r/TirzMaintenance

I was 5lbs from goal weight dosing 9mg every 7 days when I had to stop meds for 2 weeks prior to rotator cuff surgery. I waited 2 weeks after surgery to resume and gained 5 lbs in that 4 weeks. I resumed at 7.5 when I reached my goal, I tried going longer before my next shot. I was able to go about 15 days in between each shot for the first 30 days. Food noise started coming back after 12 or so days so I tried upping my dose to 8. Still had food noise after 12 days. I upped to 9 mg and again I was able to go 15 to 20 days. That is now starting to trend like the other doses, food noise is returning in 12 to 15 days. I am thinking I might try split dosing, but I’m not sure how much at this point. Like most, I want my meds to last as long as possible, this has been an expensive journey. I will “test” some doses but if anyone has had a similar experience, I would appreciate your feedback.

I currently get my microdose from Ellie MD. I’m on month 2. Not really seeing results. I’m wondering if it’s the formula…. Any other online trustworthy places?

I recently reached my goal weight on tirzepatide, which I’m really happy about, but now I’m feeling unsure about what comes next.
For those of you who have reached your goal weight, what did you do after?
Did you stop tirz completely?
Did you stay on a maintenance dose?
Did you lower your dose or space it out every 10–14 days instead of weekly?
My biggest concern is that I’ve been losing a lot of hair, and that’s making me consider stopping. But at the same time, my hunger is already creeping back in and I’m scared of gaining the weight back.
I know everyone is different and I’ll discuss it with my provider, but I’d love to hear real experiences from people who are already in maintenance.
What dose are you on now, how often do you take it, and have you been able to maintain your weight?

Thank you!

Started at 220. Goal is 165. Been at 15.0 for the last 9 months. Zepbound for 7 months, compounded since 2 months ago. On the day of my weekly shot for the last 3 shots I’ve been at 166. In between I’ve been as low as 164, as high as 168. Today 166. My shot is tomorrow. Will do 15.0 again. Because I’m concerned about gaining if I go down to 12.5 since I’ve been up and down a few pounds in each direction lately.
When did you decide to try to titrate down (to 12.5, then 10.0, 7.5, etc), if you did?
What about those of you who stayed at 15.0?
Looking for the various experiences, knowing that it might be much different across the board. Thank you for any advice you can give.

So my maintenance is not truly established. Fluctuations (within 5 pounds) are driving me nuts. I’ve been told to chill, which is not in my nature. My goal weight is 120, and I’ve hit it a year after starting. Have any of you figured out what to do about food noise anxiety? I just can’t tolerate it when I gain a few and it comes back. This was before I Titrated up. That seems to be helping. I’m so freaked out about going back up, I’m back to weighting myself daily again. Anyone else going / have gone through this? How long before you all relaxed into maintenance?

Who has switched to twice a week dosing for maintenance rather than spacing out doses? How has that been?

I’ve been on Reta since beginning January and slowly increased my dose from 0.5 mg to 3 mg.

Context: I’m F, a fast responder, my blood pressure tends to run on the lower side, and my main goal was to get leaner, lose some belly fat, and improve insulin sensitivity.

Honestly, my experience has been a rollercoaster. The first 1–2 months were rough:
• extreme fatigue
• strong appetite suppression
• sensitive itchy skin
• increased heart rate (especially with movement, sometimes it felt like my heart would jump out of my chest)
• low mood, low motivation/anhedonia

It also made working out difficult because my heart rate would go up too hard and fast.

I lost around 8–9 kg in about 3 months.
Now that I’ve reached my goal, I’m considering switching to low dose Tirz mainly for maintenance, insulin sensitivity, and anti-inflammatory benefits.

The biggest reasons are the increased heart rate and anhedonia, which really affect my motivation, mood, and ability to work out or start tasks.

For people who switched from Reta ➡️ Tirz, or have experienced both, how was your experience? Did you notice:
• increased heart rate
• low mood/anhedonia
• bloating or inflammation changes?
Would you recommend Tirz over Reta?

Also, what starting dose of Tirz worked best for maintenance, insulin sensitivity, and inflammation?

I ran into an old friend who hadn’t seen me in a while. She is super-fit and athletic, plays on a tennis league in her 70s, etc. She marveled at my weight loss, said how amazing I looked and how good it must feel. She asked me directly if I was on a GLP-1 med, and I answered honestly, so far so good. She then went on to tell me about a daughter-in-law and niece who were obese, and how she WISHED they would just DO something about it! As she spoke her expression matched her words and showed just how revolted she was by them. It made me wonder what she thought about me before and the whole encounter just felt so disappointing. I think some people will never understand the struggle, and obesity, unlike meanness, isn’t something we can hide. It’s there for all to see and judge. The ickiest part for me was the idea that now that Im not obese, I am welcome to the club where other peoples’ bodies are discussed and judged and “we” can all agree how pathetic they are. No, I don’t want to be in your mean-person club!

For those that spread out your dose- how frequently do you inject, and did you space out your dose slowly over time? Or do you just take it whenever you feel that food noise/cravings start to come back ? Edited to add that I am in maintenance.

Hello, now that the quickpen is on the American market how many folks have run the numbers on the cost of click counting vs compounding for maintenance level dosing?

Hi, I’ve been on maintenance for a few months and I like how it’s going but ready to save $$$, can’t do $450/mo anymore. Anyone else doing something similar that can give any recs?

- currently take my 10 mg vial about every 10-12 days depending on how I’m feeling. But I’m seeing the compounded vials have to be used every 28 days so this wouldn’t work the same if I switched ?

Is there something I’m not understanding right on the vials/dosages or something that anyone could recommend? I’d like to still keep the same dosage and schedule but is there an equivalent in how compound pharmacies can have this work for me? TY!

With all of the changes in the landscape recently which pharmacies and tele-health companies are offering the current longest BUDs?

For maintenance, how do you manage the ordering? Continuing to order every 3 or 6 months will grow your inventory faster than your use if you are not taking as much or spreading out your doses. And ordering monthly gets you bad prices. What's your ordering strategy?

Almost 2 years in and maybe a poster child for Tirz, lost 100# in one year going from 274 to 174, fairly happy and content with where I am but have been stalled for a year - really wanted to to get to 160# and a "healthy" BMI for once in my damn life!

Fast forward to now after lots of research I have added Reta and am seeing a bit of gain which I know is common initially. Curious at such point should I get concerned and realize maybe my protocol isn't working? Im up 6-8lbs in 6 weeks. Im also taking NAD+ and KLOW.

Anyone have similar issues, recommendations?

Hi. I'm on my 3rd week sa Tirz. Pero my weight since last week hasn't move. Is it normal? Should I continue with my 2.5 mg until 4th week?