r/MultipleSclerosis

Has anyone ever experienced anything like this?

I(31F) was diagnosed with MS at 27. No relapses since and I’ve been on Tysabri since dx.

For the last few months I’ve had the feeling of bladder “pressure” making it feel like I have to go more often. I don’t dribble or have accidents, and I don’t wake up at night to pee.

But I do sometimes have a weak stream despite having to go (especially in the morning).

I have a very large fibroid that I had a procedure done to shrink a year ago (it shrunk from 5 inches to 3) but my doctors (OBGYN, Urologist, and Interventional Radiologist who did my fibroid procedure) do not seem to think it’s being caused by my fibroid despite the fibroid being basically right above my bladder.

A few weeks ago, I started feeling “crampy” all the time- kinda like very mild period cramps when I am not on my period. It is consistent, all the time.

I had an ultrasound that said I am not retaining urine, atleast at the time.

My next step is probably to see a female urologist since the one I saw wouldn’t let me speak and just wanted to put me on medication without knowing why.

Dear god

Why are you doing this to me. Every day, every minute of my life is a battle. I just want to walk again, even if it‘s only 10 steps. I want to get rid of this f* wheelchair. I want to use a toilet like every normal, healthy person. I don‘t want to wake up every morning with all the fears and anxiety. I‘m not asking for a villa with swimming pool or mio. of cash. I just want to be the normal person I used to be 4 years ago. Why are you doing this to me god?

So it's l yawn after every 4-5 minutes.In an hour 10-15 times

Last year I got diagnosed in August. I have issue in balancing and walking and my right leg kinda stutter.

I want to ask if anyone facing constantly yawning issue or it's me only ..

I feel I sound crazy saying this.

It’s almost been a year since my MS diagnosis. I’ve been on Kesimpta since November 2025 as my first DMT.

My left calf/leg has been experiencing fasciculations for the last 8 weeks. No weakness but it feels sore and tight when I walk and it waxes and wanes. Never had this before.

Why in my right MS brain am I worried about ALS? I’m so nervous to walk into my appointment tomorrow and ask the question if that has been ruled out or not.

Wanted to find out if anyone else on here has a constant ear-ringing. From when I first wake, before my eyes have opened and crack apart the ‘sleep’ in my eyes, I hear the ringing. Throughout the day with vehicles, loud music and lawn care equipment cannot lessen the ringing. And when it’s time to sleep, that infernal ringing is the last thing I hear.

Been tested for tinnitus and that’s was negative. Thought I had too much built up earwax and that was another nope. My ear canals and drums are tiptop, possibly due to having an overly active immune system for 25+ years before dx. Anyone else have this issue, both ears constantly ringing? Thanks!

My dr is not recommending mein dmt right now.. i got diqgnosed with rrms last month.. he said he ll give me some injection monthly for 6 months.. (i got reaction to 1st line treatment and oral steriod did not show any improvement on MRI)

I've been beyond depressed after a few months of my Rituximab infusion and it's killing any kind of productivity I have left to study for any competitive exams and now I just don't want to anymore. It just feels like no one really understands :(

Hi all, I may be having a hysterectomy soon and I haven’t started my DMT yet. For me, the priority is the DMT since I’m having pseudo flares often and my inflammation is high. However, I am worried about immune issues and surgery. Has anyone here had surgery whilst on Kesimpta with lower immunoglobins? How did it go?

Hello, is anyone here battling obesity and how does it impact your MS symptoms? I am currently 260lb at 5'7" and I am trying to lose weight because I know my weight is causing a lot of inflammation which I feel. I am in the middle of a flare too :( I also have Hashimotos, insulin issues (no diabetes) and very low iron which I was told also contributes to keeping the body "fat". I am feeling totally hopeless at this point, it's like my body is constantly punishing me even when I desperately try to do something better for it, like count calories or workout, it just causes more flaring of my previous symptoms. I am waiting to get on a DMT which should happen next month. Will this help or potentially make it worse given how much inflammation I already have due to my weight? Has anyone had any success with IF (fasting) for symptom relief?

Hi everyone,

I got diagnosed with MS a few months ago. My most prevalent symptoms are excessive fatigue, vertigo, and numbness in my extremities.

It’s really the vertigo and fatigue that’s getting to me though. I get nauseas very easily now and throw up almost every meal I have, and when I’m not working I’m asleep.

It sucks because I love food, and I love being awake to have fun with my hobbies!

Does anyone have any “tricks” or advice they can give me on how I can manage my symptoms and my life a little better? I have no one I can talk to or ask about this other than my doctor, and it’s so difficult to get an appointment right now.

Thank you so much <3

Ok so i’m 6 weeks in now.

Every day. No day off. At least 5 walks every day. I am now up to walks in shops and now very light trails. Each walk now at least 10 mins. I am trying and succeeding (so far) to walk up very light hills. Walking down them a lot harder.

Happy to answer questions.

I would implore all people to try this.

Start small. It’ll grow.

Will I feel sick? Is it mostly ok? I get what the process will be at the infusion center, but how will I feel afterward? I get that it varies.

TLDR: Searching for others with similar experience relating to a GLP1 and MS.

 

Was anyone diagnosed with Optic Neuritis as your first ever MS symptom shortly (within 1-2 months) after starting a GLP1, specifically Zepbound? 

I [34F] started Zepbound in March 2025.  Two weeks after starting, I had eye strain and pressure, along with twitching/pulsing behind one eye.  I started to lose partial vision the next week. I didn’t know what was causing it and ended up at the ER in April 2025, where they diagnosed me with Optic Neuritis, and ultimately, MS. I don't recall any MS related symptoms prior to this event and I’ve been on Kesimpta since (stable/no relapses).

I was told the two weren’t related (starting Zepbound and being diagnosed with MS), as the only eye issues in studies for Zepbound were relating to strokes within the eye; however, I recently started Zepbound again July 2026 and have noticed the same pulsing/twitching in my other eye within a week of starting.  I’m thinking now this can’t be coincidental. 

I’m curious if anyone else has had a similar experience. 

My arm has been weak lately and doing stuff just sucks. Holding a 5lb item makes me nervous because I know I’ll drop it and typing like this just irritates me cause my hand doesn’t want to respond.

Add in some brain fog and forgetting words and I swear I’m about to throw something.

I’m just wondering what others have done to help with the inconvenience of their dominant hand not cooperating. Im at my wits end.

Hi everyone,
I just wanted to share how I’m feeling and see if anyone can relate or has been through something similar.
I have MS and I’ve recently been unwell with a respiratory infection. I was put on antibiotics and also had a high dose of steroids (prednisolone) to help with inflammation so I could travel as I could barely breathe . Doctors have now said my lungs are clear and my vitals are fine, so medically I’m improving.
But emotionally and physically I still feel really wiped out. I’m exhausted, still coughing, and I’ve spent most of today sleeping. I know infections can hit harder and last longer with MS, but I’m finding the recovery process really frustrating and a bit isolating.
On top of that, I’m feeling quite low and overwhelmed trying to think about getting back to work as I don’t feel fully recovered yet.
I guess I just wanted to ask does anyone else find recovery from infections or steroids really knocks them for longer than expected? And how do you manage the fatigue and emotional crash afterwards?
Any advice or shared experiences would really mean a lot right now.

For about a week now I’ve been having very brief electric shock-like sensations in my head that last less than a second. They come and go throughout the day. Along with that, I’ve been getting dizzy, and my brain feels really “off.”
The hardest part to describe is that talking, listening to people, or even being around others feels like too much pressure on my brain. Sometimes I also get a strange feeling for a second, almost like I’m disconnected or “high,” and it’s really difficult to explain.
Im on Ocrevus for around one year and already contacted my neurologist last week and he said he doesn’t think is a new attack but I’m wondering if anyone with MS has experienced something similar. If you did, what did it turn out to be? Im super anxious about it as I can’t even describe how it feels..

I have RRMS. I’m on kesimpta. I was diagnosed when I was 18 years old in 2024. When I was diagnosed I only had 2 lesions on my brain and it affected my left eye. When I got over the first relapse I was practically normal. I had a second relapse yesterday and it was severe. I now have quite a few lesions on my brain especially my brain stem and one on my spine. I now live with symptoms everyday. Leg pain from my knees down they ache all the time and can give a burning sensation. My balance is no longer great and can make the inside of my head feel wobbly if that makes sense? I notice that when I’m walking if I look at the floor it’s like my brain can’t keep up. I’m wanting to find the most healthiest way to live with my ms including diet so I can look after myself and prevent it from getting worse for as long ass possible.

It's been a minute. How have been? Could specifically be about MS or just life. Updates, progress, setbacks, woes, etc...all is welcomed.

I was diagnosed with Radiological Isolated Syndrome in 2024. I was in for an MRI and they saw white matter lesions, but I had no symptoms at the time. In the last 12 months though I have been experiencing symptoms such as leg and arm weakness and fatigue and at times some tingling and numbness although this doesn't happen quite as much.

One thing I have been experiencing though is muscle twitching or muscle fasciculations. I have mentioned it to my neurologist but she dismissed it and said it's not a symptom of MS. I'm not so sure . Has anyone experienced muscle fasciculations from MS? They occur in random locations whether it is my legs, arm, chest, stomach or face etc. This has been going on for approximately 10 months. Honestly it freaks me out. Fasciculations and weakness can also be symptoms of other much worse conditions such as ALS. I am thinking of asking her to send me for an EMG the next time I'm in.

Hello friends. Wondering if there’s anyone else out there in this tiny universe that has both of these diseases. My search within the MS subreddit came up with some old (8y) results for those that definitely had these. Thought I’d reach out and start again. Hoping to hear that I’m not the only one. 🥴
(At least not the only one still active on Reddit.)