanic ritual i didn’t even know i was a part of , we were un equally yoked while i was fully focused on Jesus he was inviting in kundalini spirit and other things) but my brain fully healed from my su i ci dal thoughts and everything, i could read and understand things again ketamine greatly brought me out of my spiral, i was devastated to see it go the other way for my ex. i just pray for him, the substance abuse and maybe underlying bipolar or schzophernia got the best of him. after that i have had no desire for any substance like i feel permanently high in the best way like maybe its the happy kind of manic where i feel like i can see visions and cut through the darkness with the power of Jesus ha . but no seriously i’m going to write a book or tell this story more in depth some day. it totally healed my chronic daily cannabis use which that * was throwing me into a psychosis - but seeing that made me be like wow .. and he was 16 years older than me, had many more years of weed / shrooms / alcohol than me … but it scared me to absolute death and i saw if i continued with daily substance that was my future. these are strong medicines and absolutley doing more research and tailoring them to the best treatment for that individual do not ever do ketamine recreationally. any psychedelic honestly needs to be in a contained space with really deep intention. you enter the spirit realm and have to be able to come back down from it, some people stay stuck in it and that is psycosis. i feel like i landed on the perfect spectrum with it where i have no su i ci dal thoughts and absolutely no anxiety whatsoever (thats also just Jesus healing) it’s how you use these and they MUST be rooted in the most high God because on K you have to make peace with death which not a lot of us have. I really saw Jesus and biblical Angels and felt like God released me from it all. I took the right amount i needed (5 nights of heavy k holes lol) now i literally have no fear and i do feel like i have special powers of seeing the dark and light - that’s another “spectrum” to talk about - “psychosis” or “spiritual awakening” ? This talk blew my mind i want to keep in the conversation Ketamine is definetly so interesting and i noticed each night i took it it does kind of build up in the brain, like the journeys got signficantly deeper each time and things got clearer. I always had a strong sense in me that was like “that was the right amount” where previosly id stuggled with deep throating weed all day everyday my partner joked “ you just need to kiss the weed not deep throat it “ 😂 … then in our journey he just took more and more and more …. It was both the most psychedelic and healing experience of my life yet devastating .. we were only together 3 months i’m glad the Lord showed and protected me, i am glad i could at least bring Christ into his life. i’m so thankful i hit the sweet spot with K and knew when to stop. i pray for everyone here to find there perfect balance for brain chemistry, body and soul and Spirit ❤

i feel like i need to ask for help maybe me n my partner been doing ketamine together and have been getting in k holes for almost 5 days straight this was after a big fight as well my mental health has already been unstable when we met i was having a hard time as you know and that thing happened at hanalei and he had a history of being in jail due to psychosis on mushrooms and bashing a cops head in and breaking their scull im having a hard time wrapping my head around this and im scared for my life and situation sometimes because of my history being around mentally unwell and my partner had been taking a lot more k than me throughout these days like during the day and stuff and is acting increasinly more manic its been so scary cuz i havent been in contact w friends or a therapist or really anyone and had some amazing the most amazing psychedlic and healing experiences w him but also he is barely sleeping and cleaning the whole house super ocd and earlier when i tried to make coffee he was holding me hand and wouldnt let go till he cleaned the whole sink and then was like no dont worry its ok and like wouldnt let me out of his grasp for a second till i got scared and thats what would happen a few times on the k hed say something or an attitude would shift which would trigger a huge panic attack for me he talks about getting nano tech off the body and like its just been a lot i dont know what to do in this situation

Sorry i used ai to help me write some more of my questions as I’m honestly just a little scared trying to wrap my head around this all right now

Has anyone experienced ketamine + severe sleep deprivation causing mania or psychosis? I’m scared and trying to understand what’s happening.

I’m posting because I feel isolated right now and could really use insight from people who have experience with ketamine, K-holes, mania, or drug-induced psychosis. I am also looking into professional help I know Reddit can’t diagnose this situation.

My partner and I have been doing ketamine together for almost five days, including repeatedly going into K-holes. This started after we had a really intense fight. My mental health was already not in the best place before this, and I realize continuing to use ketamine in that state was probably not a good idea.
My partner has been taking significantly more ketamine than me, including throughout the daytime, and has barely been sleeping. Over the last few days his behavior has become increasingly intense and what looks to me like manic or obsessive behavior. He has been cleaning the house almost nonstop and getting extremely fixated on things being a certain way.

He has also been talking about things like getting “nanotechnology” off of the body, which has made me wonder whether he could be becoming paranoid or psychotic.

There have also been moments that genuinely scared me. Earlier I was trying to make coffee and he was holding my hand. He wouldn’t let go while he cleaned the entire sink, even though I wanted to move away. He kept reassuring me that everything was okay, but I eventually became scared because I couldn’t get out of his grasp.
Similar things happened a few times while we were on ketamine where his demeanor, attitude, or the things he was saying suddenly seemed to shift, and I would have an enormous panic attack.

One thing making this especially concerning is that he has a history of a very serious psychotic episode while using psychedelics that resulted in violence and incarceration. I don’t want to give identifying details, but knowing that history makes the current sleep deprivation, heavy ketamine use, unusual beliefs, and increasingly manic behavior frightening to witness.

At the same time, we’ve also had some incredibly beautiful experiences together with psychedelics that felt deeply healing, which has made this emotionally confusing for me. I care about him and don’t want to unfairly label everything he’s experiencing as psychosis just because I’m scared.
I’ve also been pretty isolated lately and haven’t been talking much with friends, a therapist, or other outside people, so I realize I’ve lost some perspective.
I’m stopping the ketamine and reaching out for real-world/professional support. I’m also taking my physical safety seriously.

I’m mainly wondering if anyone here has personally witnessed something similar:

Can several days of heavy ketamine use combined with almost no sleep trigger mania, paranoia, delusions, or psychosis?

If you’ve seen ketamine-induced mania/psychosis, what did the beginning of it look like?

Did the person recognize that something was wrong, or did everything they were thinking feel completely rational to them?

What happened once they stopped using and finally slept?

I’m not looking for a diagnosis. I would just really appreciate hearing from people who have actually experienced or witnessed something similar while I seek professional help.

I've been reading research suggesting that a lot of what is diagnosed as depression is actually driven by dopamine issues. This often in mammals occurs after abandonment (or perceived abandonment) because the body gives up as a way of protecting us from continuing to hopelessly seek our caregivers with the risk of attracting predators with our cries for help. That protective response drives a drop in dopamine and motivation, which results in symptoms that can occur in both ADHD and depression.

In particular this theory comes from the work of neuroscientist Jaak Panksepp, as described in detail by the wonderful and highly praised book The Hidden Spring. There are many things that I could link to in this post and I'm happy to share in the comments if needed but this is the core foundational work that has revolutionized the thinking of neuroscientists about the origins of human consciousness and our core motivational drives.

This very much aligns with my experience, as I was on various antidepressants for many years with little benefit but responded much more immediately to ADHD medication.

I have been wondering about the possibility that if we look beyond the labels of depression and ADHD, a lot of the treatment-resistant depression that ketamine is helpful in treating might actually be driven by issues with dopamine rather than serotonin.

This is also relevant to me because I've been reading in other posts in the subreddit that many clinics recommend skipping your ADHD medication on the day of your ketamine treatment because the effects on blood pressure can compound.

Since anxiety increases are something has been a challenge for me on ADHD medicine and as I navigate through trying to benefit from ketamine treatment, I've learned that blood pressure increases can also increase anxiety. For me this seems like further evidence that what I might actually be dealing with are dopamine issues that are being driven by what ketamine is targeting (glutamate).

I've reached out to the psychiatrist where I've been doing my ketamine treatments (and also getting my ADHD prescription) to discuss skipping my ADHD medication on the days of treatment as well as possibly reducing my dose of ADHD medicine to see if perhaps ketamine is sufficient for me in addressing the symptoms that are most concerning for me (the difficulty with finding the will to fully pursue life).

I've read mixed results from people also in the subreddit who have ADHD on the impact of ketamine treatment. Again I think it might depend on whether those diagnoses are driven by that same system of dopamine-induced depression or some other driver of ADHD.

I'm not a professional scientist or doctor but I feel like this hypothesis is worth exploring (and worth discussing in this community). I think that many of our diagnoses are based on old hypotheses about how the brain works that need to be updated by more current research. Dopamine-related depression might actually be separated out as possibly a third category that could overlap heavily with treatment-resistant depression.

Again this is consistent with the experiences of many people on this subreddit who have stated that as their depression has improved, their anxiety has increased. This could represent the seeking system coming back online after being shut down for protective reasons during periods of abandonment.

I would love your thoughts. I am not attached to any theory. I am interested in seeking the truth and healing.