r/PMDDxADHD

Hi,
I’ve been diagnosed with ADHD for about 5 months ago and now I’m wondering why I’ve been the way I’ve been
Is emotional dysregulation that normal? I wanna know your experience as a woman. How do you manage hormone, how are you navigating society stigmas and how are you managing corporate as well

Hi all—I was diagnosed with pmdd about eight years ago and just diagnosed with adhd (at 37) about five weeks ago.

I’ve been on Nikki (generic Yaz) for over a year and love that taking it continuously stops my period completely. I’ve also been on 10 mg fluoxetine since I was diagnosed with pmdd, first taking it just during luteal and now (post-pregnancies) taking it every day. I could list all my symptoms that led me to my adhd diagnosis but some of my biggest issues were distractibility (especially while driving), impatience, and emotional regulation.

I started Vyvanse (30 mg) mid-September. Had the honeymoon euphoria and felt amazing… for about four days. Then my period started (two weeks before the end of my pill pack) and it felt like the Vyvanse just quit. After two days I felt like the Vyvanse kicked in to about 20% but now it feels like I’m taking placebo pills. My period hasn’t stopped either, and although it’s not super heavy it’s definitely more than just spotting.

I’ve searched this sub extensively and read many posts that say adhd meds don’t work during luteal and/or during your period. The only thing that I changed is adding Vyvanse into the mix so I’m assuming that it kickstarted my period by interacting with my hormones? What’s confusing is that since my period hasn’t stopped, and I’m now ~10 days out from the end of my pill pack, I can’t tell if this is a case where the med isn’t working because of my period (even though it’s not my real period time) or if I’ve hit that time where my body has adjusted and I need to play with the dosing to find the right level?

My doctor is out most of the month so I finally broke down today after waking up to another day of bleeding and messaged the practice asking to speak with anyone else after the holiday weekend. I would just let it play out and try to deal until the end of my month but I feel like my very worst pmdd rage and inability to emotionally regulate is killing me. Usually when I’m dealing with pmdd I at least know it’ll pass as my “cycle” (on the pill) continues but it feels like everything is getting worse since my period is just not stopping.

Not even sure what I’m looking for, maybe just to rant, so thank you if you made it this far. I keep hoping that I’ll wake up and my medication will feel like it’s even at 50% and that my period will finally be over. I just feel like I’m circling the drain with it being a long weekend.

Does anyone have PMDD & Adeno? Just had a laparoscopy and a hysteroscopy for endo and adeno and the specialist surgeon was fantastic but has been very blunt about how the only options for adeno are hormonal or Hysto.

In the course of my PMDD treatment I have tried just about every hormonal interference and all of them intensified the PMDD to the point it was unbearable. Mirena, Yaz, mini pill, levlen etc. At this point im quite scared to add another one in as my pmdd is fairly well treated (fluoxetine and adhd medication) and I really don’t want to slide backwards.

Had anyone done Ryeqo who has PMDD as well?

Asking because I do (mild and transient). Aside from stress, my tics only really happen during certain months high in ragweed allergens, after smoking cigarettes, or after hanging out in very moldy enclosed spaces. This tells me there is some kind of immune or allergenic component, which implies mast cell activity. Coincidentally I also have MCAS, as I think a lot of people in this sub do too iirc.

There's a connection between PMDD and MCAS. Not always, but still notably co-occurring. I just learned that Isoallopregnanolone (Isoallo / Sepranolone) has been used as a possible treatment for PMDD, the mechanism being that it blocks the effects of allopregnenolone which forms from progesterone which is why the symptoms occur during the progesterone spike in luteal. Isoallopregenolone is also being studied for tourettes/tics and is extremely promising. I'm wondering if whatever imbalance is going on is immune dysfunction related given the PMDD x MCAS cross over, and given the correlation between stress/trauma and autoimmunity and that PMDD also has this stress/trauma connection.

To support that hypothesis I'm seeking PMDD people who also consider themselves to have some degree of tics/tourettes.

Anyone have experience with taking Mydayis and Prozac? Just started Prozac 10mg a couple of weeks ago for pmdd. I am praaaayinggggg it helps because the 10 days before my period are HELL and I don’t know who I am. I haven’t seen many people taking both of the meds I’m on together, so would love to hear someone else’s experience!

Some background: i have been with my husband for over a decade. We are in couples counseling (it’s been well over a year and not our first time). We have also been through our ugliest moments the past couple years but generally are making good progress and I do feel good about this progress.

Lately I’ve been more open with him about my thoughts and feelings (this has been a big CPTSD thing for me I’ve been working on in individual and couples therapy) which takes us to last night, when he expressed concern about the PMDD symptoms I was describing and genuinely seemed to want to know more.

Everything was good until he requested I start reporting to him, every day, what my emotions are and my sex drive. I tried to tell him this was unreasonable but he felt like it was completely justified. It just immediately made me feel gross.. I get he wants to understand how I feel and support me but now I have to report every mood? It makes me feel like “don’t make me think about how you’re feeling just tell me” and it really pisses me off.

He tried justifying it so that he wouldn’t feel rejected and I wouldn’t have to reject him. I told him that’s what therapy is for. I totally get wanting to understand a partners mood shifts but I also feel like, if I look pissed off then you can assume I am pissed off and also am uninterested in sex.

Am I being unreasonable in luteal right now lol or is this an absolutely absurd request?

(40F) Day one and two- the clouds parted and Angels sang and I could think for the first time I can remember in my 40yrs. I also take Kratom, but SO much less this last week and a half than I have in the last five years.
Day three: It works a little bit in the morning and by 1p, zero. I started thinking: Do I need a higher dose? Maybe I’m an ultra rapid processor?
Kratom curbs the anxiety break through and I have only taken it every five to seven hours (I’m thinking anxiety is all it’s really done for me in the five years, but the actual base ADHD coverage on the Adderall was a missing link)
My psych prescribed Prozac starting on day 15 of my cycle. But we wanted to see how this week went before starting that.
I’m a day or two away from my period.
Adderall will work again? This week has felt like a very slight change, with the exception of no major brain fog and no edginess and no breast tenderness (it’s usually unbearable at this stage, is that possible from Adderall?)
My best friend found that 10mg in the morning and a 5mg in the afternoon keeps it going all day and she can still be a good mom when she gets home.
I guess I’m trying to understand/get a read on:
Do my boobs really not hurt like normal for the first time in forever because of this med?
The very slight mood improvement is quite welcomed, anyone else?
Sex drive seems very low and emotional sensitivity is still high, your experience too?
And should I ask to bump up the dose next cycle before trying Prozac? My gut feel about Prozac has me anxious about it, so I’d like to find the right Adderall coverage and add Prozac if needed.
Thanks for any and all advice and feedback.