Palantir Is Building The "Brain of The Firm" Envisioned Half a Century Ago
▲ 37 r/Palantir_Investors+1 crossposts

Palantir Is Building The "Brain of The Firm" Envisioned Half a Century Ago

An organization can sense and act on its own, but it has always had to borrow its reasoning from the humans it employs. Palantir's ontology hands it a living model of itself, AI supplies the capacity to reason over it, and together they might give the enterprise a functional intelligence of its own.

open.substack.com
u/dontkry4me — 10 hours ago
▲ 13 r/OptimistsUnite+1 crossposts

Innovation: America's Perpetual Frontier

At her 250th birthday, America is still opening frontiers. Boosters settle into the arms of launch towers, machines think at scale, and drugs reach targets once thought undruggable. The rational position is an almost delusional optimism about what Americans build next.

open.substack.com
u/dontkry4me — 14 hours ago

Nektar's Rezpegaldesleukin: Aiming To Restore Peripheral Immune Balance

Rezpegaldesleukin selectively expands regulatory T cells to restore peripheral immune balance. Phase 2b trials showed impressive, deepening efficacy in AD and meaningful hair regrowth in AA.

chaotropy.substack.com
u/dontkry4me — 22 days ago

Why Licensing A Dual-Mechanism Anti-IgE Antibody Could Be A Major Opportunity For Cue Biopharma

Cue licensed CUE-221, a dual-mechanism anti-IgE antibody. A controlled Phase 2 in CSU in mainland China is expected to read out in H2 2026, after which Cue plans a global Phase 2b in food allergy.

open.substack.com
u/dontkry4me — 2 months ago

Hemay’s Phase 2 mufemilast data suggest that oral PDE4 inhibition can drive biologic-range remission rates in moderate-to-severe ulcerative colitis. This class-level evidence may partially de-risk Palisade Bio’s PALI-2108.

u/dontkry4me — 2 months ago