▲ 11 r/PMDD

6 Years on Lupron for PMDD: What I Learned About Fertility and Physical Health

I finally got answers from a fertility specialist about what being on long-term Lupron Depot means for my fertility and physical health, and I wanted to share because there is so little information out there about this.

Lupron suppresses my LH and FSH, which is why I don’t get a period or ovulate normally. My body still recruits eggs, but because that process is suppressed, they don’t continue through normal ovulation.

The biggest news for me: when I’m ready to have a baby, I don’t have to come off Lupron first.

The fertility clinic can use fertility medications to stimulate and mature my eggs while controlling exactly when everything happens. In my case, the reason for using fertility medications isn’t simply because I’ve been on Lupron Depot. It’s so the clinic can plan the process down to the exact day and prevent me from going through a normal luteal phase. We already know that the luteal phase is when PMDD symptoms occur, so the goal is to keep that hormonal process controlled rather than allowing my body to ovulate and enter a luteal phase naturally.

They’ll retrieve the eggs before ovulation, fertilize them through IVF, and transfer an embryo back into my uterus at the appropriate time. Once I’m pregnant, I won’t need Lupron during the pregnancy because there is no Luteal phase that I need to avoid every month.

I’ve been on Lupron for 6 years, and during that entire time my only add-back has been Norlutate (norethindrone). I haven’t been able to tolerate estrogen add-back.

Despite those 6 years without estrogen add-back, my internal ultrasounds have shown no signs of damage to my ovaries or uterine lining, and my bone-density scans have also shown no evidence of bone-density damage.

I was also told that I can safely remain on Lupron Depot long-term, once my fertility specialist finds an estrogen add-back that I can tolerate.

I paid $125 for a blood test to assess my ovarian reserve, and my result was 21! The rest of my fertility care will be covered through OHIP in Ontario, Canada.

After 6 years on Lupron, I was also told there is no reason to believe that Lupron has damaged the quality of my eggs.

Dr. Robert Casper, the Director of TRIO Fertility in Toronto, is going to create a long-term Lupron plan and a future fertility plan for me before he retires this fall. When I am ready, I will take the fertility plan to the clinic of my choice and they will implement it. My OBGYN will be responsible for the ongoing Lupron treatment and the process of finding an appropriate Estrogen add-back.

I am SO relieved. One of my biggest fears about needing Lupron long-term was what it could mean for having biological children and my long term physical health.

I also wanted to post this because I know how difficult it was for me to find information about long-term Lupron use, PMDD, and future fertility. If someone searches Reddit for the same answers months or years from now, hopefully my experience can at least give them some questions to bring to their own doctors.

Obviously this is my individual treatment plan and what my fertility specialist told me about my situation. Not medical advice or a guarantee that the same approach applies to everyone using Lupron.

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u/TheGentleComeback — 5 days ago

Ontario, what are we doing?

How are people getting this covered in Ontario? My Sunlife insurance won't cover it, ODSP won't cover it, and EAP won't cover it.
I have diagnosed PCOS and obesity.

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u/TheGentleComeback — 20 days ago

Train & Barenaked Ladies Tickets

Selling 3 general admission tickets for August 4th at RBC Amphitheater.
$100 obo
I can't get the night off work anymore.

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u/TheGentleComeback — 21 days ago
▲ 1 r/PMDD

Anyone tried Myfebree daily instead of Lupron?

Found out yesterday that I could take Myfebree daily instead of taking Lupron, Progesterone, and Norlutate seperately.

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u/TheGentleComeback — 21 days ago
▲ 1 r/PMDD

I can still have kids on Lupron!

Yesterday I meet with a Physician Assistant with Trio Fertility Clinic in Toronto and found out that I can have children without coming off Lupron to get pregnant and that the use of Lupron is safe beyond 10 years as long as I have appropriate estrogen add back therapy!!
Lupron keeps my ovaries from ovulating on their own, which is why I don’t get a period. When I’m ready to have a baby, the fertility clinic doesn’t need me to stop Lupron. Instead, they’ll use fertility medications to mature my eggs while keeping my body from ovulating naturally. They’ll collect the eggs before they can be released, fertilize them in the lab, and then transfer an embryo back into my uterus at exactly the right time. Once I’m pregnant, my body naturally won’t be ovulating anymore, so I won’t need Lupron during the pregnancy.

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u/TheGentleComeback — 21 days ago

Where do you get your hair cut?

I am in my late 50's and I have medium length hair. Every salon that I go to gives me 90's short layers, no matter how much I explain and show pictures of what I want. Where are the 50 year old women in Hamilton going to get their medium to long hair cut?

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u/TheGentleComeback — 21 days ago

Woohooo! I was diagnosed yesterday

Hey!! So super exciting news! I got diagnosed with ASD Level 1 yesterday. I am a 26 year old female from Ontario, Canada. I work in health care. I like black squirrels, human behaviour, info dumping. I don't like small talk, eating with a fork, uncomfortable clothes, watching movies or TV alone.

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u/TheGentleComeback — 1 month ago
▲ 0 r/howto

How to make my bed?

I have an Ikea day bed and anytime I make the bed it looks weird because of the design on the corners and if I try to tuck in my blankets it feels like I'm gonna crush my hands.

u/TheGentleComeback — 2 months ago

What would you pay?

2014 Mazda 3 GS-Sky 2L In-Line PE
218,000km

All service records available
All weather tires
Brand new suspension
Oil undercoating annually
Oil changes every 6-8 months
No damage, no visible rust, no issues with the frame

Safetied vs not safetied. How much would you pay?

u/TheGentleComeback — 2 months ago

I can't afford a Corolla. Next best?

I can't afford a Used Corolla or Camry. What is the next best option based on reliability?
Im in canada where there is corolla with 600,000km for $6000 right now.

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u/TheGentleComeback — 2 months ago

How to handle heat when cold makes you hurt.

I have heat intolerance for many reasons and being cold makes my joints hurt very badly. How are people managing this in summer?

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u/TheGentleComeback — 2 months ago

First time travellers. Is this a good price?

Round Trip Flights

Air Canada

Toronto (YYZ) to Moncton (YQM)

Tue, Sept 8 - Mon, Sept 14

2 adults

Economy with included carry on bag. none refund.

Rental Car

Dieppe, Canada (YQM Airport)

Tue, Sept 8 - Mon, Sept 14

Passengers 4 Doors A/C

Unlimited mileage

Transmission type: Automatic

Hertz Company

TOTAL:

CA $1,348.28

Subtotal: CA $1,060.66

Taxes & fees: CA $287.62

Per traveller total: CA $674.14

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u/TheGentleComeback — 2 months ago