u/Life_Unit2344

I have MCAS and looking for a gentle way to reduce the histamine creating bacteria. Any suggestions?

I took antibiotics for hpylori last year in June. I started getting intense unexplainable symptoms.

Symptoms:
- heavy legs and arms
- dizziness
- weird sensation in my chest
- vertigo
- nausea
- hungover feeling in morning without headache

What triggers:
- talking
- walking
- exercising
- hot showers
- cooking
- concentrating on something work
- basically everything

What helped:
- Going on a limited diet helped. I did not know what was the trigger so I just did selective food items.
- nervous system regulation
- changing position: moving my chest, walking or even putting my legs up
- salt and being extra hydrated
- resting

After a year, I think I have MCAS. Low histamine diet, etc have helped. But I also think I may have POTs.

My questions :
- Do these symptoms match with POTs?
- what is the best way to diagnose. Tilt testing is not available in my area
- how can I find relief during flares?

Does anyone with Mast Cell Activation Syndrome wake up feeling almost hungover but different? No headache, just a weird body sensation, kind of like the feeling right after a tequila shot.

It only happens in the morning, and drinking a lot of water with electrolytes makes me feel normal. Curious if anyone else experiences this or knows why it happens.

For people with MCAS who also have slow COMT and MTHFR variants, what mast cell stabilizers tend to be better tolerated?

I tried quercetin and I am doing well on a low dose -250 to 300 mg but get jittery on higher doses. I think it’s not enough to stabilize my mast cells.

For people with MCAS who also have slow COMT and MTHFR variants, what mast cell stabilizers tend to be better tolerated?

I tried quercetin and I am doing well on a low dose -250 to 300 mg but get jittery on higher doses. I think it’s not enough to stabilize my mast cells.

I’ve been dealing with severe MCAS for about a year, and a few days ago I started taking Allegra. The improvement has been dramatic, for the first time in a long time, I’m able to do things that I couldn’t do before.

My question is: if I start doing more now because I feel better, could I actually be making my condition worse underneath?
For example, is it possible that my mast cells are still firing just as much (or more), but the antihistamine is simply masking the symptoms? Or does better symptom control actually reduce the overall inflammatory burden and make it safer to expand activity?

I’m trying to understand whether feeling better means I can trust my body more, or if I still need to be very cautious about overdoing it.

I’ve been dealing with severe MCAS for about a year, and a few days ago I started taking Allegra. The improvement has been dramatic, for the first time in a long time, I’m able to do things that I couldn’t do before.

My question is: if I start doing more now because I feel better, could I actually be making my condition worse underneath?
For example, is it possible that my mast cells are still firing just as much (or more), but the antihistamine is simply masking the symptoms? Or does better symptom control actually reduce the overall inflammatory burden and make it safer to expand activity?

I’m trying to understand whether feeling better means I can trust my body more, or if I still need to be very cautious about overdoing it.

Everything is a trigger and so is talking. Is there a way to train the body to normalize certain actions?

Or the only way is to continue stabilizing the mast cells?

I notice symptoms flaring from just anything during a flare. But when my body stabilizes, I am able to do the same activities without any symptoms.

I am on quercetin 250 mg phytosome from Thorne.

- Most days it is completely fine and helps me control my symptoms
- other days, it triggers a weird jitteriness at night or morning which lasts for a few hours

Should I push through it as it lasts only a few hours or go for an alternative.

Any suggestions on alternatives.

My gene test for comt etc is pending results.

I booked my initial consultation with Becky Campbell office.

I paid $200 and the fees included a 30 mins call + recommendation plan.

The person went into generating a large bill with multiple add ons and fees. She wanted me to pay then and there which seemed odd. Why would someone not give time before asking to pay a $1600 bill.

Additionally, I asked whether a recommendation plan was included (as it was mentioned on the website and she said for that you will first need to get the testing ($1600), which is still fair but then pay another $900 for consultation before we give you a recommendation plan.

I booked my appointment with Becky Campbell with a lot of hope and was likely ready to spend money , but it felt quite fishy.

What is the most reliable way to test leaky gut?

I have histamine intolerance but cooking all meals fresh is almost impossible for me.

I wonder if I freeze under 2 hours of cooking, will it still be low histamine? For how long can I freeze?

I have MCAS and histamine intolerance because of leaky gut. This happened after a strong course of antibiotic.

I have a suspicion that undigested food could be causing my leaky gut. However, I have no gut symptoms at all.

Could it still be because of digestion?

Any suggestion for a digestive enzyme. Looking for the most minimal formula as I react to almost all supplements.

My cat was diagnosed with asthma. She gets coughing once in a month or so which lasts a minute or so. Otherwise, she stays very normal.

We have also noticed persistent black booger in her right nose only since 2 years, along with a weird obstructed kind of purring.

The vet directly prescribed her: Fluticasone inhaler 125mcg (110mcg) - Give 1 puff using Aerokat spacer every 12 hours long term.

I want to understand if other cats who have asthma also take a similar treatment or are you using tricks like litter changes, removing fragrances first.

I am planning to get a second opinion, should we go to a vet or a lung specialist?

I have McAS/histamine intolerance because of leaky gut.

Is quercetin a good option to stabilize mast cells or can it come with its side effects. Any brand suggestion?

I am already on Vitamin C which helps quite a bit. I react to a lot of supplements.

I have histamine intolerance/MCAS like symptoms from leaky gut.

Lglutamine triggers my nervous system. Is IGG a good idea?

I was thing SBI protect which has serum derived bovine. I want to try it but want to make sure it does not trigger a flare up.

I have leaky gut but lglutamine triggers symptoms as my nervous system has been dysregulated because of histamine.

Any suggestions on how to heal leaky gut?

Developed severe histamine intolerance after antibiotics — looking for recovery stories/advice

About a year ago, after antibiotics, I developed what seems like histamine intolerance / gut-immune dysregulation / possibly leaky gut. My symptoms have never really been “classic allergies.” It feels more neurological/systemic.

Main symptoms during flares:
- feeling extremely hungover or poisoned/intoxicated
- brain fog
- nervous system dysregulation
- crying/emotional surges during flares
- heart rate spikes at times
- likely vasodilation, I call it the spell
- weird chest sensations
- heavy breathing, like minor difficult pushing down air into diaphragm
- previously had buzzing sensations, dizziness, heavy legs, nausea, and major food intolerances (these have improved a lot).

I have no gut symptoms but I do know it’s my gut causing this!

The biggest pattern is that it feels like a “bucket.” Everything adds up:
- stress
- talking too much
- warm baths
- working on laptop too long
- lack of sleep
- less water consumption
- spending several hours socializing
- basically just living life normally can trigger symptoms

The good news is I’ve improved massively over the year- probably 90% compared to the beginning. I tolerate almost all foods now, though I still stay gluten-free, dairy-free, no alcohol or outside food and low histamine diet.

Current supplements:
- DAO enzyme (especially during flares)
- Buffered Vitamin C 500 mg
- Magnesium glycinate
- Vitamin D3

I want to try L-glutamine again for gut healing, but every time I try it, it seems to dysregulate my nervous system more. I have also been recommended butyrate.

A few questions:

1. What treatments helped you the most?
2. Are there reliable tests for histamine intolerance / DAO deficiency / mast cell activation / leaky gut?
3. Is full recovery possible?