r/MenOnThePen

Hi all,
I took my first 2.5 mg dose last week and I’m scheduled for my second injection in a few days.

My endocrinologist prescribed me 10 mg pens so I can stretch them a bit in this early phase for cost reasons. Since the pen will last more than a month, I’m storing it in the fridge.

A couple of questions:

1. Before injecting, do you usually let the pen reach room temperature, or do you inject it straight from the fridge? Any practical difference in terms of comfort or effectiveness?

2. After attaching the micro-needle, I sometimes don’t get a drop to appear on the first try. The leaflet suggests doing a couple of priming clicks until a drop shows up. If I end up doing this extra priming before each injection, does it affect the actual delivered dose in any way, or is it already accounted for by the pen system?

Thanks in advance for any practical tips.

Took my first 2.5 mg Mounjaro dose yesterday.
Today I basically had very low appetite all day: small breakfast, small lunch, almost no real desire to eat. But tonight I still ended up eating two big plates of pasta, and now I feel a bit guilty.
I wasn’t really hungry when I sat down more habit than real hunger. I almost treated it like a test to see if I’d feel an immediate change, but I still ate more than planned.
How does it actually work day to day? Is it mainly appetite suppression that helps you stay in a deficit, or does it also change the way how you “burn”? thanks

Jan 3 2026 I weighted 351 lbs and took my 1st shot of 2.5, did 24 shots of 2.5 then started 5mg last week on July 3 2026 I officially lost 50lbs. On July 4 2026 I weighted and I was at 299lbs. I truly don't know the last time I weighted below 300 lbs, in the last 20 years. 49 more to go to my goal.

I believe I believe I would met those goals at first of June had it not been for having to skip 2 weeks of shots on a month and half period due to a cardioversion and an ablation.

Hey all. I'm a 40 year old 162cm (5'4) / 80-85kg man who is aiming for ~65-70kg, which is where I was ~10 years ago when I was a quite fit.

I've been asked to choose between Mounjaro and Wegovy. I have ADHD, and the main contributor toward with my overeating is empty calories from booze + bad food. Otherwise I have an average diet. I've tried naltrexone and other non-glp1 solutions, and have lost ~10kg over the last few years which seems to be partially be from the ADHD meds, in my case Vyvanse.

I've managed to bring in some pretty decent strength training over the last 3 months, rock climbing 3-4 times a week + some body weight, so I'm reasonably strong for my weight, just struggling to get rid of the fat.

My psych and GP have both said GLP-1 meds are suitable, but I am wondering how to choose between Mounjaro and Wegovy. I can afford either, but a cursory read made it seem like Wegovy had slightly more evidence for folks with ADHD, with evidence thin on the ground either way.

Would love some thoughts, or to be pointed toward further reading / etc.

Many thanks, folks.

So it’s been 26 weeks since I took Mounjaro and I haven’t really gained that much since being off it. I currently weigh 14st 0.3lbs (196.3 lb, 89.04 kg)

The last time I posted was 16 weeks ago and I weighed 13st 10lbs. (192lbs, 87kg)

Before I stopped taking it, I weighed, 13st 8lbs. (190lbs, 86kg)

So all in all. It’s going pretty well. I put this down to getting rid of any ‘safety clothes’ I had. So I’m mindful
When things are starting to get uncomfortable.

But I’ve decided to start up again. (For a bit.). I have this idea of getting down to 12st 7lbs. I don’t need to start it up just to lose just over a stone. I feel it really helps curb my bad habits. Such as binge drinking and it definitely curbs my coffee consumption. I have been told recently it’s possible I have ADHD and I remember being less impulsive whilst taking it.

It’s strange because in the time, I’ve been off it. I’ve encountered lots of people on it who are close to me. My mum has even said she’d be interested in taking it! But I have never told anyone I’ve been on it. Not sure why. I feel it’s personal? But I feel it could really help my mum. She was so against it around 6 months ago. But a family friend who is a doctor started taking it and her worries seem to have evaporated.

I have toyed with the idea of taking Wegovy. Especially the pills as they’re much cheaper. But I feel this far in the game it’s best to stick with what you know. Hopefully the introduction of pills will lower the prices of the jabs. But we can only hope!