I started using OrderlyMeds back in February. I was happy initially when they were using CasaPharma. Then with my most recent order they used SmartPharmaRX and my meds arrived warm. I have no idea why this pharmacy did not ship it in a Styrofoam cooler with ice packs the way every other pharmacy ships tempature sensitive medication. They shipped in a regular polymailer with 2 ice packs sandwiched between some random padding. The pharmacy is in FL and so am I so you would think they'd have used common sense but here we are. So I called the pharmacy first to let them know the icepacks melted and my Semaglutide was warm and they gave me the run around not returning calls or emails. So then I asked OrderlyMeds to handle it and of course they also gave me a bunch of BS about how the medication is fine warm for up to 5 days. I'm done with them. I need to find a new company (preferably without a monthly membership) so please share if you have one you've been happy with and would recommend. Thanks

Just curious if anyone has skipped a dose and what to be on the look out for. I'm going on vacation for a week and was planning on just skipping this week while still watching what I eat. Any tips?

Hi! I was on compounded semaglutide from November 2025 to early May 2026. It was great while I was taking it and I lost about 30 lbs with minimal side effects. However, my husband and I are considering trying to start a family and so I made the decision to stop. Since going off, my hair has been falling out like crazy. I have never had shedding or been able to see my scalp like this before and I swear I’ve tried everything to no avail. Has anyone else had luck with restoring their hair to before the meds? I’ve tried taking iron supplements and other over the counter supplements for hair growth. I don’t want to start something like minoxidil that I’d have to stay on forever to maintain results.

Surprised I’m not finding more discussions on this. I was on compounded tirzepatide for a year and a month — down 60 lbs — and just switched three days ago to compounded semaglutide for cost savings and because I’m just trying to maintain at this point.

I had no side effects on tirzepatide and I know that side effects are reportedly worse on Semaglutide; unfortunately I’m finding that to be true. I have a bit of an upset stomach since the shot and I’m generally tired. I have to assume that I should give it a few weeks for my body to adjust. I was on 15 mg of tirzepatide where I maintained the same weight for about 3 months, and so they have me on the equivalent of semaglutide, which is 2.5 mg.

I’m curious if anyone can share a positive experience about the switch, if it took time to adjust, have tips on how to power through, etc. Or, if you experienced this for a while on the sema and made a switch back.

TIA!

Since I started semaglutide injections about 10 weeks ago for weight loss, I’m intrigued by the side effects, some of them good some of them not so good. But the one that has me amazed is that my joints feel ten years younger. I am assuming it’s due to the anti inflammatory side effects, but they are not achy and stiff and sore everyday like they were before, and that has been such a blessing. The only pain I really experience is brief muscle soreness from the intense workouts I can now do again - because my joints don’t hurt! Eventually I will go off of the semaglutide, but I hope my joints won’t go back to being achy and sore again, although I assume they will as soon as the effects wear off?

I accept my fault, i started with 0.25 dose, then i jumped to 0.75mg and handled it well, i then ended up taking 1 mg dose a month later, after that being over confident for weightloss. First day i started vomiting badly went to ER they gave metclopramide injection. for whole first week i had severe nausea, burping fullness to the point i couldn't drink or eat anything at all. i went to emergency 5 times in 10 days. They put me on iv electrolytes drips. cause i cant eat or even drink. Yes i cant even keep water in i am in very bad state.. nothing is improving. Its 14th day i asked doctor to admit me, i stayed 2 days in hospital , the doctors giving me same medication, omeprazole, metclopramide and iv. doctors arent taking it serious just putting me on ivs and metclopramide inj.. my nausea and fullness is still bad i cant drink water, very less and feel extremely nauseatic and food is out of question. nothing seems to be improving. Please if someone has similar case or suggestion please help. When will i heal😓😓😓 i cant take it anymore its too bad..

I was doing the semaglutide shot for about 2 months and did not liked the way it used to make me feel. Stopped cold turkey and now am really suffering of this so called anxiety spells, dizziness, shortness of breath, gone to the ER and nothing is wrong. Horrible diarrhea, my head feels too heavy, fast palpitations and just very tired by 2-3 pm. Has anyone else experienced this? I started taking magnesium and ashwagandha and that is helped me a bit. For those that have experienced this, how long does it last? When would i feel back to normal?

Hi all! I started on Wegovy for 6 months, then my insurance dropped coverage. I started with Mochi and have been with them for almost 2 years. I pay $79 a month for compounded semaglutudr and a monthly $99 membership fee, so about $180 a month. I'm happy with them, it works and I think it's probably one of the less expensive telehealth companies. But what is everyone else paying? I'm curious.

Trying to pick a telehealth program and WOW, to say there are a lot of options would be an understatement.... I'm struggling to figure out which one to go with

Some brands just give you medication, which of course is the main thing. However, others offer dietitian support and physician check-ins which I think is particularly helpful since losing weight often requires a mindset and habits shift. Quick fixes rarely work

Harbor is one. Ro is another. Has anyone found success with any telehealth providers? I would really appreciate the help!

Hi all. I have been on compounded semaglutide for about 1.5 years and I have lost 60 lbs. and am now at my goal weight. I have been getting the medication from Eden the whole time and up until the past few months that has been fine, but they have become unreliable and my prescription is due to be renewed. Is it easy to switch? Will I be able to switch if I don't have weight to lose anymore? I am on a maintenance dose. Would it be cost effective to switch to an FDA approved like wegovy? I am so confused, the landscape has changed since I originally started. I am paying about $200/month right now and my insurance doesn't cover.

I am trying to request a refill for Semaglutide. I am currently on 0.8 mg. What is the next dose I should request?

My semaglutide was stuck in transit. Its been out of the refrigerator for 13 days, unopened. The bottle was cool to the touch, probably room temp. I promptly placed in fridge.

I'm wondering if I'll be safe to use it. Anyone have any experience with this or any side effects, toxicity or injection site reaction from unopened, unrefridgerated semaglutide?

Thanx

Does anyone have any info or data on increased desire to binge eat? I’ve been taking compounded sema for 4 weeks now, worked great! 2-4lbs lost each week. That being said, I took my shot yesterday and craved sweets and bad food. This is very untypical for me! I eat a balanced Mediterranean diet and never had a binge eating problem. This feels like it came way out of left field!

My only thought is my desire to eat was greatly decreased so my caloric intake was really low most days, like 900-1500 calories per day. On the lower end all last week - so maybe my body was craving more calories? I have no idea.

I felt defeated today and also physically felt like crap because I ate foods I don’t normally eat like ice cream, cookies, and bread with cheese. Totally binged. I never do that! Don’t have a history of it either. I’m also a non drinker 30 days going strong.

Any thoughts or advice are welcome!

Hey, I should have my first shipment arriving tomorrow. First time trying this stuff. I know we have a multiple day campout / hanging with family this weekend where I'm assuming there will be a fair amount of food / beer. I also see that it takes a while before you start noticing anything. Should I take my first dose when I receive it tomorrow or wait until after the holiday weekend?

So i did some research and based on my weight this is what i got i need about .55-.9 grams of protein per my body weight or 187 grams a day equivalent to 45-50 per meal if I eat 4 meals a day. Hear me out here tho there are days like yesterday where I felt nauseous most of the day and had no appetite and the thought of trying to eat something made me squimesh. I took my shot last thursday so its not like I just took it. Honestly most days i really dont feel like eating but i do try to eat a dinner cuz i have to cook for my 9yo. I fir purchase some Atkins high protein shakes and oatmeal cups hoping this helps in the day. My question is how are u all getting that much protein and fiber in your diet daily?

Today is my birthday and I also received my first order of compounded semaglutide. I’m excited and I hope this gives me relief I’ve been looking for! If anyone has any tips for the first few weeks, I’m all ears as I’m not sure what to expect besides some nausea.

My name is Simar Bajaj, and I’m a journalist working on an NBC News story about people who stopped taking a GLP-1 for obesity, even temporarily, and were able to maintain their weight loss.

I’m interested in what that looked like in real life: whether you stopped suddenly or gradually, how you dealt with the return of hunger or food noise, whether the drug helped you make lasting diet/exercise changes, whether you worked with a clinician, and whether you later restarted, microdosed, or switched medications.

If this describes you and you’d be open to being quoted in a story for NBC News, I’d be grateful to hear from you — and connect over a call.

For transparency, I was previous on staff at The New York Times and am now working on this story as an independent journalist. I'm happy to verify my identity and affiliation — however you'd prefer. Thank you so much for considering!

I asked before if people would pay extra for unlimited pharmacist text support through a telehealth platform, most said no. So genuinely curious, what's missing for you when it comes to support on a GLP-1 through these platforms, if anything at all?