u/Puzzleheaded_Bag7816

I started taking Wellbutrin 150mg xl + buspar 7.5mg for four weeks, starting May 15th. While the medication slightly helped their motivation to work, it also caused brain fog and fatigue. I know Wellbutrin causes these side effects because they have taken it in the past; historically, when I stop the medication, the brain fog and fatigue go away, but the depression comes back. After the four weeks of taking Wellbutrin, the I underwent a 5-day accelerated TMS treatment(June 8th - June 12th) at cognitiveFX, remaining on the medication the entire time. The day after TMS ended (Saturday, June 13th), I stopped taking the Wellbutrin 150mg xl + Buspar 7.5mg. From the following Sunday through Thursday, I lacked motivation but completely stopped experiencing the brain fog, just as I expected. However, starting the Friday after treatment concluded (Friday, June 19th which would be exactly 1 week), I suddenly began experiencing horrible brain fog again. This time, it was so severe that it became hard to understand simple sentences and follow simple logical solutions and because of this my mood has completly dipped and I felt SI. It's even hard to try to keep up with watching movies and TV now because I feel like I need more time to process everything even though a normal person would process it right away.

Please give me advice because I am quite scared now. I don't know if this is a TMS dip or what. If you are wondering about me I am 22 years old and have tried multiple meds(failed them) in the past and that's why I even considered TMS.

I started taking Wellbutrin 150mg xl + buspar 7.5mg for four weeks, starting May 15th. While the medication slightly helped their motivation to work, it also caused brain fog and fatigue. I know Wellbutrin causes these side effects because they have taken it in the past; historically, when I stop the medication, the brain fog and fatigue go away, but the depression comes back. After the four weeks of taking Wellbutrin, the I underwent a 5-day accelerated TMS treatment(June 8th - June 12th) at cognitiveFX, remaining on the medication the entire time. The day after TMS ended (Saturday, June 13th), I stopped taking the Wellbutrin 150mg xl + Buspar 7.5mg. From the following Sunday through Thursday, I lacked motivation but completely stopped experiencing the brain fog, just as I expected. However, starting the Friday after treatment concluded (Friday, June 19th which would be exactly 1 week), I suddenly began experiencing horrible brain fog again. This time, it was so severe that it became hard to understand simple sentences and follow simple logical solutions and because of this my mood has completly dipped and I felt SI. It's even hard to try to keep up with watching movies and TV now because I feel like I need more time to process everything even though a normal person would process it right away.

Please give me advice because I am quite scared now. I don't know if this is a TMS dip or what. If you are wondering about me I am 22 years old and have tried multiple meds(failed them) in the past and that's why I even considered TMS.

I started taking Wellbutrin 150mg xl + buspar 7.5mg for four weeks, starting May 15th. While the medication slightly helped their motivation to work, it also caused brain fog and fatigue. I know Wellbutrin causes these side effects because they have taken it in the past; historically, when I stop the medication, the brain fog and fatigue go away, but the depression comes back. After the four weeks of taking Wellbutrin, the I underwent a 5-day accelerated TMS treatment(June 8th - June 12th) at cognitiveFX, remaining on the medication the entire time. The day after TMS ended (Saturday, June 13th), I stopped taking the Wellbutrin 150mg xl + Buspar 7.5mg. From the following Sunday through Thursday, I lacked motivation but completely stopped experiencing the brain fog, just as I expected. However, starting the Friday after treatment concluded (Friday, June 19th which would be exactly 1 week), I suddenly began experiencing horrible brain fog again. This time, it was so severe that it became hard to understand simple sentences and follow simple logical solutions and because of this my mood has completly dipped and I felt SI. It's even hard to try to keep up with watching movies and TV now because I feel like I need more time to process everything even though a normal person would process it right away.

Please give me advice because I am quite scared now. I don't know if this is a TMS dip or what. If you are wondering about me I am 22 years old and have tried multiple meds(failed them) in the past and that's why I even considered TMS.

I started taking Wellbutrin 150mg xl + buspar 7.5mg for four weeks, starting May 15th. While the medication slightly helped their motivation to work, it also caused brain fog and fatigue. I know Wellbutrin causes these side effects because they have taken it in the past; historically, when I stop the medication, the brain fog and fatigue go away, but the depression comes back. After the four weeks of taking Wellbutrin, the I underwent a 5-day accelerated TMS treatment(June 8th - June 12th) at cognitiveFX, remaining on the medication the entire time. The day after TMS ended (Saturday, June 13th), I stopped taking the Wellbutrin 150mg xl + Buspar 7.5mg. From the following Sunday through Thursday, I lacked motivation but completely stopped experiencing the brain fog, just as I expected. However, starting the Friday after treatment concluded (Friday, June 19th which would be exactly 1 week), I suddenly began experiencing horrible brain fog again. This time, it was so severe that it became hard to understand simple sentences and follow simple logical solutions and because of this my mood has completly dipped and I felt SI. It's even hard to try to keep up with watching movies and TV now because I feel like I need more time to process everything even though a normal person would process it right away.

Please give me advice because I am quite scared now. I don't know if this is a TMS dip or what. If you are wondering about me I am 22 years old and have tried multiple meds(failed them) in the past and that's why I even considered TMS.

I started taking Wellbutrin 150mg xl + buspar 7.5mg for four weeks, starting May 15th. While the medication slightly helped their motivation to work, it also caused brain fog and fatigue. I know Wellbutrin causes these side effects because they have taken it in the past; historically, when I stop the medication, the brain fog and fatigue go away, but the depression comes back. After the four weeks of taking Wellbutrin, the I underwent a 5-day accelerated TMS treatment(June 8th - June 12th) at cognitiveFX, remaining on the medication the entire time. The day after TMS ended (Saturday, June 13th), I stopped taking the Wellbutrin 150mg xl + Buspar 7.5mg. From the following Sunday through Thursday, I lacked motivation but completely stopped experiencing the brain fog, just as I expected. However, starting the Friday after treatment concluded (Friday, June 19th which would be exactly 1 week), I suddenly began experiencing horrible brain fog again. This time, it was so severe that it became hard to understand simple sentences and follow simple logical solutions and because of this my mood has completly dipped and I felt SI. It's even hard to try to keep up with watching movies and TV now because I feel like I need more time to process everything even though a normal person would process it right away.

Please give me advice because I am quite scared now. I don't know if this is a TMS dip or what. If you are wondering about me I am 22 years old and have tried multiple meds(failed them) in the past and that's why I even considered TMS.

I made a post a while back about my TRD and MAOIs seemed to be an option my mostly anhedonic depression. I started 20mg of Parnate and after 10 days of taking it. I wanted to share my experience. In the morning when I take it I am okay. I have very little motivation but still okay. If I have it with affiene I feel great especiallly with a workout but later in the evening the depression hits even harder like I do not want to leave my bed and become suicidal. Like to point where I literally laid on my carpet and even accepted my fate that I am perhaps not meant for this life any longer. I told my doctor this and he said to stop the medication. I have tried so many other meds in the past and Parnate I guess didn't work. I was wondering if anybody else has had a simmilar experience and wanted to know what they did to resolve the issue.

Past medicine trials summary

Medication Category	Agents Tried	Clinical Response
SSRIs + Wellbutrin	Lexapro, Zoloft, Celexa, Prozac	Partial mood improvement, but consistently caused significant apathy, fatigue, and brain fog.
SNRIs + Wellbutrin	Duloxetine (Cymbalta), Effexor	Duloxetine + Wellbutrin was the most effective combo for mood, but brain fog/fatigue persisted. Same idea with Effexor
Wellbutrin Monotherapy	100mg SR or 150mg XL	Caused insane amounts of anxiety and made me slightly suicidal. Either one of the doses did this
Buspar + Wellbutrin	150mg XL + 7.5mg Buspar	Felt motivated to do work but brain fog/fatigue persists and at times apathy
TCAs	Desipramine	Increased baseline motivation, but resulted in a "cloudy" sensation and reduced mental capacity to ~65%.
Atypical Antipsychotics	Abilify (5mg)	Trialed as monotherapy; produced negligible results compared to being unmedicated.
Stimulants	Vyvanse (40mg)	Current Treatment. Provides 5–6 hours of efficacy for TRD symptoms but requires caffeine to sustain. Medication holidays result in severe crashes. Felt more motivated on Wellbutrin augmentations
MAOI	Tranylcypromine(20mg)	Very little motivation on it(I realize it was a low dose). However, it increased me Suicidal twice within a 10 day span during evening time. The evening where I didn't feel suicidal, I felt even more depressed and did not want to leave my bed.

I made a post a while back about my TRD and MAOIs seemed to be an option my mostly anhedonic depression. I started 20mg of Parnate and after 10 days of taking it. I wanted to share my experience. In the morning when I take it I am okay. I have very little motivation but still okay. If I have it with affiene I feel great especiallly with a workout but later in the evening the depression hits even harder like I do not want to leave my bed and become suicidal. Like to point where I literally laid on my carpet and even accepted my fate that I am perhaps not meant for this life any longer. I told my doctor this and he said to stop the medication. I have tried so many other meds in the past and Parnate I guess didn't work. I was wondering if anybody else has had a simmilar experience and wanted to know what they did to resolve the issue.

Past medicine trials summary

Medication Category	Agents Tried	Clinical Response
SSRIs + Wellbutrin	Lexapro, Zoloft, Celexa, Prozac	Partial mood improvement, but consistently caused significant apathy, fatigue, and brain fog.
SNRIs + Wellbutrin	Duloxetine (Cymbalta), Effexor	Duloxetine + Wellbutrin was the most effective combo for mood, but brain fog/fatigue persisted. Same idea with Effexor
Wellbutrin Monotherapy	100mg SR or 150mg XL	Caused insane amounts of anxiety and made me slightly suicidal. Either one of the doses did this
Buspar + Wellbutrin	150mg XL + 7.5mg Buspar	Felt motivated to do work but brain fog/fatigue persists and at times apathy
TCAs	Desipramine	Increased baseline motivation, but resulted in a "cloudy" sensation and reduced mental capacity to ~65%.
Atypical Antipsychotics	Abilify (5mg)	Trialed as monotherapy; produced negligible results compared to being unmedicated.
Stimulants	Vyvanse (40mg)	Current Treatment. Provides 5–6 hours of efficacy for TRD symptoms but requires caffeine to sustain. Medication holidays result in severe crashes. Felt more motivated on Wellbutrin augmentations
MAOI	Tranylcypromine(20mg)	Very little motivation on it(I realize it was a low dose). However, it increased me Suicidal twice within a 10 day span during evening time. The evening where I didn't feel suicidal, I felt even more depressed and did not want to leave my bed.

I made a post a while back about my TRD and MAOIs seemed to be an option my mostly anhedonic depression. I started 20mg of Parnate and after 10 days of taking it. I wanted to share my experience. In the morning when I take it I am okay. I have very little motivation but still okay. If I have it with affiene I feel great especiallly with a workout but later in the evening the depression hits even harder like I do not want to leave my bed and become suicidal. Like to point where I literally laid on my carpet and even accepted my fate that I am perhaps not meant for this life any longer. I told my doctor this and he said to stop the medication. I have tried so many other meds in the past and Parnate I guess didn't work. I was wondering if anybody else has had a simmilar experience and wanted to know what they did to resolve the issue.

Past medicine trials summary

Medication Category	Agents Tried	Clinical Response
SSRIs + Wellbutrin	Lexapro, Zoloft, Celexa, Prozac	Partial mood improvement, but consistently caused significant apathy, fatigue, and brain fog.
SNRIs + Wellbutrin	Duloxetine (Cymbalta), Effexor	Duloxetine + Wellbutrin was the most effective combo for mood, but brain fog/fatigue persisted. Same idea with Effexor
Wellbutrin Monotherapy	100mg SR or 150mg XL	Caused insane amounts of anxiety and made me slightly suicidal. Either one of the doses did this
Buspar + Wellbutrin	150mg XL + 7.5mg Buspar	Felt motivated to do work but brain fog/fatigue persists and at times apathy
TCAs	Desipramine	Increased baseline motivation, but resulted in a "cloudy" sensation and reduced mental capacity to ~65%.
Atypical Antipsychotics	Abilify (5mg)	Trialed as monotherapy; produced negligible results compared to being unmedicated.
Stimulants	Vyvanse (40mg)	Current Treatment. Provides 5–6 hours of efficacy for TRD symptoms but requires caffeine to sustain. Medication holidays result in severe crashes. Felt more motivated on Wellbutrin augmentations
MAOI	Tranylcypromine(20mg)	Very little motivation on it(I realize it was a low dose). However, it increased me Suicidal twice within a 10 day span during evening time. The evening where I didn't feel suicidal, I felt even more depressed and did not want to leave my bed.

I made a post a while back about my TRD and MAOIs seemed to be an option my mostly anhedonic depression. I started 20mg of Parnate and after 10 days of taking it. I wanted to share my experience. In the morning when I take it I am okay. I have very little motivation but still okay. If I have it with affiene I feel great especiallly with a workout but later in the evening the depression hits even harder like I do not want to leave my bed and become suicidal. Like to point where I literally laid on my carpet and even accepted my fate that I am perhaps not meant for this life any longer. I told my doctor this and he said to stop the medication. I have tried so many other meds in the past and Parnate I guess didn't work. I was wondering if anybody else has had a simmilar experience and wanted to know what they did to resolve the issue.