u/idontcareaboutaus

Anyone have unexplained infertility followed by loss and still get pregnant again?

My story is a bit of a unique one and I guess I’m just looking for some hope. I’ve been trying for a second since end of 2023. Up until then conception had been easy for me. End of 2023 was a chemical followed by 2 years unexplained infertility. I had just about all the treatments, and medications. Never once saw a positive test in those 2.5 years

Finally in March I did my first iui and to my complete shock it was successful. Unfortunately we found out a little over 6.5 weeks it was a blighted ovum/loss. The loss process has taken 1.5 months already and I still haven’t even ovulated - the one thing that used to be clockwork for me.

Im just so terrified it’ll be another 2+ years before I get pregnant again. I have no clue what caused my infertility and what caused this random conception. I’ll do another iui maybe next month but I won’t be taking medication this time (there was a twin scare).

Has anyone had a similar story? Where they had unexplained infertility followed by loss and actually went on to get pregnant again?

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u/idontcareaboutaus — 4 days ago

Treatment plan TW success & loss

This whole journey has been so hard and my 1st iui did not go according to plan. I’m wondering if anyone out there has had a similar experience.

My backstory: summarized the best I could
1 living child, started ttc a second Nov 2023 got pregnant end of December 2023 which was a chemical. Then I took 3 months off and when I started again experienced unexplained secondary infertility.

June 2025 I started seeing a specialist. Clear tubes and hycosy. Semen analysis excellent. Hormones all good. No DNA issues on my end - husband still needs his.

October 2025 started letrezole cycles with timed intercourse and trigger. Body always had 2 follicles never had success. 1st iui march 13th. Letrezole 5mg. 2 follicles, very thin lining, excellent semen sample. To our surprise it worked. 1st positive test in 2.5 years!

Here’s the messy part: 5w4d ultrasound: tech thinks there are twins. I quickly realized how terrified we were of this. I would have to quit my job? Get a new car? Go in for 6 week 4 day ultrasound and tech now says “just kidding only one” and then it turns out to be blighted ovum.

Instructed to take miso pills. First round doesn’t work. 2nd round unclear. Follow up ultrasound looks good, big drop In hcg. A week later follow up hcg is up again. Needed a d&c.

I’m meeting with a new clinic to start a 2nd iui soon and I’m wondering about my next treatment plan. I’m not sure if I ever had twins? And I know letrezole works. But I can’t help feeling I’m doomed if I do and doomed if I don’t. I’m so afraid of another 2 years infertility.

Has anyone had a similar situation? I’m wondering if unmedicated iui would even work for me? But will letrezole lead to twins even with only 2 follicles? I’d love to hear your thoughts

reddit.com
u/idontcareaboutaus — 6 days ago