u/lexa246

Hi. 3 years ago in November 2023 I suffered a tbi/concussion that produced odds symptoms but basically everything went away after 4 weeks.

2 1/2 years later in April of this year 2026 randomly a lot of these symptoms just came back out of the blue but kind of came in stages.

April 2026- urinary issues no thirst.

May 2026 - no hunger no sign of fullness.

August 2026 - lack of sex drive and cannot fall asleep at all or feel tired. Literally 1 hour sleep maybe max a night. Randomly came previous night was sleeping fine next night nothing working can’t sleep.

I’ve tried reading and scoping the internet to find anything similar but just can’t. Looking for some people that can help guide me.

Also all my hormone in a test that was done in June when the symptoms were active came back all clear and within normal range. Also 3T MRI of the brain and pituitary with contrast came back clean as well.

Looking for help.

---

28M, otherwise healthy, active, live in a hot/humid climate. This has been happening in waves for 3 years and the current episode has me pretty freaked out, so I'm putting it out here to see if anyone has been through anything similar.

**How it started (2023):**
I got a mild concussion playing soccer — a lobbed ball off the top of my head, genuinely nothing dramatic. The next day I started peeing constantly and drinking constantly, like 6 liters in / 6 liters out. Ended up in the hospital. Water deprivation test, electrolytes, brain MRI — all normal. It lasted about 3 weeks and then one morning I woke up and it was just gone. Back to normal.

**Second episode (2024):**
About a year later I lightly bumped my head pulling luggage out of an overhead bin. A few hours later, same thing — constant peeing and thirst. This one lasted ~2 weeks and again resolved overnight. I figured my head was just sensitive and moved on. Totally normal for the next ~18 months — exercising, drinking, everything fine, even bumped my head a few times with no issues.

**This episode (started April 2026) — where it gets strange:**
No head injury this time. I got into bed one night and it was like a switch flipped — instant thirst and peeing. First week was like before (drink a ton, pee a ton, very thirsty).

Then about a week in, overnight, everything flipped at once:
- My urine output crashed — I'd drink 2.5L and only pee ~600ml, dark concentrated urine.
- At the *exact same time*, my sense of thirst vanished completely.

That was ~15 weeks ago and the thirst has never come back. I don't feel thirsty at all, ever. I drink on a schedule out of habit because I know I have to.

**What it's doing now:**
It fluctuates. Some phases I "dump" everything — drink 500ml and pee it all out clear within 30–60 minutes, and if I *don't* drink I barely pee and my urine concentrates normally. Other phases I "clamp" — barely pee for days, very concentrated, clearly retaining water. It swings between these two states. Zero thirst through all of it.

**Every test I've had:**
- Brain/pituitary MRI + contrast: normal except a "partial empty sella" (told it's incidental)
- Full pituitary hormone panel: normal (cortisol, ACTH stim test, thyroid, prolactin, everything)
- Urine osmolality: ~900 mOsm/kg — so my kidneys CAN concentrate
- Serum osmolality: 295, serum sodium: normal every single time
- Full autoimmune/inflammatory workup: clean (CRP, ESR, ANA, complement all normal)
- Kidney function: perfect
- Tumor markers: normal

So structurally everything looks fine. My kidneys and the water hormone (ADH/vasopressin) clearly work — I can concentrate urine when I don't drink. The problem seems to be in how my brain *regulates* when to hold vs. dump water, and the thirst signal is just offline.

The closest thing I've found reading about this is an "adipsic DI" or "reset osmostat" type picture — where the set point for both thirst and the water hormone shifts. But everything I read about that involves a tumor, aneurysm, or brain surgery, and I've had none of that. Just a mild concussion 3 years ago.

**Doctors:** the first endocrinologist told me it was anxiety (it's very much not — you can't fake a urine osmolality). Since then everyone's been stumped. I'm now under a neurologist, keeping a detailed daily diary, and waiting on proper dynamic testing (hypertonic saline + copeptin + a formal thirst measurement).

**What I'm asking:**
Has anyone experienced anything like this? Specifically:
- Recurrent episodes triggered by minor head knocks that fully resolved on their own?
- Completely losing your sense of thirst — and did it ever come back?
- This kind of swinging between retaining water and dumping everything you drink?
- Anything you'd push your doctors to test?

It's so clearly *something*, but nobody can name it and every scan is clean, which is a maddening place to be. Any similar experiences, ideas, or advice would genuinely mean a lot.

**TL;DR:** 3 years of episodes (first two triggered by minor head bumps) where I lose control of water balance — polyuria that flips into water retention. In the latest episode I completely lost my sense of thirst 15 weeks ago and it hasn't returned. All scans, bloods, and hormones normal; kidneys work fine. Looks like a brain osmoregulation / thirst set-point problem but no structural cause found. Anyone been through anything similar?

28M, otherwise healthy, active, live in a hot/humid climate. This has been happening in waves for 3 years and the current episode has me pretty freaked out, so I'm putting it out here to see if anyone has been through anything similar.

**How it started (2023):**
I got a mild concussion playing soccer — a lobbed ball off the top of my head, genuinely nothing dramatic. The next day I started peeing constantly and drinking constantly, like 6 liters in / 6 liters out. Ended up in the hospital. Water deprivation test, electrolytes, brain MRI — all normal. It lasted about 3 weeks and then one morning I woke up and it was just gone. Back to normal.

**Second episode (2024):**
About a year later I lightly bumped my head pulling luggage out of an overhead bin. A few hours later, same thing — constant peeing and thirst. This one lasted ~2 weeks and again resolved overnight. I figured my head was just sensitive and moved on. Totally normal for the next ~18 months — exercising, drinking, everything fine, even bumped my head a few times with no issues.

**This episode (started April 2026) — where it gets strange:**
No head injury this time. I got into bed one night and it was like a switch flipped — instant thirst and peeing. First week was like before (drink a ton, pee a ton, very thirsty).

Then about a week in, overnight, everything flipped at once:
- My urine output crashed — I'd drink 2.5L and only pee ~600ml, dark concentrated urine.
- At the *exact same time*, my sense of thirst vanished completely.

That was ~15 weeks ago and the thirst has never come back. I don't feel thirsty at all, ever. I drink on a schedule out of habit because I know I have to.

**What it's doing now:**
It fluctuates. Some phases I "dump" everything — drink 500ml and pee it all out clear within 30–60 minutes, and if I *don't* drink I barely pee and my urine concentrates normally. Other phases I "clamp" — barely pee for days, very concentrated, clearly retaining water. It swings between these two states. Zero thirst through all of it.

**Every test I've had:**
- Brain/pituitary MRI + contrast: normal except a "partial empty sella" (told it's incidental)
- Full pituitary hormone panel: normal (cortisol, ACTH stim test, thyroid, prolactin, everything)
- Urine osmolality: ~900 mOsm/kg — so my kidneys CAN concentrate
- Serum osmolality: 295, serum sodium: normal every single time
- Full autoimmune/inflammatory workup: clean (CRP, ESR, ANA, complement all normal)
- Kidney function: perfect
- Tumor markers: normal

So structurally everything looks fine. My kidneys and the water hormone (ADH/vasopressin) clearly work — I can concentrate urine when I don't drink. The problem seems to be in how my brain *regulates* when to hold vs. dump water, and the thirst signal is just offline.

The closest thing I've found reading about this is an "adipsic DI" or "reset osmostat" type picture — where the set point for both thirst and the water hormone shifts. But everything I read about that involves a tumor, aneurysm, or brain surgery, and I've had none of that. Just a mild concussion 3 years ago.

**Doctors:** the first endocrinologist told me it was anxiety (it's very much not — you can't fake a urine osmolality). Since then everyone's been stumped. I'm now under a neurologist, keeping a detailed daily diary, and waiting on proper dynamic testing (hypertonic saline + copeptin + a formal thirst measurement).

**What I'm asking:**
Has anyone experienced anything like this? Specifically:
- Recurrent episodes triggered by minor head knocks that fully resolved on their own?
- Completely losing your sense of thirst — and did it ever come back?
- This kind of swinging between retaining water and dumping everything you drink?
- Anything you'd push your doctors to test?

It's so clearly *something*, but nobody can name it and every scan is clean, which is a maddening place to be. Any similar experiences, ideas, or advice would genuinely mean a lot.

**TL;DR:** 3 years of episodes (first two triggered by minor head bumps) where I lose control of water balance — polyuria that flips into water retention. In the latest episode I completely lost my sense of thirst 15 weeks ago and it hasn't returned. All scans, bloods, and hormones normal; kidneys work fine. Looks like a brain osmoregulation / thirst set-point problem but no structural cause found. Anyone been through anything similar?

---

28M, otherwise healthy, active, live in a hot/humid climate. This has been happening in waves for 3 years and the current episode has me pretty freaked out, so I'm putting it out here to see if anyone has been through anything similar.

**How it started (2023):**
I got a mild concussion playing soccer — a lobbed ball off the top of my head, genuinely nothing dramatic. The next day I started peeing constantly and drinking constantly, like 6 liters in / 6 liters out. Ended up in the hospital. Water deprivation test, electrolytes, brain MRI — all normal. It lasted about 3 weeks and then one morning I woke up and it was just gone. Back to normal.

**Second episode (2024):**
About a year later I lightly bumped my head pulling luggage out of an overhead bin. A few hours later, same thing — constant peeing and thirst. This one lasted ~2 weeks and again resolved overnight. I figured my head was just sensitive and moved on. Totally normal for the next ~18 months — exercising, drinking, everything fine, even bumped my head a few times with no issues.

**This episode (started April 2026) — where it gets strange:**
No head injury this time. I got into bed one night and it was like a switch flipped — instant thirst and peeing. First week was like before (drink a ton, pee a ton, very thirsty).

Then about a week in, overnight, everything flipped at once:
- My urine output crashed — I'd drink 2.5L and only pee ~600ml, dark concentrated urine.
- At the *exact same time*, my sense of thirst vanished completely.

That was ~15 weeks ago and the thirst has never come back. I don't feel thirsty at all, ever. I drink on a schedule out of habit because I know I have to.

**What it's doing now:**
It fluctuates. Some phases I "dump" everything — drink 500ml and pee it all out clear within 30–60 minutes, and if I *don't* drink I barely pee and my urine concentrates normally. Other phases I "clamp" — barely pee for days, very concentrated, clearly retaining water. It swings between these two states. Zero thirst through all of it.

**Every test I've had:**
- Brain/pituitary MRI + contrast: normal except a "partial empty sella" (told it's incidental)
- Full pituitary hormone panel: normal (cortisol, ACTH stim test, thyroid, prolactin, everything)
- Urine osmolality: ~900 mOsm/kg — so my kidneys CAN concentrate
- Serum osmolality: 295, serum sodium: normal every single time
- Full autoimmune/inflammatory workup: clean (CRP, ESR, ANA, complement all normal)
- Kidney function: perfect
- Tumor markers: normal

So structurally everything looks fine. My kidneys and the water hormone (ADH/vasopressin) clearly work — I can concentrate urine when I don't drink. The problem seems to be in how my brain *regulates* when to hold vs. dump water, and the thirst signal is just offline.

The closest thing I've found reading about this is an "adipsic DI" or "reset osmostat" type picture — where the set point for both thirst and the water hormone shifts. But everything I read about that involves a tumor, aneurysm, or brain surgery, and I've had none of that. Just a mild concussion 3 years ago.

**Doctors:** the first endocrinologist told me it was anxiety (it's very much not — you can't fake a urine osmolality). Since then everyone's been stumped. I'm now under a neurologist, keeping a detailed daily diary, and waiting on proper dynamic testing (hypertonic saline + copeptin + a formal thirst measurement).

**What I'm asking:**
Has anyone experienced anything like this? Specifically:
- Recurrent episodes triggered by minor head knocks that fully resolved on their own?
- Completely losing your sense of thirst — and did it ever come back?
- This kind of swinging between retaining water and dumping everything you drink?
- Anything you'd push your doctors to test?

It's so clearly *something*, but nobody can name it and every scan is clean, which is a maddening place to be. Any similar experiences, ideas, or advice would genuinely mean a lot.

**TL;DR:** 3 years of episodes (first two triggered by minor head bumps) where I lose control of water balance — polyuria that flips into water retention. In the latest episode I completely lost my sense of thirst 15 weeks ago and it hasn't returned. All scans, bloods, and hormones normal; kidneys work fine. Looks like a brain osmoregulation / thirst set-point problem but no structural cause found. Anyone been through anything similar?

---

28M, otherwise healthy, active, live in a hot/humid climate. This has been happening in waves for 3 years and the current episode has me pretty freaked out, so I'm putting it out here

**How it started (2023):**
I got a mild concussion playing soccer — a lobbed ball off the top of my head, genuinely nothing dramatic. The next day I started peeing constantly and drinking constantly, like 6 liters in / 6 liters out. Ended up in the hospital. Water deprivation test, electrolytes, brain MRI — all normal. It lasted about 3 weeks and then one morning I woke up and it was just gone. Back to normal.

**Second episode (2024):**
About a year later I lightly bumped my head pulling luggage out of an overhead bin. A few hours later, same thing — constant peeing and thirst. This one lasted ~2 weeks and again resolved overnight. I figured my head was just sensitive and moved on. Totally normal for the next ~18 months — exercising, drinking, everything fine, even bumped my head a few times with no issues.

**This episode (started April 2026) — where it gets strange:**
No head injury this time. I got into bed one night and it was like a switch flipped — instant thirst and peeing. First week was like before (drink a ton, pee a ton, very thirsty).

Then about a week in, overnight, everything flipped at once:
- My urine output crashed — I'd drink 2.5L and only pee ~600ml, dark concentrated urine.
- At the *exact same time*, my sense of thirst vanished completely.

That was ~15 weeks ago and the thirst has never come back. I don't feel thirsty at all, ever. I drink on a schedule out of habit because I know I have to.

**What it's doing now:**
It fluctuates. Some phases I "dump" everything — drink 500ml and pee it all out clear within 30–60 minutes, and if I *don't* drink I barely pee and my urine concentrates normally. Other phases I "clamp" — barely pee for days, very concentrated, clearly retaining water. It swings between these two states. Zero thirst through all of it.

**Every test I've had:**
- Brain/pituitary MRI + contrast: normal except a "partial empty sella" (told it's incidental)
- Full pituitary hormone panel: normal (cortisol, ACTH stim test, thyroid, prolactin, everything)
- Urine osmolality: ~900 mOsm/kg — so my kidneys CAN concentrate
- Serum osmolality: 295, serum sodium: normal every single time
- Full autoimmune/inflammatory workup: clean (CRP, ESR, ANA, complement all normal)
- Kidney function: perfect
- Tumor markers: normal

**Doctors:** the first endocrinologist told me it was anxiety (it's very much not — you can't fake a urine osmolality). Since then everyone's been stumped. I'm now under a neurologist, keeping a detailed daily diary, and waiting on proper dynamic testing (hypertonic saline + copeptin + a formal thirst measurement).

**What I'm asking:**
Has anyone experienced anything like this? Specifically:
- Recurrent episodes triggered by minor head knocks that fully resolved on their own?
- Completely losing your sense of thirst — and did it ever come back?
- This kind of swinging between retaining water and dumping everything you drink?
- Anything you'd push your doctors to test?

It's so clearly *something*, but nobody can name it and every scan is clean, which is a strange place to be.

28M, 6+ weeks into something my doctors can’t figure out — anyone been through this?

Hoping someone has been through something similar.

I’m 28, generally healthy. Back in November 2023 I had a minor concussion playing football. A couple days later I started peeing constantly about 6L a day, drinking water nonstop, constant thirst, had a racing heart, body temp fluctuations, brain fog. Lasted 3-4 weeks then went away completely. Did check ups at one point my thyroid tsh was low but went back to normal.

August 2024 I tapped my head on an overhead luggage bin getting off a plane. Few hours later, same thing — peeing 6L more a day and thirst. Lasted 2 weeks, resolved.

Then 19 months of being totally fine. Ran a marathon. Lived normally. Bumped my head a few times during that period and nothing happened.

April 12 this year it came back with no trigger. Hadn’t hit my head in months. Wasn’t sick or stressed. Just started.

But this one is completely different.

First 5 days were like before — excessive thirst, peeing 4-5L a day. Then April 17 it flipped. Output dropped to 400-1200mL despite drinking 2-3L. Concentrated urine. Headaches, dizziness started.

April 27 my thirst just disappeared. Not reduced — gone. Next day my hunger went too. Can’t tell when I’m hungry, can’t tell when I’m full. Three weeks later, still gone.

Then it started flip-flopping. Brief bursts of peeing a lot, then clamping down hard for days. Drink 2L, pee 400mL. Next day pee constantly. No pattern.

I got a full workup at a major hospital. 3T MRI brain and pituitary with contrast — clean except partial empty sella (apparently common, often incidental). Sodium stable at 138-141 throughout. Cortisol stim test normal. All pituitary hormones normal. Kidneys fine. Inflammation markers clean.

Doctors couldn’t find anything. Everything looks normal.

I’m at week 6-7 now. Still no thirst. Still no hunger. Still oscillating between peeing a lot and clamping completely. Sleep is broken. Constant low-level headache. Weak on standing. Brain fog.

My sodium is still fine. Everything keeps testing clean. But I keep flip-flopping and the not-knowing is killing me.

The first two episodes had clear triggers and resolved cleanly. This one has no trigger, keeps evolving, and has lasted 4x longer than my previous ones.

Anyone been through something like this? Episodes that come and go for years then one that’s completely different? Multi-system stuff where thirst, hunger, and sleep all get affected at once? Cant find anything online at all.

Nothing is making sense and I’m worried this time around it’s permanent because no one can explain and no one has ever heard of this. And this episode whatever it is, is so different compared to any of the other episodes. And I only started getting these weird episodes after I hit my head.

28M, 6+ weeks into something my doctors can’t figure out — anyone been through this?

Hoping someone has been through something similar.

I’m 28, generally healthy. Back in November 2023 I had a minor concussion playing football. A couple days later I started peeing constantly about 6L a day, drinking water nonstop, constant thirst, had a racing heart, body temp fluctuations, brain fog. Lasted 3-4 weeks then went away completely. Did check ups at one point my thyroid tsh was low but went back to normal.

August 2024 I tapped my head on an overhead luggage bin getting off a plane. Few hours later, same thing — peeing 6L more a day and thirst. Lasted 2 weeks, resolved.

Then 19 months of being totally fine. Ran a marathon. Lived normally. Bumped my head a few times during that period and nothing happened.

April 12 this year it came back with no trigger. Hadn’t hit my head in months. Wasn’t sick or stressed. Just started.

But this one is completely different.

First 5 days were like before — excessive thirst, peeing 4-5L a day. Then April 17 it flipped. Output dropped to 400-1200mL despite drinking 2-3L. Concentrated urine. Headaches, dizziness started.

April 27 my thirst just disappeared. Not reduced — gone. Next day my hunger went too. Can’t tell when I’m hungry, can’t tell when I’m full. Three weeks later, still gone.

Then it started flip-flopping. Brief bursts of peeing a lot, then clamping down hard for days. Drink 2L, pee 400mL. Next day pee constantly. No pattern.

I got a full workup at a major hospital. 3T MRI brain and pituitary with contrast — clean except partial empty sella (apparently common, often incidental). Sodium stable at 138-141 throughout. Cortisol stim test normal. All pituitary hormones normal. Kidneys fine. Inflammation markers clean.

Doctors couldn’t find anything. Everything looks normal.

I’m at week 6-7 now. Still no thirst. Still no hunger. Still oscillating between peeing a lot and clamping completely. Sleep is broken. Constant low-level headache. Weak on standing. Brain fog.

My sodium is still fine. Everything keeps testing clean. But I keep flip-flopping and the not-knowing is killing me.

The first two episodes had clear triggers and resolved cleanly. This one has no trigger, keeps evolving, and has lasted 4x longer than my previous ones.

Anyone been through something like this? Episodes that come and go for years then one that’s completely different? Multi-system stuff where thirst, hunger, and sleep all get affected at once? Cant find anything online at all.

Nothing is making sense and I’m worried this time around it’s permanent because no one can explain and no one has ever heard of this. And this episode whatever it is, is so different compared to any of the other episodes. And I only started getting these weird episodes after I hit my head.