u/lunatic-chipmunk-17

My 3 year old border collie has had issues with bile vomiting after not eating for 8 to 12 hours. She has also had three severe bouts of gastroenteritis, once when switching her to a food with beef and twice when she scavenged elk poop from the yard. She has a sensitive stomach in general, even with treats. Her most recent food, which was not was WSAVA compliant (and I admit was a huge mistake) also had her throwing up partially digested food frequently. After all the necessary tests, the vet just recommended Hills gastrointestinal biome. She has been doing well on Iams Lamb and Rice, so I’m a little hesitant to change her again. What are your thoughts? I want to make the right decision.

After three months on low-dose methimazole, I developed an allergy. It started with some hives just on my lips along with swelling, then progressed to itching around my entire face, head and scalp, and culminated in hives. My endocrinologist took me off the Methimazole and is very hesitant to try PTU because I already have a bum liver. He is recommending RAI. I go for a thyroid uptake scan in two weeks.

I am just wondering if it’s worth seeing an allergist and trying to confirm that it is a Methimazole allergy. I hate to kill my thyroid based on an assumption. That said, as soon as I came off the Methimazole, the hives itching and lip swelling stopped. my husband says I need to exhaust all options, but I just don’t know if going down the allergist route, when I’m on a time crunch off meds, is worth it. Any advice or anecdotal info would be greatly appreciated!!!

And here we go.... scheduled the thyroid uptake scan so we can figure out dosing and move forward with RAI. 😬 My reactions to methimazole have been getting more serious, and with my liver history, PTU isn’t a great alternative for me. I’m also seeing an allergist next week because before I permanently evict my thyroid 😂, I want to be as sure as we can be that methimazole really IS what has been causing these allergic reactions.

The good news? I’m euthyroid right now, meaning my actual thyroid hormone levels are normal.

The frustrating news? My Graves antibodies — TrAb and TSI — have gone UP quite a bit since I was diagnosed three months ago. So between that, the medication reactions and my liver, waiting around hoping for remission is starting to feel a lot less realistic.

I don’t smoke, I have no signs of thyroid eye disease, and we’re planning prophylactic steroids as an extra precaution.

But the radiation precautions after RAI?

THAT is the part I’m dreading. 😂

Two teenagers. A husband. Five cats. A rabbit. A dog. And a JOB.

Exactly where am I supposed to disappear to?! 🤣

Graves’ disease really is the gift that keeps on giving.

I scooped up two vials on the pomegranate sale and they were delivered today. BUD is 10 four. How far realistically can we go past that? In order for me to use them I would need to go into early December.

I see my Endo for the second time tomorrow, although we message every 2-3 weeks when labs come in. Last tests (1 week ago) showed I am now euthyroid. I am feeling pretty good…. Down 41 pounds (172 to 131) on tirzepatide, no symptoms other than some heat intolerance. I take meth 5mg 5x weekly, which I think he will lower, 60mg propranolol ER which helps keep my SVT in check and my functional medicine doc has me on a synbiotic with b. longum, magnesium glycinate, amino acids, a multi without iodine, a low iodine, gluten free, dairy free diet, b12/B6 injections, and D3… all after lab work, of course.

I guess I just don’t know where I go from here….

3rd week on 10mg and I have my first side effect…. Allondynia. Do I need to lower my dose or ride it out? It’s fairly mild at this time.

I have been on low dose methimazole since May 15. My TSH, T3, and T4 are all in normal range.

This week I have had a couple new symptoms but I am not sure if they are related. I have had itching on my forehead, jawline, and behind my ears that goes away with Benadryl. I have also had a couple of hive like bumps on my lips pop up. And I have had a couple of instances of my skin being sensitive in spots. A bit like burning but it goes away in a few hours.

I see my endo on Tuesday for a 3 month follow up so I will talk to him then but it’s worrisome now.

… but I would rather throw away what’s left than use it. 4 weeks and 0 pounds lost (after losing 35 in 12 weeks on Zep and a local source). The PAIN from the injection made me cry, and no appetite suppression or food noise abatement. Ugh.

Do all of their formulations have B vitamins? Recent labs showed my B vitamins are high and so my provider would like me to use a compound that doesn’t have them. I am on week three of Hallandale, but oh my Go…… the STING and muscle pain is just getting to be too much for me.

My functional medicine doctor reviewed my labs with me yesterday. She is happy to see T3 and T4 trending towards normal and feels my endocrinologist is doing a good job managing the methimazole and propranolol. I am showing an insulin resistance/pre-diabetes (correlated to Graves) so we added a supplement called Metabolic Xtra to take with dinner. My CRP was high (also correlated to Graves) at 2.99 so we added Inflammatone. And my estrogen was high while progesterone is low, another Graves link, so she recommended DIM Detox to start with a script for micronized progesterone to keep on the back burner.

I was already started on a probiotic with bifidobacterium longum (Seed DS-01) and magnesium glycinate along with an iodine, iron, b12 free multi.

I am really happy to have gone the route of a functional medicine doctor (She is a DO) to work with my Endo and PCP. It great to have had tests that no one else ordered, a doctor who spends an hour with me each visit, and someone looking at the big picture.

Let me preface with this: I spent over half my career to date in pharmaceuticals and fully support traditional medicine. I take my methimazole and propranolol as prescribed. That said, I saw a functional medicine DO about a month ago. It’s a concierge practice and quite pricey. She started me on a probiotic with bifidobacterium longum, magnesium glycinate, and a multi with iodine. My Endo approved all these. But she also asked me to go dairy and gluten free. My Endo said there is no basis for it. She ordered tests, including hormone, which noted I am in late perimenopause. My Endo says they are probably not accurate as my thyroid levels are still not stable and will alter the tests. My liver enzymes are normal (so is cbc, the rest of CMP, and other tests but my bilirubin has gone up since diagnosis. Gilbert’s Syndrome was mentioned years ago. Endo is not concerned. FM doctor wants crap ton of liver tests. I am so confused.

I dont know whether to continue down the Functional Medicine path or not.

I am coming off Zepbound and Hallandale had a safety profile I was satisfied with. I just took my first shot and it stung pretty good. There is also a small red area and it’s a bit sore. None of that happened on Zep. Please assure me I am not going to die or anything, lol.

My bilirubin has been going up since starting on 4/25. Bilirubin was normal 4/24. I have lost almost 30 pounds since then.

ALL other tests (CBC, the rest of the CMP), iron, D, B12, ferritin, and more) are normal, including liver function, kidney function, and hormones.

My Endo is not worried. My functional PCP seems a little concerned.

Has this happened to anyone else?

I started about 10 weeks ago at 168 pounds. Two months prior I was in an all-time high of 172 pounds. I am 5 foot four and 49 years old. My original goal was 135 pounds and I am down to 141 right now. I am thinking of pushing it down to 130 which is still mid range BMI. How have you decided your final weight?

Coming off Zepbound…. I drew the Hallandale and it seemed a little bit thicker than the Zepbound. There was also a thick air bubble, maybe a gel bubble, that I couldn’t seem to get rid of. Even when I pushed it to the top and tried to plunge it out, the liquid went around it. I put the liquid back in the vile, repeated with another new syringe and same thing. Is that just how the texture is?

And I am nervous. I am coming from Zepbound, but hoping that Hallandale works because the cost is substantially less.