If antihistamines help you with pmdd symptoms do you feel you have MCAS?
There is a theory on Reddit in pmdd communities that if antihistamines work for pmdd like symptoms, people have MCAS.
‘Mast Cell Activation Syndrome (MCAS) is a chronic immune system condition where mast cells—cells that help fight infection—overreact, releasing too many chemicals (such as histamine) too easily. This leads to repeated, severe, multi-system allergic reactions, including skin, gut, and heart symptoms, sometimes leading to anaphylaxis.’
https://my.clevelandclinic.org/health/diseases/mast-cell-activation-syndrome
u/Junealma — 13 days ago