Interesting.
https://gizmodo.com/an-exercise-pill-just-cleared-its-first-human-test-2000800380
Would you take this?
One of many next-gen obesity treatments currently going through the system.
Hi everyone,
I’ve been on 2.5mg for about a year but planned to move up to 5mg due to less of an effect.
This coincided with a 4 week break due to travelling. When I spoke to the pharmacist, they said it was fine to just plough on with the 5mg after the break, as guidelines are only to reduce the dose if you’ve had a break of 6+ weeks.
I trusted this answer and have just done my first 5mg injection.
However now I’m massively panicking that I’ve been ill advised! I made the mistake of googling AFTER doing the jab and everything online says contrary to this advice I was given….
Has anyone done this before and been ok? I know I’m probably in for a rough few days. But do I need to be concerned about my safety/more serious concerns?
Please help reassure a very anxious person over here 😭
Pen Teardown.
Pen Teardown.
Pen teardown.
As an engineer I like to know how stuff works, so the pens intrigued me.
So I’ve taken 5 apart to see, and they are quite clever!
What is clear is they cannot and do not ‘count clicks’.
Pic 1 is all the parts. As suspected there is a glass vial inside the main barrel of the pen.
Pics 2 and 3 are like a double slip clutch mechanism and this is how the pen stops turning when the maximum deflection or travel of the plunger is reached.
The 2 black bits are the same, even though the one inside the dose twister looks different in the picture.
They slot together when this mechanism is all together as in pic 6.
If you look at pic 4 you can see the threaded plunger rod and the squared off bit at the end. This same squared off bit is also present at the other end of the rod.
When you turn the dose twister the 2 black slip clutches engage with each other in the white plastic part inside the main body of the pen handle and turn around the plunger rod which is held firm by a locking system in the main body of the pen that I haven’t got to yet. The black half of the clutch part in the twister turns as you twist
When you the press the purple nob as you inject, the top part of the clutch locks so it doesn’t turn, this then locks the lower part which presses the rod down into the pen.
In pic 4 you can see the threaded plunger rod with the squared off ends. As you use the pen, once you twist it up to the squared bit it can’t move any further unless forced.
This is what locks the pen.
You can see in pic 5 what happens when you force it past the lock. A bit breaks off.
This means we were able to advance the twister further up the rod and get the extra travel on the plunger required to get the extra dose. But this was in no way measured or accurate. Just that the difference wasn’t really an issue.
The new pens are exactly the same with the simple addition of the spacer as seen in pic 7. You can just see that this spacer is 1 dose in size, thereby extending the effective travel of the plunger and eliminating the extra dose.
And that’s it. Very simple yet clever and accurate. Got hold of a Lilly insulin pen and took that apart as well and they are the same with the only difference being the plunger rod is black and longer so it goes all the way to the end of the vial.
:-)
Hi. I have 2 spent pens with a bit left in each. One is 8 weeks since opening & one is 4 weeks since opening. Is it ok to use what's left as it looks like 2 doses in them & seems a waste of money?
I am on my 2nd pen of 7.5mg and have one dose left to take next Saturday. I didn’t have much side effects when I was on the first pen but seemed to have developed a sorta nausea where it makes me gag but not to the point of vomiting. (as someone with a bit of a sick phobia you can understand this gives me a lil fear)
I track my weight on a spreadsheet just so I can pivot and see how much weight I’ve lost on each strength and currently 5mg which I also took for 2 pens is way ahead of 7.5mg. Wondering if it is worth dropping back down to 5mg for a month or 2 and then increasing if needing - saves a little ££ too
Has anyone done/ experienced this ?
Hi, I started mounjaro 4 months ago at 15 stone 2 lbs, and now weight 11 stone 7 lbs. I am now considered normal weight, which is great. My issue is, when do I stop?? My head tells me to keep going, to go until I can see abs, but I don’t want to swing so far the other way I look too skinny!!
What weight is a perfectly fine weight to stop mounjaro at for a 5 foot 7 man?
Female / age 69 / living in the UK
This morning's cooler weather was ideal to get my speeds up 🚶🏾♀️🙂
Hi, I am very happy with the service from my current provider but the price seems to be up to £50 a month more expensive than others. This is a pretty significant difference and is making me genuinely think of switching. Have you switched, was it easy, any tips or regrets?
Currently on a 5mg dose, asked my provider re buying a 15mg pen and counting clicks, no response despite them having a presence here and answering and interacting on other posts….interesting!
Any suggestions or recommendations welcome. Thanks.
I have lipedema which has worsened now I'm 7 months postpartum, the only reason I developed an ED in the first place was that I couldn't understand why my legs looked the way they did. It's affecting my life so much, my mobility, my mental health.
I am 100% recovered and have been for a REALLY long time. Does anyone know any pharmacies that won't just reject me? Feeling really disheartened 😢
Hi all, I am pondering trying the jabs, Iv put on 2.5 stone and it is getting me down real bad. I have such food noise it’s terrible. Is there any providers that would prescribe at this BMI other than MedExpress they seem to get bad reviews ?
My first pen without the golden dose. Gutted honestly. I cannot believe how much the price has gone up since I started but I tried to go off and gained. Absolutely gutted.
Has anybody tried FyboCalm for persistent diarrhoea, if so did it help?
Hello, I’ve had this issue with my past three pens. I have my first three doses fine, but the fourth dose on each does not work. The pen stops clicking halfway to one and jams. I am priming correctly, and I track my doses. I’m genuinely confused. I follow instructions exactly. I switched from Asda online doctor because of this issue, but I’m having the same problem with my first pen from Juniper. They’re stored correctly in the fridge and i can’t think of any reason why this is happening. Has anyone else had this issue?
Edit: when priming I do one click, and push just enough to see a drop of medicine. I track my doses and injection sites, so I’m not forgetting a dose. I also took my first pen to a pharmacist, who confirmed it was faulty.
After the issues of the last few times, I started a new 12.5mg pen. 1st injection just done.
Let's see what happens. I hope after spending a few weeks back to 10mg, my tolerance of 12.5 is better. Last time my appetite suppression was excessive and I was worried about not eating and even drinking water was less than my usual.
I know that's great for losing weight rapidly but I'm more interested in staying healthy while losing weight! I still need to be able to eat nutrinionally dense foods and drink my water without having to think twice about it.
My 6month review is coming up and I'm nervous about that too. I need to keep going as I'm nowhere near where I need to be weight-wise.
I will use this thread over the week as I journal the effects of 12.5mg on me this time around. Hope it might be useful to others.
Love.
Anyone seen and tried this? 🧐