u/drewmullin

Need direct experiences/advice.

- Parnate 30 mg
- ~4 weeks total, 1 week at 30 mg
- Resting HR around 120
- Worse standing/walking; sometimes need to stop briefly
- BP not dangerously high

Question:
Did the tachycardia eventually go away for you on Parnate, or was it a sign it wasn’t tolerated?

Frustrating because:
- it’s helped depression more than anything in the last year w multiple med trials after quitting marplan
- but I still have significant depression/anxiety, so I don’t think I’m even at an effective dose yet

Other MAOIs:
- Marplan = not very effective overall, barely touched panic/anxiety
- Nardil = helped anxiety more but made me gain 20 lbs
- Selegiline = don’t remember much

Trying to decide:
- wait longer at 30 mg
- eventually increase
- switch to Nardil/selegiline
- or another MAOI option in the US I’m overlooking?

For those who have been on both which helped the most with extreme depression and panic disorder/ anxiety?

I've been on 30 mgs of parnate for a week now and not getting a lot back other mild tachycardia.

Also aren't I supposed to get ortho hypotension to see if I'm getting any actual effects

I'm on parnate 30 mg, only been on 30 for about 4-5 days. Some stimulation but some tiredness for sure. Seems that marplan stimulated me more? But parnate might be b more effective?

Nardil gave me weight gain so that's a no.

What about selegeline - less effective for depression and panic disorder than parnate?

Feeling stimulated helps me but can't take anything addictive- anyone got any other ideas for in combo w parnate - or maybe just higher / max dose parnate?

I know my psych talked about combining low dose of phenelzine as well, but might be more sedating? Why are maois so all over the place with effects from person to person seems wild

Thanks in advance

Hi, went from 20 to 30, was feeling a bit stimulated at 20 but now very tired. When does the stimulation part happen? Kindof need that where I am mentally. Esp when I up the medication

Also no ortho hypotension, I've had it with Nardil and marplan but not yet w parnate so I'm guessing I'm just not at high enough of a dosage bc that's apparently a sign that ur at a working dosage idk but not into the tired feeling

I know it's common esp while starting it and titrating.
I took seroquel per usual and I upped parnate today only 3rd week

For those who experience this what do yall do? It's 4:24 am nyc time and I haven't even tried to go to bed- relaxed etc but sleep- no.
I know it goes away

But what do yall do - make the best of it? Try not to think about how difficult next day no sleep and work is/ functioning

If anyone has words of wisdom would love it to hear - what to do with yourself at this hour and how not to think about how difficult tomorrow will be etc

Thanks 😊

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Who has had this and plz tell me it's just my body adjusting to it. My bph is normal - not eating any tyramine - so what's this all about and how long will it last/what helps. Can feel it physically

I have a small but decent landscaping business I run in southern Florida. We do pretty well with a chill schedule, but it's certainly not digital

I invest in real estate fix and flips in southern Florida w some success.

What else can I do to make money and live abroad - I'm at a loss but can't figure it out. Have a masters. Like South America and se Asia

Any suggestions would be great? Thx

New to this done 3 fix and flips - lost on last. Annoyed. I have not tried generating my own leads it's seems so saturated in Miami that I haven't really considered it. Have gotten on wholesalers lists etc but they all seem so overinflated w arvs etc. Tried finding partners, which has not gone well either where I have funded. Looking for advice in southern Florida I guess is what I'm trying to say

Hi new to parnate not maois- I don't have high bp or anything from food etc. First week but pretty annoying headaches- anyone have this and or remedy? Thanks

Looking for something that helps thanks

Anyone had this and what helped? Had to stop 150 cold turkey. Anyone had nightmare from this? Start other med in a week but so vivid and terrible 😣. Thanks