I took my shot this morning, 40 units, and went for a walk in my neighborhood. There were some cops at the neighbor's house and they were eyeing me suspiciously when I walked by. I think they knew. I'm pretty sure one of them said "no viles" when I went by with his hand near his gun. I was so scared. Be careful out there!
I feel like maintenance is "polluting" my shot tracker with useless data not relevant to my weight loss since I'm not losing weight anymore. Should I go without? Will I miss out on useful information? Should I get a new shot tracker? Do you still use your shot tracker?
I took .15ml and .3 and feel nothing. I lost no wait. I'm still hungry. I took 30ml. Can I take 5l tomorrow, what do you think? I'm very disappointed.
I mixed 1 gram of cosmetic grade GHK-Cu powder into 1oz of Neutrogena Hydro Boost hyaluronic acid serum. The consistency of the serum was sort of viscous but more like a liquid than a gel. I put a small amount in at first just to check that it would dissolve. It appeared to sort of rest on the surface but when I turned the bottle to look inside, I could see tendrils of the powder dissolving into the liquid, swirling like smoke. It looked really cool.
I poured in the rest of the GHK-Cu powder and shook the container lightly to mix. It mixed very well and turned the liquid a deep cobalt blue. But it also turned the liquid more into a non-viscous liquid. It is not gel-like anymore. I think it will still work fine, but I was amazed how it changed the viscosity of the liquid.
I've purchased two other products from other companies that came with supposedly 1% and 2% GHK-Cu concentrations already added. I'm not sure how they calculate the percentage. The color of these serums is much paler than my 3% concentration. The 2% product was lighter than the 1% and nearly colorless. I used this post from Anela for the amount of GHK-Cu to add to the serum to make mine.
Triz changed my life. It fixed so many things. So greatful.
I am in maintenance on 7.5mg weekly. I used BPI for all my weight loss (and a couple vials of gray.) It always felt the same. I opened my first vial of ProRx last week because I didn't have enough BPI for my full dose. I took 2.5mg of ProRx and 5mg of BPI. I was floored. It felt like I was brand new to the medication again. I had no appetite. I had diarrhea two days in a row. I had the weird taste in my mouth and the other weird feelings I kind of forgot about since I haven't felt them in a while. It appeared I lost 4lbs, although my scale was acting weird so I'm not sure. I'm afraid to take a full 7.5mg tomorrow. What would you do? Take only 5mg? Maybe it was a fluke?
B6 seemed like a bad idea so I tossed my vile without trying it. I threw out some glycine viles too. Don't get mad at me for not being one of the poors like all you fatties. I don't have time for bad triz. You can never be too rich or too thin and I'm both.
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I have been struggling with runny nose and post nasal drip for a long time, especially when I'm outdoors walking. I come in contact with a lot of plants and get allergies from some of them. I heard about luteolin somewhere and looked it up. It has anti-histamine properties and there's evidence it provides relief to people with mast cell activation syndrome. Luteolin can stabilize mast cells. I've tried it now for a few weeks and it works really well. I have been able to breathe through my nose out on walks, no constant runny nose and post nasal drip. It's been amazing. I am going to see if I can stop taking claritin, too. Claritin never really helped much, and neither did flonase or breathe rite strips. I've been taking the liposomal type, not the white capsules.
I'm struggling with body image. I have not been in maintenance very long. I'm a pound over my goal weight, which is frustrating. I think I can see that pound as giant fat blobs of inner thigh fat when I'm sitting on the couch. I feel like when I look in the mirror I've got my same old overweight body. I start to feel uncomfortable in my clothes even though they fit the same. I know none of this is true. I lift weights 2x/week, will try to squat 25lbs over my own body weight on Tuesday and probably succeed at it. I'll try to do some chin-ups tomorrow and probably be able to do two in a row. I think I'm staying within my TDEE but the calorie tracking, which I didn't do during weight loss but am now doing in maintenance, is making me a little nutty. Some days I go over and I think I'm doomed. Some days I go under and think yay me! Which is dumb. I'm doing okay physically, but I just don't feel like I am mentally and I don't see what I used to see.
I've always loved long distance backpacking and would like to do a trip longer than 5 days. I'd like to go hike 500 miles of the Pacific Crest trail.
I have reached my goal weight recently and still use tirzepatide in maintenance. I haven't done anything quite this extreme since I started. This isn't quite the same as something like a marathon or an ultra but it's sort of similar. I'll probably hike about 20 miles every day for close to a month but it's not a race and 20 miles can be done at a comfortable pace.
Do you have any tips for dealing with something like this? I suppose it will come down to playing it by ear.
I just don't have very many before pictures and of course none of them are revealing. I found this one from last year and I took the after picture today. When I would hike before, my thighs would rub together. Now my thighs don't feel like they rub together at all. I can't wear those orange shorts anymore. They fall off.
In the before picture I was around 150lbs and now I'm 120lbs, my goal. I'm 5'3" and 61 years old.
I went on a 5 day solo backpacking trip. I timed it so I wouldn't be out there on shot day, or if I was, my shot would be delayed only a day or two at the most.
I started my trip with med levels at the peak. My biggest worry was what backpacking with medical appetite suppression would be like but it was not bad. I was never sure if low appetite was because of my shot or the altitude. I just made sure to eat all the allotted food for the day. I am only 2lbs down after this trip. Some of this could be water.
I wasn't planning to climb Whitney but figured I was in the area so why not?
It was a long climb and an effort but I felt like breathing wasn't a problem. I felt strong and didn't need to rest or catch my breath. Whitney is 14,505 feet.
Overall, not hauling around extra body weight was a great experience. My legs don't rub together anymore! Lifiting heavy--squats and deadlifts--and just walking around my city at sea level was enough to get in shape for this.
I am basically in maintenance (what does that even mean if you are always trying to improve physically?) and this was my first time since starting Tirz doing something like this.
I posted the other day about feeling my tirz wearing off. I took your advice and increased. I went up from 6.5 to 7.5mg.
It took a few hours but I could slowly feel the calm coming back. I could feel the hunger dissipate. I was left with an almost sore feeling in the place where I feel the hunger. It took about a day to feel tirz-normal again, but I still really really wanted cookies. Two days to feel like the inflammation was gone. I took a measurement to compare and lost about half an inch off my thigh. My ring is back to being loose again, easy to take off. It doesn't feel like a new dose. It feels like the old dose back again.
I didn't start split dosing. I may try that next time I need to increase. I can't see how I will be able to avoid increasing during maintenance. Has anyone else needed to increase? How much have you had to increase over time? Did you ever reach a dose you can stay on comfortably? Or do you just get to the max and then what?
I'm kind of disappointed because I did not lose as much as I hoped for and now it doesn't feel very permanent.
I take 6.5mg once a week and I've been taking it once a week. My weight has been stable for a month.
It feels less and less like there is any tirz in me. My appetite feels like it has returned. I've found it harder to stay out of the cookies and snacks this week. It is harder to eat enough to feel satisfied. My ring used to feel loose and now it is tight again, my feet are starting to hurt again, my ankles seemed puffy today. I think the anti-inflammation has worn off. I was so hungry today. I feel like I used to before Tirz.
Is this how maintenance feels? Like back to how it was before? I'm not sure I like this.
I saw my goal weight at the doctor's office today. 120.2lbs wearing shoes and a heavy hospital gown. This is after a night of colonoscopy prep. Barely counts but it's nice to see it! Almost makes the procedure a good day.
I'm considering asking them what they think I should do just to see what they say. But I'm worried that if I tell my telehealth I'm ready for maintenance that they'll start bossing me around on my dose, not let me change it if it's not working out and I need an increase or make me take a lower dose. I know they can't make me do anything, but I don't want to have them basically be dead to me as a source in the future because they insist I can only purchase 2.5mg from them in the future.
https://medicalxpress.com/news/2026-05-tirzepatide-full-dose-weight-loss.html
It was a 112 week study with people in groups that would continue their dose in maintenance, reduce to 5mg or placebo. MTD is maximum tolerated dose which had to be 10mg or 15mg for the people in the study.
>Between week 48 and week 60, bodyweight plateau occurred in 84%, 83%, and 85% of participants randomized to continue tirzepatide MTD, reduce to tirzepatide 5 mg, or switch to placebo, respectively. Studying those who reached a weight plateau allowed the researchers to assess the weight maintenance phase in a weight-stable population.
>Among participants who reached a bodyweight plateau, those continuing tirzepatide MTD maintained 96.5% of bodyweight reduction obtained during the weight-loss period and those who reduced to the 5 mg tirzepatide dose maintained 67.9%, versus 42.8% with placebo.
This seems to say on average you're better off just continuing your dose in maintenance than reducing it. I'm sure there are always some people who will continue to lose and need to reduce dose, and obviously some probably gained more than 4.5% in this study, but it sounds like on average it's better to just keep doing what you're doing.
This culture of not commenting on people's bodies at all is not something I like. Feel free to keep your mouth shut if you have nothing good to say, but not saying anything nice at all is bumming me out. I thought maybe nobody has noticed because my weight loss hasn't been super dramatic. I've lost 22lbs.
I was coming out of the store and a friend was coming into the store. He asked me if I was okay, that it looked like I'd lost weight. At first I was like finally, somebody noticed. I told him yes, I've lost some weight. But he was concerned I might be sick. So I said to him, I lost weight on purpose.
That kind of bothered me. Is it only okay to say something if you think someone is dying of cancer, so you can express sympathy for their illness? But not okay to make a compliment?
I don't think I look like I'm dying of cancer. Do you?
Today is shot day and I'm so happy because I just want to eat I am so hungry lately. It is wearing off. I don't want to increase my dose because I'm having a colonoscopy in 2 weeks. The monster inside has awakened and he says, "Maybe I should just eat all the cookies and forget about losing weight for a while. Ice cream should be safe to eat the week before the colonoscopy."
