r/TirzMaintenance

Taking GLP-1 when not overweight

I’ve been wondering about something and would genuinely be curious to hear what other people’s experiences have been. Do people who aren’t really overweight, but just want a little extra help losing and maintaining a few pounds, ever use Tirz on a longer-term basis?

I’m especially curious about people who only have a small amount of weight they want to lose. Since they don’t necessarily need to lose a significant amount, do they tend to stay at the lower doses like 2.5 mg or 5 mg, and basically use that as their maintenance dose rather than ever moving up?

I’m wondering if there are people who find that a very low dose is enough for them to gradually lose those last few pounds and then keep the weight off, or if most people eventually need to increase the dose even when they don’t have much weight left to lose. I’d love to hear from anyone who has actually been in this situation and what their experience has been with staying at a low dose over time.

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▲ 2 r/TirzMaintenance+1 crossposts

Finished Tirz

After reaching my goal weight on the lowest dose of tirz and feeling pretty miserable through all 42 lbs i decided to go on Glp1 for maintenence. It's compounded with B12. I took my first dose Sunday night and I feel nothing. I went on fat scientist and determined that I should take 13 units. The instructions on the bottle said to use 25 units. Since I ordered from a pharmacy that I had never of, Pharmaneek out of Indianapolis i thought that I should go with what fat scientist told me to go with. Anyone else have any dealings with this particular pharmacy?

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u/Impressive_Wash8288 — 1 day ago

First time trying to be in maintenance, gained 7 lbs.

I started using compounded tirz from Pom in early December 2025. I wanted to lose 15 lbs and I did, slowly, by mid April 2026. I also had SIBO and was on a low FODMAP diet for about 6 weeks. Once that went away, I resumed my normal diet.

When I was losing, I was taking 4.5 mg. I then switched to Trimi and went down to 2.5 mg to maintain but got very hungry. Went up to 3.0. I recently noticed that I’ve gained back about half of what I lost!! 😩 I gave myself 5 mg at my last injection.

When I get back down to my goal, is there a way to suppress my appetite enough so I am not gaining but also not losing? How do I figure out what the right dose is for me to do that? I’m new to this so thank you for your patience and help.

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u/CraftyEsq — 1 day ago

In maintenance but gained

I’m in maintenance using 5MG of ProRX that I had in my stash . I was at my goal weight of 105 but today was insane ! I could not eat enough at all!! I have eaten over 2000 calories today , 175 grams protein !
Thru this whole process which has been a year , I’ve never had a day like this !! I stepped on the scale to see 112.5 LBS !! I’m sick over this !! I feel bloated and fat and definitely don’t understand how my appetite got so out of control !! Is it the ProRX ? Because it’s beyond the Bud?? Idk … but this can’t continue !! I need to order again and also confused as to who and what pharmacy is best because I don’t want additives . My first experience was with Olympia and it was fabulous!! I’m confused , and nervous now that the Tirz I have left is not effective!!

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u/payrollbaby — 1 day ago

What to do

Hi everyone,
Happy to announce I’m 1lb from my GW. I’m nervous about maintaining. I’m currently on a 5mg dose. I’ve been splitting the dosage to take it 2x a week at 2.5mg. I’m not sure what to do. Should I stick with that or drop down to 2.5mg once a week. I’ve been eating fine but I do have to incorporate fitness. Im nervous about gaining weight back! If anyone has advice please let me know. Thanks!

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u/TrafficCompetitive72 — 3 days ago

Shot trackers in maintenance

I feel like maintenance is "polluting" my shot tracker with useless data not relevant to my weight loss since I'm not losing weight anymore. Should I go without? Will I miss out on useful information? Should I get a new shot tracker? Do you still use your shot tracker?

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u/Impossible_Bend_2969 — 2 days ago

Struggling with A LOT of hunger

Y'all this is hard. I need advice.

Started Zepbound 1/13/25 at 5'5" 207#, lost 30% of my body weight in just over a year and am maintaining around 145. I'm 55F.

My highest dose used was 12.5. My doctor wants me to maintain at 10 mg or less.

I have used both name brand Zepbound and compound (BPI & Hallandale) during my journey. I currently have 3 vials of BPI in the fridge. But I'm currently using name brand every 7 days at 10 mg.

I AM FAMISHED. This is not normal hunger at all. Today is my day 7 and I had a biting, gnawing hunger almost all day long. Yesterday was bad too. This is definitely a pattern and it's gotten much worse since titrating down to 10. Unless I gain a bunch of weight, I'm afraid my doctor will not prescribe 12.5.

So my question - can I take my 10 mg dose of Zepbound on my normal shot day and give myself a little booster, like 2-3 mg, of compound later in the week? Is there any problem with mixing name brand and compound during the same week?

Any other tips for keeping the hunger down would be appreciated. Yes I'm eating protein at every meal and snack, I'm focusing on good healthy foods, not a lot of junk, drinking plenty of water, etc. etc. I exercise 4-5 times a week.

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u/Suspicious-Loss-7314 — 3 days ago

Bout damn time

Been waiting for this!
HW 280
SW 265
CW 199

Yes I had to wiggle around on the scale to get this picture because it was bouncing back and forth between 200 and 199, but a win’s a win. Haven’t been in onederland since I was a kid. Amazing!

u/floatingfoot — 4 days ago

Best place to get prescribed Tirzepatide online in US?

Tried going through my PCP first and got basically nowhere, he wasn't comfortable prescribing it and referred me to an endocrinologist with a 4 month wait. I'm not doing that. I've been looking at online men's telehealth options that handle GLP-1 weight loss with actual licensed physicians, not some sketchy compounding gray zone situation and I want something with transparent pricing upfront because I've seen quotes all over the place, like anywhere from $200 to $500+ a month depending on dose. (Which honestly makes it hard to even comparison shop without booking a consult first, kind of annoying.) Anyone gone through a fully online clinic for tirzepatide and actually stuck with it? Specifically curious about places that do the blood work component and have real provider access if something goes wrong or you need a dose adjustment, not just a one-and-done prescription drop. Would really help to hear what platforms people found worth it for medically supervised weight loss online.

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u/Federal_Peach5946 — 3 days ago
▲ 2 r/TirzMaintenance+1 crossposts

Zepbound to Hallandale

This has been my first experience with a compound and I will say I did lower my dose so it could be my own fault but does anyone feel like Hallandale isn’t quite as effective? I’ve been playing with my dose to try to find the dose that works for me to make me not feel so hungry but also not lose weight anymore as I’m currently in maintenance but I just don’t really feel like the medication is very strong, again could be my own fault lowering my dose but opinions/experiences?

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u/imnoseyicanthelpit — 4 days ago

Maintenance thoughts

For those of you that have been at maintenance longer than 6 months. I've been at goal or lower for 6 months. My stats are - 77 F 5' SW:163 CW:103 GW:110-115

I have been on 7.5mg/wk for about 8 months and eating anywhere from 1000 to 1200 calories a day. I have 1 vial open BUD 7/5/26 with 2 wks left. Another 1 vial unopened BUD 7/13/26. And 2 vials unopened BUD 11/3/26. At 7.5mg I have 3 1/2 mos left at least. I'm about to order my next 3 mos of vials next week.

Due to continued weight loss, my thoughts are to decrease my dose to 5mg/wk and make sure to get at least 1200 cal per day because I am at 20 bmi and can't afford to lose any more weight. (wow - I never thought I'd say this)

At 5mg/wk this will push out the amount of medication farther. In the 20 months that I've been on Tirz I have not been concerned about going beyond the BUD.

Would you push off purchasing next week's purchase?

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u/pml727 — 4 days ago

Anyone experience this?

I had gone down to my goal weight in a year and a half. Maintained at 9 mg for months. Then I started gaining. I went up to 11mg over some months, and now I’m at 12.5. The weight is not coming off. I’m fussing over 5 lbs — but I liked my goal weight! Why can’t I get back there? I’m terrified that 5 lbs will lead to 10 lbs. you know the drill. Why aren’t I losing at 12.5??

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u/Sufficient_Bed335 — 4 days ago

Body Recomp while in Maintenance

Hello!! I realized that I am approaching my goal weight, but I don’t believe at that weight I will have lost the stomach and back fat that I’m hoping to eventually. Throughout my tirz journey, I have been strength training consistently, and would like to keep gaining strength, but I do not want to drop below my goal weight. Is it possible to be on maintenance, continuing to get stronger, lose fat but not lose weight? I plan on posting in zepboundathletes if I get approved, but I would love anyone’s insight on this

Edit: SW: 298.3 CW: 168.8 GW: 150
💉10mg

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u/AceofSwords00 — 4 days ago

Hit a new low.

I started my journey way in May 2025 at 205 lbs but my highest was 218. I started at 1.25 mg doses. Currently I’m on 4mg which is the highest dose I’ve been on. Today I hit a new low and I’m going to try and spread my shot to 10 days. My first goal was 170 which I attained last year sept 28th. I didn’t feel done so I said I would continue until it felt like my goal. I got to 160 in November, I stayed in the 160s until December then dropped into the 150s in January of this year. I hit 155 in Earky Feb where I have maintained 155-150 since. In the last 3 weeks I’ve gone down to a new low of 146 this morning. Even I know this is tettering on too thin so I’m going to stretch my shot to 10 days. Is there anything I should expect?

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u/Odd_Many5780 — 3 days ago
▲ 89 r/TirzMaintenance+3 crossposts

What food noise actually is, and why semaglutide quiets it

posted earlier but the link was broken.

"Food noise" gets thrown around a lot here, but it's not just a TikTok term anymore. A 2023 paper defined it as the brain overreacting to food cues to the point where you can't stop thinking about food even when you're not hungry. The 4pm "what's in the pantry" loop on repeat is basically the textbook example.

The part I found most interesting: researchers split food reward into "wanting" (the chasing and obsessing) and "liking" (actually enjoying it when you eat). GLP-1s seem to turn down the wanting a lot more than the liking, which lines up with what a lot of people here describe, where food still tastes good but stops occupying mental space.

The less fun part: it's tied to the drug being in your system. Half life is about a week, and in the big trial where people stopped, they regained roughly two thirds of the weight within a year as appetite came back. Not a willpower thing, just the chemistry leaving. Worth knowing so it can be planned for.

I write about this stuff and put together a full writeup with the actual studies linked (the definition, the cravings trial, the brain mechanism, what happens when you stop). Sharing in case it's useful.

Not medical advice, just what the studies say. Heads up that the link is my own site.

https://pepsmart.net/articles/what-food-noise-is-and-why-semaglutide-quiets-it

u/PepSmartOfficial — 7 days ago
▲ 9 r/TirzMaintenance+1 crossposts

2 years in… 🤷🏻‍♀️

I’ve been doing well, fluctuating within 4/6 pounds of goal weight. I realized I was usually sitting on the top of my comfort zone, so went up from my highest 5mg to 7.5… it’s been about 4 months and the vibe is the exact same! Like, exactly the same fluctuation? I am pretty active, eating most days the same… my telehealth is offering to go up again, but I’m hesitant, as I was on 5 for over a year with great maintenance. Do I trust the process at 7.5? Go up? I’m so confused. I feel like I was a super responder losing my whole goal weight with 2.5/5… now ?? Argh

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u/Personal-Guidance897 — 7 days ago
▲ 0 r/TirzMaintenance+1 crossposts

I can’t lose anymore weight

I switched from Direct Meds to BRELLO due to cost. I went from 190+ to 143. Since switching to Brello last year, I have gained weight and I now currently wanting 152. I’m taking 15mg. My diet is the same. Can anyone give me some helpful advice on what company to go through? My insurance won’t cover it. TIA

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u/Potential-Drop8645 — 8 days ago

Scientific reason to titrate down?

Hi all - is there any scientific reason to reduce your dose in maintenance? I haven’t seen that there is any benefit to being on less tirz during maintenance, unless of course there is a side effect that is unpleasant or weight loss doesn’t stop. I wanted to know if anyone knew of a scientific or medical reason to reduce dose.

I have been in maintenance for 11 months now and I did reduce my dose a bit initially because I kept losing weight. Once I plateaued, I didn’t reduce my dose any further. I just see a lot of people wanting to reduce to the lowest possible dose or to spread doses out as much as they can and I think that’s personal preference or money (obviously a higher paw is more expensive than a lower one).

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u/stacelet — 10 days ago
▲ 12 r/TirzMaintenance+1 crossposts

I’m trying to refill but my only option is Apothecary and I found this on FDA.gov

WARNING LETTER
WL # 717972
December 1, 2025
Dear Ms. Rana:
You registered your facility with the U.S. Food and Drug Administration (FDA) as an outsourcing facility under section 503B of the Federal Food, Drug, and Cosmetic Act (FDCA) [21 U.S.C. § 353b]1 on September 7, 2024, and most recently on January 11, 2025. From May 12, 2025, to May 15, 2025, FDA investigators inspected your facility, Apothecary Pharma, LLC located at 1913 Evans Road, Cary, NC 27513. During the inspection, the investigators noted that drug products you produced failed to meet the conditions of section 503B of the FDCA necessary for drugs produced by an outsourcing facility to qualify for exemptions from certain provisions of the FDCA. In addition, the investigators noted serious deficiencies in your practices for producing drug products intended or expected to be sterile, which put patients at risk.
FDA issued a Form FDA 483 to your facility on May 15, 2025. FDA acknowledges receipt of your facility’s response, dated June 9, 2025, and related attachments received July 17, 2025. FDA acknowledges that your firm ceased sterile drug production as of May 12, 2025, and notified FDA of an intent to resume sterile drug production on August 1, 2025. Based on this inspection, it appears you produced drugs that violate the FDCA.

https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/apothecary-pharma-llc-717972-12012025?utm_source=chatgpt.com

I know people say you don’t get apothecary, you will get PGRx but PGRX never been evaluated by the FDA.

u/kc567897 — 10 days ago