Stable on 25mg Prozac for 6 years. Bad flare-up, doctor wants 40mg. Second opinion?
I'm 31M. Had occasional anxiety starting around 2017–2018, followed by a severe anxiety/depression/panic/harm-OCD spiral in 2020.
Started Prozac at 20mg. The initial adjustment was brutal. After 3–4 months, I was improving but not quite myself. My doctor suggested 40mg, but doubling my dose seemed excessive when I just needed a little more help.
I pushed for 25mg (alternating 20/30mg), wanting the lowest effective dose and room to increase later.
It worked! I stayed relatively stable for almost 6 years, with only minor breakthrough anxiety. Glad I advocated for myself.
Fast-forward to Sept 29, 2026: Woke up with intense anxiety, impending doom, panic, and nausea. Felt like my original spiral returning, though not quite as severe. The physical fight-or-flight has eased somewhat, but the underlying anxiety, restlessness, negative thoughts, and rumination remain.
- Oct 4: Doctor immediately recommended 40mg again. I agreed to start at 30mg.
- Oct 10: After a week on 30mg, possibly some minor improvements, but still struggling. She recommends 40mg on Oct 17.
Here's my dilemma:
I genuinely like my family doctor. She's a great GP, but mental health doesn't seem to be her strong suit. She's quick to suggest higher doses or switching medications without fully hearing how debilitating the symptoms and adjustments can be. At my last appointment, I almost felt blamed for my anxiety, like I should just think my way out of it.
Six years ago, she recommended 40mg when 25mg was enough. Maybe she's right now, but I'm worried about increasing too quickly, triggering activation, or taking more than necessary. Having room to increase later also reassures me, even if that's not exactly how antidepressants work.
She's away for three weeks. I'm seeing her covering doctor Oct 21 and considering waiting for that opinion before increasing.
She also suggested temporary Ativan, but I'm hesitant about dependence. A therapist once told me that facing anxiety rather than escaping it helps you overcome it, and that stuck with me. I've been white-knuckling through instead of using rescue medication, which I also felt somewhat blamed for.
My questions:
Has anyone had a severe flare-up after years on an SSRI and stabilized with a smaller increase, or did you need a bigger jump?
Is two weeks on 30mg enough before increasing to 40mg? Would slower titration reduce activation? If tolerable, why not give 30mg 6–8 weeks, or do the benefits of increasing sooner outweigh the risks?
Would a psychiatrist offer more individualized medication guidance than a GP, or just more dismissive pill-pushing?
I'm not against 40mg if I need it. I'm open to whatever helps. I just want to feel confident it's necessary and have someone hear me out, consider my history and concerns, and help me make a plan I trust.
Honestly, I'm scared of repeating what happened six years ago. I just want to feel like myself again.
Any advice or similar experiences would mean a lot.