r/pregabalin

Lyrica - Emotional and Mental effect

Hi everyone! Ive recently been diagnosed with Grade 1 Spondylolisthesis L5-S1 with a pars defect. It hasn’t been an easy diagnosis and I’ve had to change many things in life in a span of 1 month since diagnosis.

I’m currently on 75mg and I feel better on my nerves and pain in general, so physically I am coping better. But I am beginning to notice (and people around me) that I am noticeably more quick tempered. While I feel it’s justified, because hey I’m pretty reasonable about it but apparently it isn’t. Am i just more expressive with my condition giving me some mental freedom or is this the medication at work? Anyone had such an experience?

Also, i have never had suicidal thoughts or even depressing thoughts. In general, i have been a motivated individual all along so it’s really surprising. But im unsure if this is age thing, the spondy, or medication or really a combination? I couldn’t snap out of it and certain times.

I’m just hoping to hear if anyone had the same experience or feelings on Lyrica and specifically if they get better over time as your body adjust to the medication? I don’t want to stop because it improves my physical condition which greatly helps.

Also, does increasing dose scale with feeling better or is there a point where it’s just pointless to increase + how it messes with the mental state.

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u/Personal_Number4789 — 1 day ago

Muscle twitches cause by pregabalin?

So ive been taking 150mg twice a day. Ive recently noticed I had been taking a higher dosage around 300mg , because the 50 mg and 150 difference is only marked by a black line in the pill.

So now ive noticed and have reduced my dosage . I didnt thinkbid b much of it. Ive taken higher dosages before without any disturbances.

Would that drop from a higher dosage (for around aweek) cause muscle twitches?

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u/lacedxannies — 1 day ago

Do you look younger or older on pregabalin?

So i've seen tons of discussions about adhd stimulants that they age people's faces long term or that opioids make people look younger. No idea if its true or not and why if yes but just wondering how do you feel on pregabalin long term in this sense? Do you look your age or older or younger? do other people comment your looks?

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u/MisaVelvet — 2 days ago

Got my hands on some expired pregabalin…

As the title says, I got some 75mg pregabalin which has expired. I’ve never done it before. Any recommendations on starting dose and whether anything changes from them being expired?

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u/Any_Leg4807 — 2 days ago

How bad did i mess up

I took 30mg diazepam two days in a row without tolerance, the day after i proceeded to take 600mg pregabalin. Almost immediately after taking the pregabalin i fell asleep for 7 hours. Woke up disoriented with a headache. Could the valium from the previous days have caused a significant amount of respiratory depression?

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u/Old-Personality-5246 — 4 days ago

Pregabalin vs Guanfacine

Currently on Guanfacine. Has anyone here taken Guanfacine in the past then switched to pregabalin, or in the reverse?

Curious of your experiences and how they differ from Guanfacine.

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u/intepid-discovery — 5 days ago

Took 400mg on accident thought it was 100mg a piece and 200mg total. Afraid.

Am I overdosing? I took 30mg hydrocodone earlier with .5g of phenibut. I have a high tolerance to hydros. That was like 7-8 hours ago now. Took 400mg lyrica on accident about an hour ago. Help please.

Edit: thank you guys for the responses. You rock.

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u/No-Pilot-1252 — 6 days ago

Caffeine and Lyrica

I just wanted to write about a couple of positives of pregabalin for me, after being on it now for a couple of months nonstop.

So i used to be super sensitive to caffeine, it would make me jittery and nervous and generally just feel ill. Now on pregabalin and I can drink as many cups as i want with zero jittery effects! i am so happy because I love coffee! And because pregabalin makes me sleep like a baby, even drinking coffee in the afternoon doesn’t affect my sleep. Does anyone else notice this?

Another positive is that even tho my work is super hectic and stressful at the moment, I just feel really chill about it. I am usually the type or person that gets stressed easily and now I don’t get that kind of anxious feeling. it’s super weird but also amazing and also helpful at this moment in my life, especially as I am also waiting for a major surgery and I think I would be super stressed about it, if pregabalin didn’t calm my nerves.

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u/Exotiki — 6 days ago

Lithium and Pregabalin

Hey all,

I recently got prescribed 300mg of Lithium XR per day on top of my 200mg of lamotrigine XR. I'm probably going to increase the lithium after a week or two at this dosage. I take Pregabalin as needed for anxiety usually in the 300-400mg range twice a week-ish on average (if I had to approximate). I don't tend to have anxiolytic effects until 250/300mg and I have a slight tolerance so sometimes I'll take 400mg instead of 300mg if I've taken it within 2-3 days.

My question is: what is everyone's experience taking pregabalin and lithium? Did you notice any changes at all? Did it alter any effects or potentiate? I've seen mixed things online and my psych said everyone is different (obviously dude haha). I'm just trying to gather a little more info.

I'll try it out sooner at a lower dosage like 100-200mg to see how I respond. I'm hoping it will still be effective, but if not, I'll have to try something else.

Thanks!

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u/Decent_Confession119 — 5 days ago

Is this potentially a side effect?

So pregabalin has been life changing for nerve pain relief from my spinal stenosis. I was wondering though, i am a woman in my 20s with autism and my wife has lately been noticing that my face doesn’t always match my mood lately and has been asking if I’m okay a lot more. Basically I feel like masking has been harder and I’m just wondering if anyone else has experienced this. It’s not really something i mind, just something i’m curious about.

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u/No-Ad-9873 — 6 days ago

Does Pregabalin have antidepressant effects?

I took Escitalopram 20mg for a long time. Despite of that, I still had many depressive/intrusive thoughts.

Now, I am on Pregabalin 300mg and all my depressive/intrusive thoughts are gone. It's as if my mind is blank. i don't know if this is emotional blunting, but it feels actually good! It's as if this inner "narrating voice" some people is gone, but it feels actually normal, similarly to how people describe never having an inner voice to begin with.

Anyone having a similar experience on Pregabalin?

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u/preabert — 9 days ago

Accidentally took 150mg Lyrica instead of 75mg while on 50mg Zoloft. Risk of serotonin syndrome?

Hi everyone.

I take 50mg Zoloft (sertraline) daily and 75mg Lyrica (pregabalin) twice a day, morning and evening.

Tonight I accidentally took 150mg of Lyrica instead of my usual 75mg evening dose.

Now I’m anxious about serotonin syndrome or other dangerous interactions.

Has anyone experienced something similar?

Thanks

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u/shikary52 — 9 days ago

Pregablin for anxiety/agoraphobia

So i have GAD and moderate agoraphobia, I was wondering if a 75mg cap of this stuff will work to calm me down? I keep pacing around the house and feel extremely on edge for some reason

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u/PureEnergeticLife — 9 days ago

Pregabalim and cognitive effects

I have a shoulder problem; I’m in a lot of pain. I wake up at night in pain, and sometimes I feel like crying. I can’t stand still in one place because of the pain, and there are days when I feel like I’m going to go crazy... I’m only 24 years old....

I’m studying for the national exams to get into college, and I need 100% of my brainpower available. I’m afraid of cognitive decline, and that it will interfere with my studies (the pain alone isn’t enough). The doctor prescribed me 75 mg at night. Right now I don’t take any pain medication, just alprazolam about 2 or 3 times a week, as a last resort, when I really can’t take it anymore.

I use vortioxetine.

What do you think? It’s hard to deal with all of this: the pressure of taking a difficult exam, learning difficult things, feeling a lot of pain, working....

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u/metaidependencia — 7 days ago

25mg for nerve pain?

My pain specialist just prescribed 25mg once per day for pain and has given me no titration schedule or anything. does that mean I need to go through my GP or will they refuse to manage it since the pain specialist is the one that prescribed it

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u/Recoveryxoxo — 9 days ago

Has anyone been prescribed liquid pregabalin before? In the UK specifically, not elsewhere

I'm having trouble coming off pregabalin (I already came down from 150mg to 50mg,in 25mg drops every month, but I'm finding this last 50mg really difficult for some reason), and asked the GP if there were a more gradual way of reducing it, he claimed there are only the 25mg tablets, but I can see the NHS website gives advice about how to take liquid pregabalin, so I feel like he's just fobbing me off...

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u/Inevitable-Height851 — 10 days ago