r/Retatrutide

Retatrutide TRIUMPH Phase 3 Top Line results MEGATHREAD

Retatrutide TRIUMPH Phase 3 Top Line results MEGATHREAD

As I'm sure you all saw the news. Lilly released the top line (so just the 'main data') of TRIUMPH, so to keep it all contained Lets just talk about it all here.

The Data:

https://preview.redd.it/w6a9we34sh2h1.png?width=1021&format=png&auto=webp&s=7ba9d0452c24e58155596b144667e3b4e6757aba

Now now now It looks all great and such, but a few key things to note.

Mostly, these numbers are all based on participants' MAXIMUM TOLERATED DOSE I cannot stress that part enough.

We still don't have the AE (Adverse Effects) data or how many participants ended up with which side effect. That'll most likely come next week (I believe) when they release the FULL report.

https://preview.redd.it/3ov7rjx0vh2h1.png?width=791&format=png&auto=webp&s=af86b95fcee2c97451c1546e7a4089d809c14973

(Yes I used Claude to make a chart w/ Lilly's data cuz Lilly didn't provide one)

But yeah with that said. Discuss.

Also, I won't ask the mods to pin this, as I would save that for when the full report comes out.

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u/EmZephyr — 1 day ago

And here we go. Eli Lilly again.

I am not into Reta, but I was thinking on getting some before Eli Lilly starts controlling the production of Reta.

▲ 0 r/Retatrutide+1 crossposts

Reta experiment going well

Reta is the best thing I ever experimented with. Right now I’m also with Mots-c, slu pp 332, sermorelin and ghk-cu. At this point probably I’ll do a show in July 11.

u/No_Programmer3833 — 1 day ago

april vs may

1.5 weeks on reta currently, pictures r taken month apart ! do u guys see any difference? ~69-70kgs in first pictures to 65.5kg rn

u/Equivalent_Ad_3443 — 1 day ago

April 1 - May 21

30F
SW: 195lbs
CW: 176 lbs
Work out 3-5 days a week
Started at .5mg a week and now at 2mg a week split into 2 doses.

u/tattedbeauty3 — 1 day ago
▲ 10 r/Retatrutide+1 crossposts

Who else is feeling emotionally unattached from material things?

Just finished my 6th week on 2mg..feeling great 😊 I can’t believe that whatever material things I’ve been hoarding meant nothing to me as I was spring cleaning. I was able to declutter all my closets and drawers without looking back and moping about it lol The anhedonia is real 👏

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u/Tiny_Response6181 — 1 day ago

Got the real stuff now or is this something else ?

Got my Reta from a different vendor, initially I was at 4mg and had no issues. I got it from this new vendor and 2.5mg is giving me insomnia, severe thirst.

Is the new stuff real and the old one was fake or what’s going on here ?

Share your thoughts. Thanks.

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u/TittiesAreMyTherapy — 1 day ago

Where to pin when there’s no fat left?

Might be a dumb question, but I’m wondering what the best course of action may be. Perhaps a question for the bodybuilders/super lean individuals.

I’ve reached a point where the last bits of fat that I can pinch feels essentially just “slightly thicker skin”, glute med/adductors and ever so slightly in the lower abs. Dropped 80 lbs in the span of a year, current dose @3mg of RT/week.

My question: what are the best spots for injections when there’s essentially almost no fat left subQ that you can pinch? Does it matter at all as long as I’m going subQ?

I’m asking because every time I pin, the injection leaves a spot under the skin kinda like “trapped liquid” which I’m assuming is due to leanness, and that tends to last for 1-3 days, so I was wondering if there would be better spots I could inj without leaving these “bumps”

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u/Ok-Salamander-7812 — 1 day ago

Lates NY Times Article on Reta

The drug, retatrutide, appears to be the most powerful yet in a wave of injections and pills that have transformed the treatment of obesity — so much so that some participants in other research have said they stopped taking retatrutide because they felt they were losing too much weight.

The results announced by Eli Lilly were from a randomized study of 2,339 patients who were obese or overweight. Those who got the highest dose of the drug had lost 70 pounds on average, or 28 percent of their body weight, after 80 weeks, the company said.

Full article: https://www.nytimes.com/2026/05/21/science/retatrutide-weight-loss-drug.html?smid=nytcore-ios-share

u/Lightlukey — 1 day ago

Bald patch

Just noticed a bald patch in beard , been on Reta for 4 weeks at 2mg pw. Nothing else has changed in my life apart from starting Reta. Any help?

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u/Ok-Ad6649 — 1 day ago

Does anyone have an explanation for this

Whyyyy do so many people I talk to including myself just stop giving a crap when they are on Reta? Like about drinking or any vice even? Just walking around like “idgaf” energy. What is the cause for this

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u/crybabyho3 — 1 day ago
▲ 2 r/Retatrutide+2 crossposts

Reta Titration: does this make sense?

0.25 per week for 4 weeks
0.25 x 0.25 per week for 4 weeks (0.50 split 2x per week)
0.25 x 0.50 per week for 4 weeks
0.50 x 0.50 per week for 4 weeks (I’m here right now)
0.50 x 0.75 per week for 4 weeks
0.75 x 0.75 per week for 4 weeks
0.75 x 1.00 per week for 4 weeks
1.00 x 1.00 per week for 4 weeks (2mg per week)
And then I plan to taper down the same way from 2.mg down to 0.25 per week to a complete stop.

I’ve also been taking tb500 and bpc 150 combo for the last 2 months but will stop it soon because I heard it should not be taken for too long? And I’ve been taking urolithin A and Slu-pp because it is meant to maintain muscle?!

I plan to start NAD+ soon as well.

Does this titration make sense, I’m at 0.50 x 0.50 right now in week 2 and honestly since I started I haven’t felt any major difference - no side effects and I’m not entirely even sure if my hunger is curbed, but it might have just a little bit.

My question is - is anyone else doing this? Does this titration make sense?

I’m trying to lose about 30 -40 lbs which I gained after a back injury because I can’t really do much cardio anymore . I don’t want to take it forever so weaning off is important

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Anecdotal experiences

What’s been your experience so far?

Thought it’d be cool to make a thread where people can just share anecdotal experiences, lessons learned, habits they’ve built, titration schedules, side effects, surprises, mistakes, what worked, what didn’t, etc.

Could be anything:
- how fast/slow you titrated
- appetite changes
- gym/performance effects
- foods you can/can’t tolerate now
- fatigue, sleep, mood
- things you wish you knew earlier
- weird unexpected benefits or downsides
- routines/habits that made things easier

Not really looking for “medical advice” — more just real experiences from people actually going through it so others can learn and compare notes.

Feel free to include:
- current dose
- how long you’ve been on
- weight loss/body comp changes
- biggest lesson so far

Interested to hear everyone’s experiences.

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u/Numerous-Store8598 — 1 day ago

Reached the final notch on my belt.

Hello all, first time posting here but I started taking retatrutide about 1.8 months ago and have been on a steady weight loss since the start, losing almost a total of 12kg.

I have a belt that I have been using this whole time. When I started my weight loss program I used it mainly for aesthetics and I would use the first notch on the belt, maaaayyybe the second but it would feel extremely tight on my waist. Today, I just realized that I am on the last notch and my pants are still loose, guess it is time to drill some new notches.

For me this is particularly interesting since I do notice myself slightly thinner on the mirror (specially on the face) and the scale, but since the weight loss was mainly volumetric and uniform on my body I did not realize the profund effects it has had on me until I noted the belt.

I know this is not particularly spectacular compared to some other posts here, just something I found interesting. Thanks for the read!

PS: I only take reta and go to the gym about 5-6x a week for hypertrophy training and some cardio. Also do sauna about 2-3 times a week if I can. Supplementing my food with creatine and protein shakes :)

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u/OPedrocasMamocas — 1 day ago

week 1 oon Reda, my pros and concerns so far. starting dose, .75mg.

I started Reta last friday. I started with .75mg and had to meals that day one in the morning and one in the evening. On sat, i ended up so sick and i had to be at work that day. had a pounding headake and felt like i couldnt digest the food from the day before.

At the same time, I was so tired and felt like the ultimate stomach virus was killing me.  After finally throwing up, I felt a bit better.  After working an 8 hour shift I went home and straight to bed.  Next day felt a bit better.  So far its day 5 and I’ve been eating one meal a day.  I plan on lowering this week’s dose to .50 and seeing what happens.  Another thing I noticed is that it’s given me incredible erections, my wifes loving it.  After overcoming the initial first 2 days, it’s been pretty smooth.  Another thing that makes it bad is the constant heartburn.  I’m taking heartburn meds, hopefully this helps.  My Doc said keep doses low, this actually works better on low doses.  For anyone starting out, do it when you have a few days off because the initial reactions are unpredictable.  If anyone has any suggestions or knows what would work great for the heartburn please let me know.  Will keep updating my experience.

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u/SL2999 — 1 day ago

Any advice?

Dropped from 355 to now 226 using Reta and counting calories. Gym 4x a week. Been almost a year next week. My goal has always been 200. Do you all think that’s low enough to cut away my extra fat? What fat % do you think I’d be at 200?

u/Critical_Text_3074 — 1 day ago

A known vendor gave me something else

And they stopped responding to me because they said "because it has a blue cap, it must be reta." 2 months ago I ordered R10 and have been using it weekly. Im up to 8mg on my 9th week and ive never felt any affects what so ever. Im still the same weight, I workout 3-4 times a week, and nothing. Today I decided to lookup my batch number and multiple sites report it to being TB 500. I told the vendor this and they stopped responding to me after saying the blue cap thing. And how they made an announcement a few months ago saying even though the batch numbers may be wrong, if you got the blue cap its reta.

Do I send a vial to Janoshik and then tell them? To try to get reimbursed? They are well known too.

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u/Kurrrrrl — 1 day ago

Sulfur burps are murder right now

31 year old female. 275 pounds, 46% BF. Started Reta on May 18th. Pinned 2mg. Started eating high fiber and protein about a week ago to adjust to nutrition modifications and started exercising about 3 weeks ago. I had no issues Monday or Tuesday. But all of a sudden I’ve been attacked with sulfur burps. It’s the only issue I’ve encountered so far. I’m thinking now I should have started with a lower dose. I based the amount on the trial protocol. I ordered some papaya enzymes to help with digestion and have been drinking peppermint tea all night. Send help.

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u/gigglesandbegonias — 1 day ago