BAT for the SLS Control arm patients has failed 5 Trials in the last year / Aza+Ven has failed to increase survival in 3 phase 3 trials and 2 phase 2’s. - while we are seeing unheard of, extended miraculous survival in the SLS Regal P3.

BAT for the SLS Control arm patients has failed 5 Trials in the last year / Aza+Ven has failed to increase survival in 3 phase 3 trials and 2 phase 2’s. - while we are seeing unheard of, extended miraculous survival in the SLS Regal P3.

While we are seeing extended near miraculous ALL Pooled Survival in the SLS REGAL Phase 3
- nearly 40% Survival at 3 years - in a transplant ineligible, Post Salvage AML Second Remission (CR2) Population with a expected MOS of just 6-8 months.
BAT / Aza+VEN / Onureg + Venclexta FAILED to Increase OS in 5 TRIALS:

• VERONA Phase 3 $ABBV FAILED high risk MDS/AML Precursor
• VIALE-M Phase 3 $ABBV FAILED - AML FIRST REMISSION (CR1)
• VIALE-T Phase 3 $ABBV FAILED - AML Post Transplant Maintenance
• Opti-AML Phase 2 MDACC Reduced Intensity FAILED
• Paradigm Phase 2 AML Front Line Modified Dosing again FAILED to Increase Survival.

-- Details on each trial https://stocktwits.com/55X_ROI_Q1_2026 - scroll through for DD if you like money. SLS is about to Go Vertical ---

Paradigm P2.

Interesting Look at BAT / Aza+VEN vs Intensive Chemo 7+3
EFS / left Chart AzaVEN a bit better
OS / right Chart Intensive Chemo . . . much better than AzaVEN for OS

and of course Transplant // EFS and OS is the only real treatment option ... Until GPS.

https://preview.redd.it/djofgrx1awth1.png?width=1980&format=png&auto=webp&s=67754ca29997340c825a90f5d52c142068a63c1c

https://preview.redd.it/hc68grx1awth1.png?width=1698&format=png&auto=webp&s=a5b98b5f6bfc0e2b70e3a939ea8646865f0344cb

also, does everyone Understand the VDM Stat trial CONFIRMS GPS is 100% for Sure Golden? 18.6% Survival at 3 Years, Net Adjusted MOS of just 8-10 months....

net adjustments: VDM 16.4 months included the time required to obtain a second remission 1-4 months

Patients were transplanted at an exceptionally 50% high rate.

Patients Median age 58 is much lower than REGAL Patients 68 -70 average ... Age is the Number 1 Prognostic factor for Survival - more than any other - a full decade of youth nearly doubles survival. look it up.

if not let me know...

I've been here longer than most, if you like money, Scroll my posts, you will see SLS is the Investment opportunity of a lifetime.

- Imminent Gps P3 Trial data is worth 20x the current $2.3B mcap / $11.50 will be $120 and Climbing the Instant the market sees the data.
- Very similar to what just happened at $MRNA
and for those who may not know and want a hedge, (scroll my posts) the secondary asset SLS009 - the most selective on target and first ever SafeCD Kinase 9 inhibitor - is right now worth 2X - 3X the rigged Mcap.

reddit.com
u/Run4theRoses2 — 9 days ago

When you add up the dates below, it equals an 80th event Announcement and share price Launch - any day now

- while we wait Gps Phase 3 Results worth $25B -$50B to Big Pharma + 10x to 20x the Current manipulated $2.3B mcap / $11.50 Share Price . .. .

Be Holding -- this $11.50 Share Price is about to $125 and Climbing.

144 days Since the 80th Event May 11th

Its been 143 Days / 4. 7 months while we wait for 2 events

- 60th Event occurred Dec 10 - 2024
- 72nd Event occurred Dec 26 - 2025
• - • 12 Events in 12 months / about 1 event Per Month • - •

- 78th Event occurred May 11 - 2026
• - 6 Events in 4.5 months / 1 event every 22.67 Days - •

60th - Dec 10 2024 - 78th May 11 2026
18 Events 516 / 17 months for 18 Events
-- A little more than 1 event Per Month

Its been 144 Days / 4. 7 months while we wait for 2 events

u/Run4theRoses2 — 14 days ago

Beyond remission: Prolong survival and enhancing care in AML --- Oral Az Onureg BAT for CR1 Patients, MOS of 24.7 Months - adding Ven to Onureg in the VIALE-M Phase 3 FAILED to Improve Survival.

​Gps P2 in Cr1 >67.6 months.

https://www.youtube.com/watch?v=NEIGqF_vEl0 / direct Youtube Link. Can Use embedded Gemini for Translation - An exceptional discussion of the AML Remission Treatment Landscape, and confirms Gps Efficacy.

WT1 Cancer Vaccine discussion - Dr. is referring to Gps.

reddit.com
u/Run4theRoses2 — 14 days ago

Completed SLS009 Phase 2 AML-MR Data Published at ASH Last December - is already worth 2x the current $2.3B Manipulated mcap.

Completed SLS009 Phase 2 AML-MR Data Published at ASH Last December - is already worth 2x the $2.3B Manipulated current mcap.

• AACR Conference will be shining the Spotlight on 009
• Possible New Clinical PDAC Trial Launch Announcement w 3 AACR Abstracts

• 009 Now in Phase 2 AML-MR Expansion Trial at the Request of FDA:
• 80 patients
• Dual Arm
• Randomized and
• PIVOTAL* • with FDA Greenlight Data incoming next quarter – in Q4

Previous P2 SLS009 Data Increased Survival 4x / 50% ORR in END STAGE AML-MR - 50% ORR in Dying AML Patients!

--- we Absolutely Know 009 is going to BE SUCCESSFUL in Newly Diagnosed - Front Line and Ven Aza 1 Line Failed Patients.
- AML-MR is the most Dire of AML Prognoses, often results from other cancer treatment, chemo radiation.

• list FDA approved drugs based on Ph1/2 data like the trial 009 is now in.

“The FDA has asked tambiciclib’s developer to start a trial investigating the combination in front-line acute myeloid leukemia.“

https://www.cancernetwork.com/view/tambiciclib-plus-ven-aza-met-all-primary-end-points-in-r-r-aml-trial

https://preview.redd.it/17kx7iolgirh1.png?width=1158&format=png&auto=webp&s=d3f05761be08fafe893bbf117f5ce523d11e553c

• list FDA approved drugs based on Ph1/2 data like the trial 009 is now in.

https://preview.redd.it/fs7yqinugirh1.png?width=1582&format=png&auto=webp&s=5e513f020e14f53ab3ff72b40eafff311693ff15

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https://preview.redd.it/65v6ux9xgirh1.png?width=2030&format=png&auto=webp&s=dcc69328cc7193be2d300914371802e4514401ed

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u/Run4theRoses2 — 21 days ago

Paradigm Trial Data from Last Week AML - BAT - AzaVEN increased Event Free Survival but OS Didn't Move -- just like Dr. Yair Levy Dir. of Hematological Malignancy Research at BAYLOR MED stated - a while ago, AzaVEN is NOT DURABLE.

u/Run4theRoses2 — 1 month ago

#SOHO2026 MDACC Leukemia Chair Dr. HK Kantarjian founded Soho - he’s also the SLS Regal P3 Global Lead and Steering Committee Chair

Unfortunately-No AML breakthroughs, no good news or trial data / nothing to explain the miraculous Survival we are seeing in the SLS Phase 3 Regal patients.

Does everyone understand that Oral Aza+VEN IS THE (BAT) - Best Available Treatment for SLS Phase 3 Control Arm Patients - in Second Remission (CR2), ineligible for Transplant ?

AND does Everyone Understand Oral az+VEN - FAILED 3 Large Phase 3 Trials Conducted by $ABBV ? including Failing the VIALE-M Trial.

• VIALE-M - M for maintenance
- AML First Remission Patients CR1 ineligible for T - FAILED
• VIALE-T - Post Transplant Maintenance P3 Trial FAILED...
Meanwhile we are seeing MIRACULOUS EXTENDED SURVIVAL and
• Gps MOS in 2 Phase 2's for AML remission were +2x and 4x better than standard of care.

Onureg is SOC for Cr1 - mOS of 24.7 Months - Gps Ph2 in the same exact Setting was 67.6 months...

and adding VEN to Onureg did not Increase Survival - it is not complicated

YOU absolutely Know the 3 Drs' treating Actual P3 patients are correct when they stated BAT is dismal/ not durable / extremely poor.

—
This is Precisely what a LONG TAIL of Survivorship Looks Like in many Immunotherapy Trials

49 Patients REMAIN --- alive at LEAST 30 months...
-- Nearly 40% of these AML Patients In second Remission Unable to withstand Transplant ... - Unheard of / never before seen Miraculous survival - and we know BAT / for Control Patients - is Toxic, does not offer Durable OS, according to 3 Dr's treating actual patients , and BAT
FAILED
BAT for the REGAL Control ARM FAILED - 3 Large Phase 3 Trials conducted by $ABBV - it is not complicated - its Gps doing what its Done in all 7 Prior Trials, Including 2 PH2's For AML Remission Maintenance.

There is NO Survival for CR2 Patients on BAT past 24 months in ANY RECENT TRIAL DATA

https://preview.redd.it/9yuhpl50tpph1.jpg?width=810&format=pjpg&auto=webp&s=7db5f9a10b3cf95fda11525c75d10800e840c726

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https://preview.redd.it/7se40v7ltpph1.png?width=1210&format=png&auto=webp&s=1673c4a07ea23fc30a3b3fa1654bd47a11582a06

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u/Run4theRoses2 — 1 month ago

Gps +Keytruda Phase 2 results for Platinum Resistant Ovarian Cancer 18.4 month Median OS, longer than $IMGN Elahere 16.4 months MOS - that $abbv Bought for $10B . . . Gps has Proven effective in preventing relapse and Extending Survival in ALL PRIOR Trials, 4 Phase 2's and 2 Phase 2's for AML

reddit.com
u/Run4theRoses2 — 1 month ago
▲ 113 r/TheRaceTo1Million+2 crossposts

Gps - Revolutionary Immunotherapy for AML Remission Maintenance, Phase 3 Results are Now Due* and worth $50B to Big Pharma - this is the TRUE NORTH for $SLS Share Holder Value, $MRNA just added $40B to its Mcap in a Day for the Same Reason SLS is about to.

Dec 10, 2024 60th Event

- Jan 23rd 2025 IDMC Unblinded Interim MOS and IR Data

- Dec 26th 2025 72nd Event

- May 11th 2026 78th Event

- 60 -72nd 1 Event Per month, 72nd to 78th 1 event Per 22.67 Days

--- its Now Been 4months and Day since the 78th while w await 2 events ='s Any Day Now.

Gps - Revolutionary Immunotherapy for AML Remission Maintenance Phase 3 Results are Now Due and worth $50B to Big Pharma - this is the TRUE NORTH for $SLS Share Holder Value $MRNA just added $40B to its Mcap in a Day for the Same Reason SLS is about to.

The world's leading Hematological Oncologist, Dr. H. Kantarjian - the Chair of MD Anderson's Leukemia dept., is the SLS Phase 3 Trial Global Lead, and Steering committee Chair....
A Legend in the HemeOnc world, with 20 Fda approvals to his credit is bringing the SLS Phase 3 trial Home.

We have 3 doctors Treating Actual Phase 3 Trial Patients on the Record Stating BAT for Control ARM Patients is "DISMAL" "Extremely Poor" "not Durable"

Dr. Levy Said, Dir of Hematological research at BAYLOR Med. ... A Smart Knowledgeable doctor,

Ven+aza/deci MOS is dismal just 6/8 months.

the same thing dr. Tsirigotis Stated - MOS for patients on BAT is Extremely Poor - on the order of 5-7 Months.

Dr. Jamy - was asked Point blank, what is the longest survival he sees in his practice for Second Remission CR2 Patients - he states MOS is just 6, 7 months using BAT / aza +ven and "you will not see survival past 12 months.

We have at least 47 patients nearly 40% of the REGAL p3 enrolled population continuing to survive AT LEAST 30 months.

,What is Gps worth?
• 12.5K AML CR2/3 Patients Year
• 50K AML CR1 Patients Year
• xCCO Published Estimated Pricing at $300K Per patient
• Compounded by infinite dosing regime: 3 years CR2, 6 year dosing regime on avg. for CR1
• 300K Patients in Remission Right Now who'll benefit from Gps right out of the Gate.

$RVMD set pricing $39,800 per patient per month. $477,600 Y1 Rasonque

$ABBV / $RHHBY and $BMY who own Aza+VEN - the BAT for the CONTROL ARM PATIENTS - Know Precisely how their drugs work in AML CR2 Remission Maintenance.

- VIALE-M Phase 3 for CR1 Maintenance FAILED

Aza+VEN the BAT for the SLS Phase 3 Control Arm Patients in SECOND REMISSION (CR2)

FAILED a Large Phase 3 FIRST REMISSION (CR1) Trial conducted by $ABBV -it's not complicated.

- VIALE- T Phase 3 for Post Transplant Maintenance - Failed

- VERONA high risk MDS/ AML precursor Failed

- VIALE-C - FAILED

and 23% of the Patients taking Aza+VEN in the only Viale trial that succeeded Viale-A - Died from taking BAT - the BAT for the SLS Control ARM.

- VIALE-M P3 Combined Venetoclax with Oral Az /Onureg the SOC for CR1 Remission Maintenance - MOS 24.7 Months - Adding Ven did not increase Survival, added Tox.

Meanwhile we continue to see Near miraculous Survival among the remaining 47 patients - about 40% of the 126 enrolled.

Its Gps doing what its done in all 7 Prior Trials, including 2 Phase 2 Trials for AML Remission Maintenance - Prevent Relapse and Extend Survival - 2x 4x OS Benefit Directly correlated with Immune Response - very similar to the $MRNA cancer vaccine P3 that added $40B to its Mcap in a day.

Since the IDMC Unblinded Actual SLS P3 MOS Data January 23rd 2025
SLS Market Cap Value is up 1,200%, Share Price +900%, Cash on Hand UP 1,110% Institutional Funds invested up to over 300 holding 60% vs just 39 w 8%.

Smart Money Knows. it ain't BAT - its GPS..

We also have numerous Published Trials with supporting Data

- First Remission Landmark MOS is Just 17.3 Months ... CR1 Transplant Ineligible MOS is Just 17.3 months.

- Gps Phase 2 in CR1 was > 67.6 months

- GPs Phase 2 in CR2 was 21 months - in an older (74), ALL MRD+ much less healthy patient setting, who received Less Gps - a max of 12 doses in year 1 only vs 15 doses in Y1 in the P3 with Infinite Dosing beyond - 6 Doses in y2 + Quarterly booster in Year 3 + .

* all sourced data - lmk if you would like links.

and for the Skeptics : SLS009 the Only Target and First Ever Safe CD Kinase 9 inhibitor s Already worth 2x 3x the current short rigged $2.33B Mcap.

-- just the Secondary asset Phase 2 Published Data at ASH for AML-MR patients - the most Dire AML subset, was better than Magrolimab P1 AML-MR data that $GILD bought for $4.9B

SLS009 is now in an expansion phase 2 trial at the request of FDA:

80 patients
dual arm trial
RANDOMIZED

and PIVOTAL

with FDA greenlight data incoming next quarter – in Q4 2026.

Kinase Inhibitors are Blockbuster Drugs with Household names: Kisqali Verzenio, Ibrance -- Long List

Plus we already have P1 87 patient Safety/ data for PTCL/AML/DBCL and PDAC.

https://www.globenewswire.com/news-release/2025/07/15/3115485/0/en/SELLAS-Meets-All-Primary-Endpoints-in-Phase-2-Trial-of-SLS009-in-r-r-AML-and-Receives-FDA-Guidance-to-Advance-into-First-Line-Therapy-Study.html

​

​

​

​edit: Wall Street financial models have used theoretical wholesale cost estimates of roughly $470,000 to $475,000 for a full, personalized patient treatment course, though analysts emphasize this is a financial modeling assumption rather than a set retail price. [1]

​

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u/Run4theRoses2 — 1 month ago

$SLS P3 Timing - Any day.

Monday it'll be Day 105
Since the 78th event occurred May 11.

- Shorts Playing Russian Roulette Every day They Don't Cover is Another PULL on the Short Trigger

- and its Sweet Short Cherry Pie Time.
- SLS is IN A QUIET PERIOD.
- 105+ Days since the 78th Event

- 102 Beautiful Days of Survival --- with 40% of the enrolled patients who had a 8 month MOs with BAT/Soc continuing to survive at least 30 months - 40% at least 4x better standard.

• We saw a 31.6 Day Event Rate from the 60th event Dec 10, 2024 to 72nd Event Dec 26 2025.

• 22 Day Per Event Rate from the 72nd to the 78th...
its been 105... since the 78th May 11. .. .

This Manipulated $3B MCAP $15 per Share is about to be a $30B Mcap / $150 Per Share and Climbing.

Fda Registrational Phase 3 Results - will give Gps the fda green light to generate Billions in REAL REVENUE - worth 10 -25 x the current mcap.
Mark this post.

u/Run4theRoses2 — 2 months ago
▲ 255 r/TheRaceTo1Million+2 crossposts

$100k Invested in $SLS will be worth $1M to $1.5M - the instant the Imminent Phase 3 Results are Announced.

$mrna just added $40B in a day based on its P3 results,
Something very similar is about to happen with SLS.

A positive P3 result is coming, any day now, and it’ll give Gps the fda greenlight to generate $20b a year in real revenue.

That is worth a f ton more than the current $3b market cap.

It is not complicated.

reddit.com
u/Run4theRoses2 — 2 months ago

10Q - Nearly 3 Years of Cash and Still No 80th Event

Aside from seeing the eventual and inevitable < .47 HR

... we have the Best news SLS Investors and these AML Second Remission patients could ask for ... Another Day.

ANY DAY NOW...

92 Days Since the 78th and Still no 80th??

Miraculous Survival for the Second Remission patients
&gt;.. Well beyond even CR1 Patients with BAT..

Dec 2024 60th Event Dec 2025 72nd Event /// about 1 Per Month
Dec 26th 2025 72nd Event - May 11 2026 78th Event 1 Per 22 Days

its BEEN 92 DAYS / 3 months since the 78th Event ... Truly the Best news any of us could have gotten!

Gps Immunotherapy MOS is squarely in the Miracle Cure Class.

reddit.com
u/Run4theRoses2 — 2 months ago

" 78 Events have Occurred as of May 11th " • 90 Days Ago • Ceo disclosed a quiet period July 25th ... We Should See the 80th Event Top Line PR and Massive Share Price Launch with the 10Q This Week.

" 78 Events have Occurred as of May 11th "
Headline from the Last 10Q • 90 Days Ago

VOLUME SPIKED / and it didn't take long for the Share Price to Double...
• 72nd Event DEC 26th --- Share Price Doubled ... as well.

• 60th Event, Dec 10 2024 to 78th Event, May 11th 2026 - 572 Days
-•- 28.722 Days Per Event

• 60th Dec 10, 2024 to 72nd Dec 26th 2025 - 369 Days
-•- 31.6 Days Per Event

• 72nd Event, Dec 26th 2025 to 78th Event, May 11 2026 - 139 Days
-•- 22 days per event

its been 90 days - Since the 78th ....

Ceo disclosed a quiet period July 25th ... We Should See the 80th Event Top Line PR and Massive Share Price Launch with the 10q This Week.

https://preview.redd.it/nf3ne3ojkeih1.png?width=2154&format=png&auto=webp&s=9c85a957b1e0825355d797d59acb511c2915cdea

https://preview.redd.it/11dkphkfkeih1.png?width=2660&format=png&auto=webp&s=57ff1563fc261c1304957907186534c38a7231fe

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u/Run4theRoses2 — 2 months ago
▲ 21 r/MetalsOnReddit+1 crossposts

If anyone has ever heard of SLS, know - now is the time to be loading, or fully loaded and Hodling.

This short rigged $2.25B Baby Bio is about to Release Phase 3 Registrational Trial results for a Revolutionary Immunotherapy for AML remission maintenance, giving Gps the FDA Green Light to a $28B Total Addressable Market - worth every nickel of $50B to big pharma.

Do the Math: Load As many as you can.
Your future self will thank you.

• Gps will Generate Nearly $5B Per YEAR Just for the 12,500 AML CR2/3 Patients
• 12,500 Patients 34/36 Month Median OS
• 3 Year Dosing Regime
• Co Estimated $300K Rev Per patient year 1, $120K Year 2, $80K Y3
• 80% Patient Uptake Rates --- Just shy of $5B in Revenue
• Then ADD in 40,000 AML CR1 Patients Each Year
• 5 year Dosing
• +100,000 AML Patients Currently In Remission right now, who'll benefit from Gps Immunotherapy, right out of the GATE.

reddit.com
u/Run4theRoses2 — 2 months ago

This short rigged $2.25B Baby Bio is about to Release Phase 3 Registrational Trial results giving Gps the FDA Green Light to a $28B Total Addressable Market.

Do the Math:

Load As many as you can.
Your future self will thank you.

• Gps will Generate Nearly $5B Per YEAR Just for the 12,500 AML CR2/3 Patients
• 12,500 Patients 34/36 Month Median OS
• 3 Year Dosing Regime
• Co Estimated $300K Rev Per patient year 1, $120K Year 2, $80K Y3
• 80% Patient Uptake Rates --- Just shy of $5B in Revenue
• Then ADD in 40,000 AML CR1 Patients Each Year
• 5 year Dosing
• +100,000 AML Patients Currently In Remission right now, who'll benefit from Gps Immunotherapy, right out of the GATE.

Aug 04, 2026 9:57 AM

Here is the CEO explaining there are 10,000 AML CR2 Patients Each Year in just the US/Eu5/Japan

-- this Short Manipulated $2B Baby Bio is about to be Worth EVERY NICKEL of $50B to Big Pharma - the Instant Gps Phase 3 Results are Announced:

• GPs PH3 MOS 34/36 Months / BAT ~ 8 wSerious Toxicity.

86 Days Since the 78th Event / we'd been Seeing an Event Every 22 Days ---
80th EVENT Has Likely Already Happened, Weeks Ago

--- Top Line Phase 3 Results NOW Truly Imminent.\\

https://preview.redd.it/b7o32qvt7nhh1.png?width=1134&format=png&auto=webp&s=283695d9a8fe23c7e26e6a31a76e07bac78d943a

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u/Run4theRoses2 — 2 months ago